Gene/Proteome Database (LMPD)

LMPD ID
LMP011897
Gene ID
492502
Species
Danio rerio (Zebrafish)
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Gene Symbol
plekha8
Synonyms
wu:fc68b04; zgc:101886
Alternate Names
pleckstrin homology domain-containing family A member 8; fc68b04; PH domain-containing family A member 8
Chromosome
16

Proteins

pleckstrin homology domain-containing family A member 8
Refseq ID NP_001007375
Protein GI 55925185
UniProt ID Q5U3N0
mRNA ID NM_001007374
Length 549
RefSeq Status PROVISIONAL
MEGVLYKWTNYISGWQPRWFVLEGGTLSYYDSQEDAWKGCKGSIKISVCEIQVHPSDFTRVDLIIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNRTKREKELQENSEALKTKMSELRLYCDLLLQQVNKIQESPLAETSAGSGEGGDETGNLVKSTCTTFLKTLEECMHIASRTFNPDLLSRTPPGSPSVATIKPQKIKSNDPKNLHPGETRKDLINTSGTSAHESGPDNEPPPSPQENISTAHTESGLMEDQNDLIEPNNGSSSSTQDHEEPVEEQQTDGSTEDADHSQEEQQEVSMSPTQNKQEVQEDIQTDLELNETQSENKQEEEDEDKVDTFFSTMSHRFSDIILEEDSGIPTQAFLDSCYAIVPVLDKLGPTVFAPVKIDFVGNIKKIQQKVVSDPESFPTLQSIVLHEVKTEVAQVRNSATEALLWLKRGLKFLKEFLSEINTGVKDVQGALYNAYGKTLRQYHGWVVRGVFALALRAAPSYEGFMAALVSYEGDELKEGFRTGMHRDLDIYLPAMENQLSILDTLYEEYGLESDEIV

Gene Information

Entrez Gene ID
492502
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Gene Symbol
plekha8
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0051861 IEA:InterPro F glycolipid binding
GO:0017089 IEA:InterPro F glycolipid transporter activity
GO:0015031 IEA:UniProtKB-KW P protein transport

Domain Information

InterPro Annotations

Accession Description
IPR014830 Glycolipid transfer protein domain
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Protein Entry
PKHA8_DANRE
UniProt ID
Q5U3N0
Species
Zebrafish

Comments

Comment Type Description
Function Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN) to the plasma membrane. {ECO:0000250}.
Similarity Contains 1 PH domain. {ECO:0000255|PROSITE- ProRule:PRU00145}.
Subcellular Location Cytoplasm {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Mainly localized to the trans-Golgi network (TGN) but also found at the rims of Golgi cisternae. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011897 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
55925185 RefSeq NP_001007375 549 pleckstrin homology domain-containing family A member 8

Identical Sequences to LMP011897 proteins

Reference Database Accession Length Protein Name
GI:55925185 GenBank AAH85465.1 549 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 [Danio rerio]
GI:55925185 SwissProt Q5U3N0.1 549 RecName: Full=Pleckstrin homology domain-containing family A member 8; Short=PH domain-containing family A member 8 [Danio rerio]

Related Sequences to LMP011897 proteins

Reference Database Accession Length Protein Name
GI:55925185 GenBank AHH40570.1 568 Pleckstrin homology domain-containing family A member 8 [Ictalurus punctatus]
GI:55925185 RefSeq XP_003454483.1 562 PREDICTED: pleckstrin homology domain-containing family A member 8-like [Oreochromis niloticus]
GI:55925185 RefSeq XP_005738515.1 562 PREDICTED: pleckstrin homology domain-containing family A member 8-like [Pundamilia nyererei]
GI:55925185 RefSeq XP_005934808.1 562 PREDICTED: pleckstrin homology domain-containing family A member 8-like [Haplochromis burtoni]
GI:55925185 RefSeq XP_007233447.1 554 PREDICTED: pleckstrin homology domain-containing family A member 8 [Astyanax mexicanus]
GI:55925185 RefSeq XP_008289282.1 563 PREDICTED: pleckstrin homology domain-containing family A member 8 [Stegastes partitus]