Gene/Proteome Database (LMPD)

LMPD ID
LMP010881
Gene ID
832609
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phospholipase D alpha 3
Gene Symbol
PLDALPHA3
Synonyms
F18G18.110; F18G18_110; phospholipase D alpha 3; PLDALPHA3
Alternate Names
phospholipase D alpha 3
Chromosome
5
EC Number
3.1.4.4

Proteins

phospholipase D alpha 3
Refseq ID NP_197919
Protein GI 15239403
UniProt ID P58766
mRNA ID NM_122446
Length 820
RefSeq Status REVIEWED
MTEQLLLHGTLEVKIYRIDKLHQRSRFNLCGKGNKEPTGKKTQSQIKRLTDSCTSLFGGHLYATIDLDRSRVARTMMRRHPKWLQSFHVYTAHSISKIIFTVKEDEPVSASLIGRAYLPVTEVITGQPIDRWLDILDENRRPIQGGSKLHVRVKFTHVTQDVNWNKGIILPSFNGVPNAYFNQREGCKVTLYQDAHVLNEYPDVTLTGGQVIYKHHRCWEEIFDAIWEAKHLIYIAGWSVNTDVTLVRDPKRTRPGGDLKLGELLKKKAEENVTVLMLVWDDRTSHEVFKRDGLMMTHDQETYDYFKNTKVRCVLCPRNPDNGDSIVQGFEVATMFTHHQKTIVVDSEVDGSLTKRRIVSFLGGIDLCDGRYDTVEHPLFGTLNSVHANDFHQPNFDGASIKKGGPREPWHDIHCKLDGPAAWDVLYNFEQRWMKQGSGRRYLISMAQLAEITVPPLPIVQPDNEEGWTVQVFRSIDDGAVEGFPEDPREAASIGLISGKDNVIERSIQDAYVNAIRRAKNFIYIENQYFLGSSFGWNSRDINLNEINALQLIPKEISLKIVSKIEAGERFSVYIVIPLWPEGKPGSASVQAILDWQRRTMEMMYTDIIIALRKKGLDANPRDYLTFFCLGNREKGKVGEYLPPEKPEANSDYARAQESRRFMIYVHSKMMIVDDEYIIIGSANINQRSMDGGRDTEIAMGAYQPSHLLSTNNMRPVGQIFSFRISLWLEHLRVTTNAFQCPESEECIRMVNATADELWGLYSAQEYPRNDDLPGHLLSYPISIGSNGEVTNLAGTEFFPDTNAKVVGEKSNYLPPILTS

Gene Information

Entrez Gene ID
832609
Gene Name
phospholipase D alpha 3
Gene Symbol
PLDALPHA3
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0070290 IEA:UniProtKB-EC F N-acylphosphatidylethanolamine-specific phospholipase D activity
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004630 IDA:TAIR F phospholipase D activity
GO:0046466 IMP:TAIR P membrane lipid catabolic process
GO:0046470 IEA:InterPro P phosphatidylcholine metabolic process
GO:0009737 IMP:TAIR P response to abscisic acid
GO:0009651 IMP:TAIR P response to salt stress
GO:0009414 IMP:TAIR P response to water deprivation

KEGG Pathway Links

KEGG Pathway ID Description
ath04144 Endocytosis
ath00565 Ether lipid metabolism
ath00564 Glycerophospholipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
6254320 Synthesis of PG

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR015679 Phospholipase D family
IPR024632 Phospholipase D, C-terminal
IPR011402 Phospholipase D, plant
IPR001736 Phospholipase D/Transphosphatidylase

UniProt Annotations

Entry Information

Gene Name
phospholipase D alpha 3
Protein Entry
PLDZ1_ARATH
UniProt ID
P58766
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A phosphatidylcholine + H(2)O = choline + a phosphatidate.
Cofactor Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250};
Domain C2 domain is a calcium-binding fold, and the binding promotes the protein association with membranes. A lower affinity toward calcium can be anticipated for PLD alpha due to the absence of two potential calcium ligands.
Function Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.
Induction Regulated by the transcription factors NAC045 and NAC086. {ECO:0000269|PubMed:25081480}.
Similarity Belongs to the phospholipase D family. C2-PLD subfamily. {ECO:0000305}.
Similarity Contains 1 C2 domain. {ECO:0000305}.
Similarity Contains 2 PLD phosphodiesterase domains. {ECO:0000255|PROSITE-ProRule:PRU00153}.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Expressed in the sieve elements. {ECO:0000269|PubMed:25081480}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010881 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15239403 RefSeq NP_197919 820 phospholipase D alpha 3

Identical Sequences to LMP010881 proteins

Reference Database Accession Length Protein Name
GI:15239403 gnl TAIR 820 phospholipase D alpha 3 [Arabidopsis thaliana]
GI:15239403 SwissProt P58766.1 820 RecName: Full=Phospholipase D zeta; Short=AtPLDzeta; Short=PLD zeta [Arabidopsis thaliana]

Related Sequences to LMP010881 proteins

Reference Database Accession Length Protein Name
GI:15239403 GenBank EFH50513.1 819 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:15239403 RefSeq XP_002874254.1 819 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:15239403 RefSeq XP_010454864.1 820 PREDICTED: phospholipase D zeta-like [Camelina sativa]
GI:15239403 RefSeq XP_010454865.1 820 PREDICTED: phospholipase D zeta-like [Camelina sativa]
GI:15239403 RefSeq XP_010493793.1 820 PREDICTED: phospholipase D zeta [Camelina sativa]
GI:15239403 RefSeq XP_010493794.1 820 PREDICTED: phospholipase D zeta [Camelina sativa]