Gene/Proteome Database (LMPD)

LMPD ID
LMP012512
Gene ID
25440
Species
Rattus norvegicus (Rat)
Gene Name
fatty acid binding protein 6, ileal
Gene Symbol
Fabp6
Synonyms
IBABP;
Alternate Names
gastrotropin; GT; ILBP; I-15P; I-BABP; intestinal 15 kDa protein; ileal lipid-binding protein; fatty acid-binding protein 6; 14 kDa bile acid-binding protein; Fatty acid binding protein 6 (bile acid-binding protein); strain SHR/OlaIpcv fatty acid binding protein 6 (Fabp6) pseudogene;
Chromosome
10
Map Location
10q21
Summary
may mediate metabolism of steroids in steroid hormone-producing tissues [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Fabp6

Proteins

gastrotropin
Refseq ID NP_058794
Protein GI 8393346
UniProt ID P80020
mRNA ID NM_017098
Length 128
MAFTGKYEFESEKNYDEFMKRLGLPEDVIERGRNFKIITEVQQDGENFTWSQSYSGGNIMSNKFTIGKECEMQTMGGKKFKATVKMEGGKVVADFPNYHQTSEVVGDKLVEISTIGDVTYERVSKRVA

Gene Information

Entrez Gene ID
25440
Gene Name
fatty acid binding protein 6, ileal
Gene Symbol
Fabp6
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IDA:RGD C cytosol
GO:0005504 IDA:RGD F fatty acid binding
GO:0005215 IEA:InterPro F transporter activity
GO:0008202 IEP:RGD P steroid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko03320 PPAR signaling pathway
rno03320 PPAR signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR012674 Calycin
IPR011038 Calycin-like
IPR000463 Cytosolic fatty-acid binding

UniProt Annotations

Entry Information

Gene Name
fatty acid binding protein 6, ileal
Protein Entry
FABP6_RAT
UniProt ID
P80020
Species
Rat

Comments

Comment Type Description
Domain Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior
Function Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins.
Similarity Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family
Subcellular Location Cytoplasm.

Identical and Related Proteins

Unique RefSeq proteins for LMP012512 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
8393346 RefSeq NP_058794 128 gastrotropin

Identical Sequences to LMP012512 proteins

Reference Database Accession Length Protein Name
GI:8393346 GenBank AAB24948.1 128 intestinal 15 kda protein [Rattus sp.]
GI:8393346 GenBank AAA57155.1 128 bile acid-binding protein [Rattus norvegicus]

Related Sequences to LMP012512 proteins

Reference Database Accession Length Protein Name
GI:8393346 GenBank AAB24948.1 128 intestinal 15 kda protein [Rattus sp.]
GI:8393346 GenBank AAA57155.1 128 bile acid-binding protein [Rattus norvegicus]
GI:8393346 SwissProt P80020.3 128 RecName: Full=Gastrotropin; Short=GT; AltName: Full=14 kDa bile acid-binding protein; AltName: Full=Fatty acid-binding protein 6; AltName: Full=I-BABP; AltName: Full=Ileal lipid-binding protein; Short=ILBP; AltName: Full=Intestinal 15 kDa protein; Short=I-15P [Rattus norvegicus]