Gene/Proteome Database (LMPD)

LMPD ID
LMP010976
Gene ID
829556
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
probable E3 ubiquitin ligase SUD1
Gene Symbol
AT4G34100
Synonyms
F28A23.140; F28A23_140
Alternate Names
probable E3 ubiquitin ligase SUD1
Chromosome
4
EC Number
6.3.2.-

Proteins

probable E3 ubiquitin ligase SUD1
Refseq ID NP_195136
Protein GI 145352486
UniProt ID F4JKK0
mRNA ID NM_119571
Length 1108
RefSeq Status REVIEWED
MEISPADSLSISGAAASEVVSEPSVSSSSSSSSPNQASPNPFSNMDPAVSTATGSRYVDDDEDEEDVCRICRNPGDADNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKHPFSFSPVYADNAPSRLPFQEFVVGIAMKACHVLQFFLRLSFVLSVWLLTIPFITFWIWRLAFVRTFGEAQRLFLSHISTTVILTDCLHGFLLSASIVFIFLGATSLRDYFRHLRELGGQEERDDDVDRNGARAARRPAGQANRNLAGEGNGEDAGDQGAAVGQIARRNPENVLARLDIQAARLEAQVEQMFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNMIFLGVVIFVPFTLGRIILYHVSWLFAAARGPAVAASLHLTDTGLSLENITLKSALTAVSNLTSEGQGNGLLGQLTEMMKVNGSELNGANNTLSVATDLLKGSTVGASKLSDITTLAVGYMFIVFLVFLYLGIIALIRYAKGEPLTVGRFYGIASIVEAVPSLLRQFLAAMRHLMTMIKVAFLLVIELGVFPLMCGWWLDVCTVRMFGKTMSHRVQFLSISPLASSLVHWVVGIMYMLQISIFVSLLRGVLRPGVLYFLRDPADPNYNPFRDLIDDPVHKHARRVLLSVAVYGSLIVMLVFLPVKLAIRMAPSIFPLDISVSDPFTEIPADMLLFQICIPFIIEHFRLRTTIKSLLRCWFTGVGWALGLTDFLLPRPEDNIGQDNGNGEPGRQNRAQVLQVGGPDRAMAALPVADDPNRSRLRAGNVNTGEEYEDDDEQSDSDRYNFVVRIILLLLVAWVTLLLFNSALIVVPVSLGRALFSAIPILPITHGIKCNDLYAFVIGTYAFWTTISGARYAIEHVKSKRTSVLLNQIWKWCGIVFKSSVLLAIWVFIIPVLIGLLFELLVIVPMRVPVDESPVFLLYQDWALGLIFLKIWTRLVMLDHMLPIVDDSWRAKFERVREDGFSRLQGLWVLREIVFPIVMKLLTALCVPYVLARGVFPMLGYPLVVNSAVYRFAWIGCLSVSLFCFCAKRCHVWFRNLHNSIRDDRYLIGRRLHNFGEAALANQNQNQSSEDAGDGVLIGREGDVDNGLRLRRAIQQEA
probable E3 ubiquitin ligase SUD1
Refseq ID NP_001119113
Protein GI 186516113
UniProt ID F4JKK0
mRNA ID NM_001125641
Length 1107
RefSeq Status REVIEWED
MEISPADSLSISGAAASEVVSEPSVSSSSSSSSPNQASPNPFSNMDPAVSTATGSRYVDDDEDEEDVCRICRNPGDADNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKHPFSFSPVYADNAPSRLPFQEFVVGIAMKACHVLQFFLRLSFVLSVWLLTIPFITFWIWRLAFVRTFGEAQRLFLSHISTTVILTDCLHGFLLSASIVFIFLGATSLRDYFRHLRELGGQEERDDDVDRNGARAARRPAGQANRNLAGEGNGEDAGDQGAAVGQIARRNPENVLARLDIQAARLEAQVEQMFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNMIFLGVVIFVPFTLGRIILYHVSWLFAAARGPAVAASLHLTDTGLSLENITLKSALTAVSNLTSEGQGNGLLGQLTEMMKVNGSELNGANNTLSVATDLLKGSTVGASKLSDITTLAVGYMFIVFLVFLYLGIIALIRYAKGEPLTVGRFYGIASIVEAVPSLLRQFLAAMRHLMTMIKVAFLLVIELGVFPLMCGWWLDVCTVRMFGKTMSHRVQFLSISPLASSLVHWVVGIMYMLQISIFVSLLRGVLRPGVLYFLRDPADPNYNPFRDLIDDPVHKHARRVLLSVAVYGSLIVMLVFLPVKLAIRMAPSIFPLDISVSDPFTEIPADMLLFQICIPFIIEHFRLRTTIKSLLRCWFTGVGWALGLTDFLLPRPEDNIGQDNGNGEPGRQNRAQVLQVGGPDRAMAALPVADDPNRSRLRAGNVNTGEEYEDDDEQSDSEYNFVVRIILLLLVAWVTLLLFNSALIVVPVSLGRALFSAIPILPITHGIKCNDLYAFVIGTYAFWTTISGARYAIEHVKSKRTSVLLNQIWKWCGIVFKSSVLLAIWVFIIPVLIGLLFELLVIVPMRVPVDESPVFLLYQDWALGLIFLKIWTRLVMLDHMLPIVDDSWRAKFERVREDGFSRLQGLWVLREIVFPIVMKLLTALCVPYVLARGVFPMLGYPLVVNSAVYRFAWIGCLSVSLFCFCAKRCHVWFRNLHNSIRDDRYLIGRRLHNFGEAALANQNQNQSSEDAGDGVLIGREGDVDNGLRLRRAIQQEA

Gene Information

Entrez Gene ID
829556
Gene Name
probable E3 ubiquitin ligase SUD1
Gene Symbol
AT4G34100
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016874 IEA:UniProtKB-KW F ligase activity
GO:0004842 TAS:TAIR F ubiquitin-protein transferase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0010143 IMP:TAIR P cutin biosynthetic process
GO:0008299 IMP:TAIR P isoprenoid biosynthetic process
GO:1900490 IMP:TAIR P positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0009414 IGI:TAIR P response to water deprivation
GO:0010345 IMP:TAIR P suberin biosynthetic process
GO:0010025 IMP:TAIR P wax biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath04141 Protein processing in endoplasmic reticulum
ko04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR011016 Zinc finger, RING-CH-type
IPR013083 Zinc finger, RING/FYVE/PHD-type

UniProt Annotations

Entry Information

Gene Name
probable E3 ubiquitin ligase SUD1
Protein Entry
SUD1_ARATH
UniProt ID
F4JKK0
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=F4JKK0-1; Sequence=Displayed; Name=2; IsoId=F4JKK0-2; Sequence=VSP_046615; Note=Derived from EST data.;
Developmental Stage Constitutively expressed throughout development. {ECO:0000269|PubMed:22635115}.
Disruption Phenotype Semiglossy stem. Elevated drought tolerance and reduced transpiration rate. Elevated amounts of 18-carbon- length cutin monomers and shift in the cuticular wax profile toward the very-long-chain free fatty acids tetracosanoic acid (C24) and hexacosanoic acid (C26). {ECO:0000269|PubMed:22635115}.
Domain The RING-CH-type zinc finger domain is required for E3 ligase activity. {ECO:0000255|PROSITE-ProRule:PRU00623}.
Function Probable E3 ubiquitin ligase acting as a positive post- transcriptional regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. Might be involved in the quality control that degrades misfolded proteins (By similarity). {ECO:0000250}.
Pathway Protein modification; protein ubiquitination.
Sequence Caution Sequence=CAA17562.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB80127.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Contains 1 RING-CH-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00623}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in cotyledons, leaves, roots, stems, inflorescences and siliques. Expression higher at the top than at the base of the stem. {ECO:0000269|PubMed:22635115}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010976 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
145352486 RefSeq NP_195136 1108 probable E3 ubiquitin ligase SUD1
186516113 RefSeq NP_001119113 1107 probable E3 ubiquitin ligase SUD1

Identical Sequences to LMP010976 proteins

Reference Database Accession Length Protein Name
GI:145352486 GenBank AEE86323.1 1108 cuticular wax biosynthesis protein [Arabidopsis thaliana]
GI:186516113 GenBank AEE86324.1 1107 cuticular wax biosynthesis protein [Arabidopsis thaliana]
GI:145352486 SwissProt F4JKK0.1 1108 RecName: Full=Probable E3 ubiquitin ligase SUD1; AltName: Full=Protein ECERIFERUM 9; AltName: Full=Protein SUPPRESSOR OF DRY2 DEFFECTS 1; Short=AtSUD1; AltName: Full=RING/U-box domain-containing protein [Arabidopsis thaliana]

Related Sequences to LMP010976 proteins

Reference Database Accession Length Protein Name
GI:186516113 EMBL CBD22149.1 1092 unnamed protein product [Arabidopsis thaliana]
GI:145352486 EMBL CBD22149.1 1092 unnamed protein product [Arabidopsis thaliana]
GI:145352486 EMBL CBD22153.1 1092 unnamed protein product [Arabidopsis thaliana]
GI:145352486 GenBank EFH45435.1 1108 protein binding protein [Arabidopsis lyrata subsp. lyrata]
GI:186516113 GenBank EFH45435.1 1108 protein binding protein [Arabidopsis lyrata subsp. lyrata]
GI:186516113 GenBank AEE86323.1 1108 cuticular wax biosynthesis protein [Arabidopsis thaliana]
GI:145352486 GenBank AEE86324.1 1107 cuticular wax biosynthesis protein [Arabidopsis thaliana]
GI:186516113 RefSeq NP_195136.3 1108 probable E3 ubiquitin ligase SUD1 [Arabidopsis thaliana]
GI:145352486 RefSeq NP_001119113.1 1107 probable E3 ubiquitin ligase SUD1 [Arabidopsis thaliana]
GI:145352486 RefSeq XP_002869176.1 1108 protein binding protein [Arabidopsis lyrata subsp. lyrata]
GI:186516113 RefSeq XP_002869176.1 1108 protein binding protein [Arabidopsis lyrata subsp. lyrata]
GI:186516113 SwissProt F4JKK0.1 1108 RecName: Full=Probable E3 ubiquitin ligase SUD1; AltName: Full=Protein ECERIFERUM 9; AltName: Full=Protein SUPPRESSOR OF DRY2 DEFFECTS 1; Short=AtSUD1; AltName: Full=RING/U-box domain-containing protein [Arabidopsis thaliana]