Gene/Proteome Database (LMPD)

LMPD ID
LMP011130
Gene ID
837255
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
protein phosphatase 2C 3
Gene Symbol
HAI2
Synonyms
F22G5.22; F22G5_22; HAI2; highly ABA-induced PP2C gene 2
Alternate Names
protein phosphatase 2C 3
Chromosome
1
EC Number
3.1.3.16

Proteins

protein phosphatase 2C 3
Refseq ID NP_172223
Protein GI 15222398
UniProt ID Q9LNW3
mRNA ID NM_100617
Length 442
RefSeq Status REVIEWED
MADICYEDETSACESRPLWSSRKWRIGVQRFRMSPSEMNPTASTTEEEDKSEGIYNKRNKQEEYDFMNCASSSPSQSSPEEESVSLEDSDVSISDGNSSVNDVAVIPSKKTVKETDLRPRYGVASVCGRRRDMEDAVALHPSFVRKQTEFSRTRWHYFGVYDGHGCSHVAARCKERLHELVQEEALSDKKEEWKKMMERSFTRMDKEVVRWGETVMSANCRCELQTPDCDAVGSTAVVSVITPEKIIVANCGDSRAVLCRNGKAVPLSTDHKPDRPDELDRIQEAGGRVIYWDGARVLGVLAMSRAIGDNYLKPYVTSEPEVTVTDRTEEDEFLILATDGLWDVVTNEAACTMVRMCLNRKSGRGRRRGETQTPGRRSEEEGKEEEEKVVGSRKNGKRGEITDKACTEASVLLTKLALAKHSSDNVSVVVIDLRRRRKRHVA

Gene Information

Entrez Gene ID
837255
Gene Name
protein phosphatase 2C 3
Gene Symbol
HAI2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0005267 IEA:UniProtKB-KW F potassium channel activity
GO:0004722 IEA:InterPro F protein serine/threonine phosphatase activity
GO:0009788 IMP:TAIR P negative regulation of abscisic acid-activated signaling pathway
GO:1902039 IMP:TAIR P negative regulation of seed dormancy process
GO:0009939 IMP:TAIR P positive regulation of gibberellic acid mediated signaling pathway
GO:0010030 IMP:TAIR P positive regulation of seed germination
GO:0006470 IEA:InterPro P protein dephosphorylation
GO:0048838 IMP:TAIR P release of seed from dormancy

KEGG Pathway Links

KEGG Pathway ID Description
ath04075 Plant hormone signal transduction
ko04075 Plant hormone signal transduction

Domain Information

InterPro Annotations

Accession Description
IPR015655 Protein phosphatase 2C
IPR001932 Protein phosphatase 2C (PP2C)-like domain
IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site

UniProt Annotations

Entry Information

Gene Name
protein phosphatase 2C 3
Protein Entry
P2C03_ARATH
UniProt ID
Q9LNW3
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 magnesium or manganese ions per subunit. {ECO:0000250};
Function Involved in the negative regulation of the K(+) potassium channel AKT1 by its dephosphorylation, antagonistically to CIPK proteins (e.g. CIPK23). {ECO:0000269|PubMed:17898163}.
Similarity Belongs to the PP2C family. {ECO:0000305}.
Similarity Contains 1 PP2C-like domain. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000305}. Note=Probably associated to the plasma membrane when interacting with AKT1 and CIPK23.
Subunit Part of a K(+)-channel calcium-sensing kinase/phosphatase complex composed by a calcium sensor CBL (CBL1, CBL2, CBL3 or CBL9), a kinase CIPK (CIPK6, CIPK16 or CIPK23), a phosphatase PP2C (AIP1) and a K(+)-channel (AKT1). Interacts with AKT1 and CIPK23. {ECO:0000269|PubMed:17898163}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011130 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15222398 RefSeq NP_172223 442 protein phosphatase 2C 3

Identical Sequences to LMP011130 proteins

Reference Database Accession Length Protein Name
GI:15222398 EMBL CAW50645.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CAW53893.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CBC26392.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CBC19861.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 GenBank AEE28124.1 442 protein phosphatase 2C 3 [Arabidopsis thaliana]
GI:15222398 SwissProt Q9LNW3.1 442 RecName: Full=Protein phosphatase 2C 3; Short=AtPP2C03; AltName: Full=Protein AKT1-INTERACTING 1; AltName: Full=Protein phosphatase 2C AIP1; Short=PP2C AIP1 [Arabidopsis thaliana]

Related Sequences to LMP011130 proteins

Reference Database Accession Length Protein Name
GI:15222398 EMBL CAW50752.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CAW54000.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CBC26604.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 EMBL CBC20084.1 442 unnamed protein product [Arabidopsis thaliana]
GI:15222398 GenBank AAM61361.1 442 protein phosphatase 2C, putative [Arabidopsis thaliana]
GI:15222398 RefSeq XP_003414638.1 751 PREDICTED: protein phosphatase 1E [Loxodonta africana]