LIPID MAPS

LMPD ID

LMP011754

Gene ID

406408

Species

Danio rerio (Zebrafish)

Gene Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)

Gene Symbol

ddost

Synonyms

zgc:66068; zgc:77478; wu:fa11d01

Alternate Names

dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; DDOST 48 kDa subunit; oligosaccharyl transferase 48 kDa subunit; dolichyl-diphosphooligosaccharide-protein glycosyltransferase

Chromosome

23

EC Number

2.4.99.18

dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor
Refseq ID	NP_998258
Protein GI	47085831
UniProt ID	Q6NYS8
mRNA ID	NM_213093
Length	441
RefSeq Status	PROVISIONAL
MATALSGGFSKNALFILSAALMLQAVLGDGKTLVLLDNPNIRDTHSIFFRSLADRGFDLTFKTADDPGLSLLKYGQFLYDHLILFSPSVEDFGGNINVETITAFIDGGGNVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDPGEHTLIVADPENLLKAPTIVGKPTDKPVLFKGVGMVADPDNPLVLDILTGSSTSYSYFPDRPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLHFFSDAFFNSAVQKAATGSKRYEQTGNQDLAEALSRWVFKEAGVLRVGDVTHHPVGESTPPAAYTVTDLVEYGIVIEMLSGGKWVPFDGDDIQLEFVRIDPFVRTYLKKNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAFPYYASAFSMMAGLFVFSVVFLHMREKEKSD

Entrez Gene ID

406408

Gene Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)

Gene Symbol

ddost

Species

Danio rerio

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005789	IEA:InterPro	C	endoplasmic reticulum membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0004579	IEA:InterPro	F	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0018279	IEA:InterPro	P	protein N-linked glycosylation via asparagine

KEGG Pathway Links

KEGG Pathway ID	Description
dre00510	N-Glycan biosynthesis
dre_M00072	N-glycosylation by oligosaccharyltransferase
dre04141	Protein processing in endoplasmic reticulum

REACTOME Pathway Links

REACTOME Pathway ID	Description
6176685	Advanced glycosylation endproduct receptor signaling

InterPro Annotations

Accession	Description
IPR005013	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

Entry Information

Gene Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)

Protein Entry

OST48_DANRE

UniProt ID

Q6NYS8

Species

Zebrafish

Comments

Comment Type	Description
Catalytic Activity	Dolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Function	Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. {ECO:0000250}.
Pathway	Protein modification; protein glycosylation.
Similarity	Belongs to the DDOST 48 kDa subunit family. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Subunit	Component of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.

Unique RefSeq proteins for LMP011754 (as displayed in Record Overview)

Protein GI	Database	Accession	Length	Protein Name
47085831	RefSeq	NP_998258	441	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor

Identical Sequences to LMP011754 proteins

Reference	Database	Accession	Length	Protein Name
GI:47085831	GenBank	AAH66475.1	441	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase [Danio rerio]

Related Sequences to LMP011754 proteins

Reference	Database	Accession	Length	Protein Name
GI:47085831	GenBank	AAH56559.1	441	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase [Danio rerio]
GI:47085831	GenBank	AHH42660.1	466	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [Ictalurus punctatus]
GI:47085831	RefSeq	XP_007246315.1	458	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [Astyanax mexicanus]
GI:47085831	RefSeq	XP_008293491.1	466	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [Stegastes partitus]
GI:47085831	RefSeq	XP_008316674.1	466	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [Cynoglossus semilaevis]
GI:47085831	SwissProt	Q6NYS8.2	441	RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Short=DDOST 48 kDa subunit; Short=Oligosaccharyl transferase 48 kDa subunit; Flags: Precursor [Danio rerio]