Gene/Proteome Database (LMPD)

LMPD ID
LMP010920
Gene ID
829232
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
Biotin/lipoate A/B protein ligase family
Gene Symbol
AT4G31050
Synonyms
F6I18.40; F6I18_40
Alternate Names
Biotin/lipoate A/B protein ligase family
Chromosome
4
EC Number
2.3.1.-

Proteins

Biotin/lipoate A/B protein ligase family
Refseq ID NP_567866
Protein GI 18417727
UniProt ID Q948J9
mRNA ID NM_119255
Length 278
RefSeq Status REVIEWED
MELLNGVETLVSGIHHHHRTNAKRNRLVRSVKILNSGNHEIPRKCLCFDLYDKLVPYKKAWSWQKSIVEEKKTLIDRNQDCADTVILLQHSPVYTMGTASTEDYLNFDIKDAPFNVYRTERGGEVTYHGPGQLVMYPIINLRNHEMDLHWYLRMLEEIVIRVLSSTFSIKASRLDGLTGVWVGNQKVAAIGIRVSKWITYHGLALNVTTDLTPFNWIVPCGIRDRKVGNIKGLLEDGEHGMVDDLRLIDIVHESLLKEFSEAFQLQIEKQTVSDPNIL

Gene Information

Entrez Gene ID
829232
Gene Name
Biotin/lipoate A/B protein ligase family
Gene Symbol
AT4G31050
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IEA:UniProtKB-KW C chloroplast
GO:0016415 IEA:InterPro F octanoyltransferase activity
GO:0006464 IEA:InterPro P cellular protein modification process
GO:0009107 IEA:InterPro P lipoate biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00785 Lipoic acid metabolism
ko00785 Lipoic acid metabolism
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY0-501 lipoate biosynthesis and incorporation I

Domain Information

InterPro Annotations

Accession Description
IPR004143 Biotin/lipoate A/B protein ligase
IPR000544 Octanoyltransferase
IPR020605 Octanoyltransferase, conserved site

UniProt Annotations

Entry Information

Gene Name
Biotin/lipoate A/B protein ligase family
Protein Entry
LIP2P_ARATH
UniProt ID
Q948J9
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Lipoyl-[acyl-carrier-protein] + apo-protein = holo-protein + acyl-carrier-protein.
Function Catalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier-protein as a source of lipoyl groups, although octanoyl groups from octanoyl-ACP can also be transferred to the lipoyl domain of apoproteins. {ECO:0000269|PubMed:11602263}.
Pathway Protein modification; protein lipoylation via endogenous pathway.
Sequence Caution Sequence=CAA18187.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31060 has been split into 2 genes: At4g31060 and At4g31050.; Evidence={ECO:0000305}; Sequence=CAB79824.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g31060 has been split into 2 genes: At4g31060 and At4g31050.; Evidence={ECO:0000305};
Similarity Belongs to the LipB family. {ECO:0000305}.
Similarity Contains 1 BPL/LPL catalytic domain. {ECO:0000255|PROSITE-ProRule:PRU01067}.
Subcellular Location Plastid, chloroplast {ECO:0000269|PubMed:11602263}.
Tissue Specificity Expressed in roots, leaves and flowers. {ECO:0000269|PubMed:11602263}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010920 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18417727 RefSeq NP_567866 278 Biotin/lipoate A/B protein ligase family

Identical Sequences to LMP010920 proteins

Reference Database Accession Length Protein Name
GI:18417727 DBBJ BAB69449.1 278 lipoyltransferase [Arabidopsis thaliana]
GI:18417727 DBBJ BAD94675.1 278 putative protein [Arabidopsis thaliana]
GI:18417727 GenBank ABD91501.1 278 At4g31050 [Arabidopsis thaliana]
GI:18417727 GenBank AEE85851.1 278 Biotin/lipoate A/B protein ligase family [Arabidopsis thaliana]
GI:18417727 SwissProt Q948J9.1 278 RecName: Full=Plastidial lipoyltransferase 2; AltName: Full=Lipoate-protein ligase 2p; AltName: Full=Lipoyl-[acyl-carrier-protein]-protein-N-lipoyltransferase 2p [Arabidopsis thaliana]

Related Sequences to LMP010920 proteins

Reference Database Accession Length Protein Name
GI:18417727 EMBL CDY23274.1 332 BnaA08g12720D [Brassica napus]
GI:18417727 GenBank EFH45607.1 288 lipoyltransferase [Arabidopsis lyrata subsp. lyrata]
GI:18417727 GenBank ESQ54089.1 280 hypothetical protein EUTSA_v10025943mg [Eutrema salsugineum]
GI:18417727 GenBank KFK29685.1 288 hypothetical protein AALP_AA7G165400 [Arabis alpina]
GI:18417727 RefSeq XP_002869348.1 288 lipoyltransferase [Arabidopsis lyrata subsp. lyrata]
GI:18417727 RefSeq XP_006412636.1 280 hypothetical protein EUTSA_v10025943mg [Eutrema salsugineum]