Gene/Proteome Database (LMPD)

LMPD ID
LMP011628
Gene ID
373124
Species
Danio rerio (Zebrafish)
Gene Name
phosphatidylinositol-4-phosphate 5-kinase, type II
Gene Symbol
pip5k2
Synonyms
cb770; Pip5k2c; pip4k2c; zgc:56046
Alternate Names
phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; PIP4KII-gamma; PI(5)P 4-kinase type II gamma; 1-phosphatidylinositol-5-phosphate 4-kinase C; phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; phosphatidylinositol 5-phosphate 4-kinase type II gamma; phosphatidylinositol-5-phosphate 4-kinase type II gamma; phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
Chromosome
23
EC Number
2.7.1.149

Proteins

phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Refseq ID NP_956395
Protein GI 48976047
UniProt ID Q6IQE1
mRNA ID NM_200101
Length 416
RefSeq Status PROVISIONAL
MASLGNSGSASSPMVMLAPKTKTKKRHFMQQKVKVFRASDPMLSVFMWGVNHSINDLNQVPVPVMLLPDDFKANTKIKVNNHLFNKENLPSHFEFKEYCPQVFRNLRERFGIEDLDYQASLARSAPMKGDGQGEGLLFTSYDRTLIVKQISSEEVADMHNILSEYHQHIVKCHGSTLLPQFLGMYRITVESEDTYLIVMRNMFSHRLLVHRKYDLKGSLVDREASDKEKVKELPTFKDMDFRNNMQKVYVTEEQKEKMMEKLNRDVEFLVKLKIMDYSLLLGIHDVARGEREEEEAEEPCYEDDADPENGLAPALQVGSYGTSPEGIAGYMNSIKPLGPGEFDPYIDVYAVKSAPGAPQREVYFMGLIDVLTQYDTKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFREFISNIFA

Gene Information

Entrez Gene ID
373124
Gene Name
phosphatidylinositol-4-phosphate 5-kinase, type II
Gene Symbol
pip5k2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0016309 IEA:UniProtKB-EC F 1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding

KEGG Pathway Links

KEGG Pathway ID Description
dre00562 Inositol phosphate metabolism
dre04070 Phosphatidylinositol signaling system
dre04810 Regulation of actin cytoskeleton
ko04810 Regulation of actin cytoskeleton

Domain Information

InterPro Annotations

Accession Description
IPR023610 Phosphatidylinositol-4-phosphate 5-kinase
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol-4-phosphate 5-kinase, type II
Protein Entry
PI42C_DANRE
UniProt ID
Q6IQE1
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity ATP + 1-phosphatidyl-1D-myo-inositol 5- phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
Function May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2).
Similarity Contains 1 PIPK domain. {ECO:0000255|PROSITE- ProRule:PRU00781}.
Subcellular Location Cytoplasm. Membrane {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011628 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
48976047 RefSeq NP_956395 416 phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

Identical Sequences to LMP011628 proteins

Reference Database Accession Length Protein Name
GI:48976047 GenBank AAH71466.1 416 Phosphatidylinositol-4-phosphate 5-kinase, type II [Danio rerio]
GI:48976047 SwissProt Q6IQE1.1 416 RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II gamma; Short=PI(5)P 4-kinase type II gamma; Short=PIP4KII-gamma [Danio rerio]

Related Sequences to LMP011628 proteins

Reference Database Accession Length Protein Name
GI:48976047 GenBank AAH45883.1 416 Phosphatidylinositol-4-phosphate 5-kinase, type II [Danio rerio]
GI:48976047 GenBank AHH39095.1 416 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [Ictalurus punctatus]
GI:48976047 RefSeq XP_003457105.1 416 PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform X1 [Oreochromis niloticus]
GI:48976047 RefSeq XP_004560306.1 416 PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like [Maylandia zebra]
GI:48976047 RefSeq XP_005918800.1 416 PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform X1 [Haplochromis burtoni]
GI:48976047 RefSeq XP_008317228.1 417 PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [Cynoglossus semilaevis]