Gene/Proteome Database (LMPD)
LMPD ID
LMP011099
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
protein FLOWERING LOCUS T
Gene Symbol
Synonyms
F5I14.3; F5I14_3; FLOWERING LOCUS T; FT
Alternate Names
protein FLOWERING LOCUS T
Chromosome
1
Summary
FT, together with LFY, promotes flowering and is antagonistic with its homologous gene, TERMINAL FLOWER1 (TFL1). FT is expressed in leaves and is induced by long day treatment. Either the FT mRNA or protein is translocated to the shoot apex where it induces its own expression. Recent data suggests that FT protein acts as a long-range signal. FT is a target of CO and acts upstream of SOC1.
Orthologs
Proteins
| protein FLOWERING LOCUS T | |
|---|---|
| Refseq ID | NP_176726 |
| Protein GI | 15218709 |
| UniProt ID | Q9SXZ2 |
| mRNA ID | NM_105222 |
| Length | 175 |
| RefSeq Status | REVIEWED |
| MSINIRDPLIVSRVVGDVLDPFNRSITLKVTYGQREVTNGLDLRPSQVQNKPRVEIGGEDLRNFYTLVMVDPDVPSPSNPHLREYLHWLVTDIPATTGTTFGNEIVCYENPSPTAGIHRVVFILFRQLGRQTVYAPGWRQNFNTREFAEIYNLGLPVAAVFYNCQRESGCGGRRL | |
Gene Information
Entrez Gene ID
Gene Name
protein FLOWERING LOCUS T
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005737 | IDA:TAIR | C | cytoplasm |
| GO:0005634 | IDA:TAIR | C | nucleus |
| GO:0008429 | ISS:TAIR | F | phosphatidylethanolamine binding |
| GO:0030154 | IEA:UniProtKB-KW | P | cell differentiation |
| GO:0009908 | IEA:UniProtKB-KW | P | flower development |
| GO:0048573 | IEP:TAIR | P | photoperiodism, flowering |
| GO:0009911 | IMP:TAIR | P | positive regulation of flower development |
| GO:0009909 | IGI:TAIR | P | regulation of flower development |
| GO:0010119 | IMP:TAIR | P | regulation of stomatal movement |
KEGG Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=2; Name=Long; IsoId=Q9SXZ2-1; Sequence=Displayed; Name=Short; IsoId=Q9SXZ2-2; Sequence=VSP_004543, VSP_004544; |
| Developmental Stage | Expression gradually increases with time under both long-day (LD) and short-day (SD) photoperiods. Under LD conditions, expression is first detected on day 4 and plateaued around day 6, preceeding floral commitment around days 9 and 10. |
| Function | Probable component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. May play a role in both the autonomous and the long- day flowering pathways. {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:16099980, ECO:0000269|PubMed:16155177}. |
| Induction | By light. Expression is delayed and reduced under SD conditions. Repressed by FLC. Up-Regulated by VOZ1 and/or VOZ2. {ECO:0000269|PubMed:16099980, ECO:0000269|PubMed:22904146}. |
| Interaction | Q84JK2:FD; NbExp=4; IntAct=EBI-636490, EBI-636507; Q9FVI6:HDG6; NbExp=2; IntAct=EBI-636490, EBI-1393271; |
| Miscellaneous | Mutagenesis of Tyr-85 to His converts the activator of flowering "FLOWERING LOCUS T" into a "TERMINAL FLOWER 1"-like repressor of flowering. |
| Similarity | Belongs to the phosphatidylethanolamine-binding protein family. {ECO:0000305}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16099979}. Nucleus {ECO:0000269|PubMed:16099979}. |
| Subunit | Interacts with FD/BZIP14. {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:16099980}. |
| Tissue Specificity | Mostly localized in leaves vasculature. Transcripts can move in the phloem from leaves to shoot apex at a velocity between 1.2 and 3.5 mm/h. {ECO:0000269|PubMed:15618421, ECO:0000269|PubMed:16099949}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP011099 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15218709 | RefSeq | NP_176726 | 175 | protein FLOWERING LOCUS T |
Identical Sequences to LMP011099 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15218709 | GenBank | ADA52843.1 | 175 | Sequence 3 from patent US 7626082 |
| GI:15218709 | GenBank | ADM07019.1 | 175 | Sequence 61 from patent US 7732668 |
| GI:15218709 | GenBank | ADS20520.1 | 175 | Sequence 14 from patent US 7767884 |
| GI:15218709 | GenBank | AEE34381.1 | 175 | protein FLOWERING LOCUS T [Arabidopsis thaliana] |
| GI:15218709 | GenBank | AFX49889.1 | 175 | Sequence 51722 from patent US 8299318 |
| GI:15218709 | GenBank | AGD03320.1 | 175 | Sequence 776 from patent US 8343764 |
Related Sequences to LMP011099 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15218709 | GenBank | ABI00126.1 | 173 | Sequence 513 from patent US 7071380 |
| GI:15218709 | GenBank | ABI00127.1 | 174 | Sequence 514 from patent US 7071380 |
| GI:15218709 | GenBank | ABI00154.1 | 174 | Sequence 541 from patent US 7071380 |
| GI:15218709 | GenBank | AFX28440.1 | 297 | Sequence 9500 from patent US 8299318 |
| GI:15218709 | GenBank | AFX49923.1 | 297 | Sequence 51756 from patent US 8299318 |
| GI:15218709 | GenBank | AGF13969.1 | 297 | Sequence 13388 from patent US 8362325 |