Gene/Proteome Database (LMPD)

LMPD ID
LMP012012
Gene ID
555443
Species
Danio rerio (Zebrafish)
Gene Name
phospholipase C, delta 1a
Gene Symbol
plcd1a
Synonyms
zgc:165641
Chromosome
24

Proteins

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Refseq ID NP_001103170
Protein GI 157841242
UniProt ID A7MD68
mRNA ID NM_001109700
Length 775
RefSeq Status PROVISIONAL
MSCPFKPLKRTKSEEFIYQEKSKNVSKENGKRIGLDEDPDLQFLLRGGDLIKVKSNSWKKTRFLKLNEDCKTIYQSSSKAFKRESSFELAEIDSVRLGRQSEGLQKYTYSSIENRCFSIIFKGRRENLDLIASSDDEANCWVNSLEKVINRLHKLNRQQNSEHWIYECMRKADKNADNKMSLKELKHFLRQINIEVNDSYAETLFRKCDTSNSGTLEGSEIKLFYNLLTQRDEIDVIYDKYATSNGQMSRNDLLNFIQLEQREPVSLGYAEELIKKYEVDETAKQDKHMSKDGFLMYLNQEGTLLNPAHIDVYQDMQQPLNHYFISSSHNTYLMEDQLKGPSSTEAYIKALMKSCRCVELDIWDGANGEPVIYYGHTLTSKVPFKDVIKAIKDYAFKASPYPVILSLENHCSLEQQKIVAMHLTTILGSALLTQPLGQKMPTTFPGPEDLKGRFLIKGKRLNKLDAAFNNNTAEDVESVSEEDEAADLKEGEPTHKDSKKSKKIKLAKELSDLVVYCKSVHFTSFEQSRKKQAFYEMASFKEGKAMNLAEQSANAFIRHNIDKLSRIYPAGSRTDSSNYNPVPLWNAGCQIVALNFLTPCKEMDLNQARFLPNGKSGYILKPEFLRDPASQFDPINLRKGPWLQKKVLHIMVISAQQLPKINKNKEKSIVDPHVRVEIYGVPQDNASKQTHHIDNNGFNPMWNTNFQFTVNVPELALVRFVVEDYDAASKNDLIGLYTIPLTSMQNGYRHMPLLTKRGIIIPSAGLFVHVMLLDA

Gene Information

Entrez Gene ID
555443
Gene Name
phospholipase C, delta 1a
Gene Symbol
plcd1a
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR028391 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, delta 1a
Protein Entry
A7MD68_DANRE
UniProt ID
A7MD68
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 3 EF-hand domains.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP012012 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157841242 RefSeq NP_001103170 775 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

Identical Sequences to LMP012012 proteins

Reference Database Accession Length Protein Name
GI:157841242 GenBank AAI52503.1 775 Plcd1a protein [Danio rerio]

Related Sequences to LMP012012 proteins

Reference Database Accession Length Protein Name
GI:157841242 RefSeq XP_003968055.1 774 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like [Takifugu rubripes]
GI:157841242 RefSeq XP_004081132.1 771 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform 2 [Oryzias latipes]
GI:157841242 RefSeq XP_005162758.1 752 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [Danio rerio]
GI:157841242 RefSeq XP_005448920.1 775 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform X2 [Oreochromis niloticus]
GI:157841242 RefSeq XP_008295953.1 774 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [Stegastes partitus]
GI:157841242 RefSeq XP_008306153.1 774 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [Cynoglossus semilaevis]