Gene/Proteome Database (LMPD)

LMPD ID
LMP011229
Gene ID
835157
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
pyruvate dehydrogenase E1 beta
Gene Symbol
MAB1
Synonyms
K16E14.6; MAB1; MACCI-BOU
Alternate Names
pyruvate dehydrogenase E1 beta
Chromosome
5
EC Number
1.2.4.1

Proteins

pyruvate dehydrogenase E1 beta
Refseq ID NP_199898
Protein GI 15241286
UniProt ID Q38799
mRNA ID NM_124463
Length 363
RefSeq Status REVIEWED
MLGILRQRAIDGASTLRRTRFALVSARSYAAGAKEMTVRDALNSAIDEEMSADPKVFVMGEEVGQYQGAYKITKGLLEKYGPERVYDTPITEAGFTGIGVGAAYAGLKPVVEFMTFNFSMQAIDHIINSAAKSNYMSAGQINVPIVFRGPNGAAAGVGAQHSQCYAAWYASVPGLKVLAPYSAEDARGLLKAAIRDPDPVVFLENELLYGESFPISEEALDSSFCLPIGKAKIEREGKDVTIVTFSKMVGFALKAAEKLAEEGISAEVINLRSIRPLDRATINASVRKTSRLVTVEEGFPQHGVCAEICASVVEESFSYLDAPVERIAGADVPMPYAANLERLALPQIEDIVRASKRACYRSK

Gene Information

Entrez Gene ID
835157
Gene Name
pyruvate dehydrogenase E1 beta
Gene Symbol
MAB1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0048046 IDA:TAIR C apoplast
GO:0005739 IDA:TAIR C mitochondrion
GO:0005730 IDA:TAIR C nucleolus
GO:0005774 IDA:TAIR C vacuolar membrane
GO:0004739 IEA:UniProtKB-EC F pyruvate dehydrogenase (acetyl-transferring) activity
GO:0006086 IEA:InterPro P acetyl-CoA biosynthetic process from pyruvate
GO:0042742 IEP:TAIR P defense response to bacterium
GO:0006096 IEA:UniProtKB-KW P glycolytic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01200 Carbon metabolism
ath00020 Citrate cycle (TCA cycle)
ath00010 Glycolysis / Gluconeogenesis
ath_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA

Domain Information

InterPro Annotations

Accession Description
IPR027110 Pyruvate dehydrogenase E1 component subunit beta
IPR029061 Thiamin diphosphate-binding fold
IPR005476 Transketolase, C-terminal
IPR009014 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR005475 Transketolase-like, pyrimidine-binding domain

UniProt Annotations

Entry Information

Gene Name
pyruvate dehydrogenase E1 beta
Protein Entry
ODPB1_ARATH
UniProt ID
Q38799
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2).
Cofactor Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:14671022}.
Subunit Tetramer of 2 alpha and 2 beta subunits. {ECO:0000250}.
Tissue Specificity Expressed in roots, immature rosettes, and mature rosettes. {ECO:0000269|PubMed:8061040}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011229 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15241286 RefSeq NP_199898 363 pyruvate dehydrogenase E1 beta

Identical Sequences to LMP011229 proteins

Reference Database Accession Length Protein Name
GI:15241286 DBBJ BAA98121.1 363 pyruvate dehydrogenase E1 component beta subunit, mitochondrial precursor (PDHE1-B) [Arabidopsis thaliana]
GI:15241286 GenBank AAL50070.1 363 AT5g50850/K16E14_1 [Arabidopsis thaliana]
GI:15241286 GenBank AAN38676.1 363 At5g50850/K16E14_1 [Arabidopsis thaliana]
GI:15241286 gnl TAIR 363 pyruvate dehydrogenase E1 beta [Arabidopsis thaliana]
GI:15241286 SwissProt Q38799.2 363 RecName: Full=Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial; Short=PDHE1-B; AltName: Full=Protein MACCI-BOU; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP011229 proteins

Reference Database Accession Length Protein Name
GI:15241286 GenBank AAA52225.1 363 pyruvate dehydrogenase E1 beta subunit [Arabidopsis thaliana]
GI:15241286 GenBank AAW00663.1 363 Sequence 44 from patent US 6773917
GI:15241286 GenBank ACX06013.1 363 Sequence 29406 from patent US 7569389
GI:15241286 GenBank EFH40339.1 366 pyruvate dehydrogenase E1 component beta subunit, mitochondrial [Arabidopsis lyrata subsp. lyrata]
GI:15241286 GenBank AFL41904.1 363 Sequence 2812 from patent US 8183436
GI:15241286 PRF - 363 pyruvate dehydrogenase [Arabidopsis thaliana]