Gene/Proteome Database (LMPD)

LMPD ID
LMP010857
Gene ID
821286
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phospholipase A(1) LCAT3
Gene Symbol
LCAT3
Synonyms
ARABIDOPSIS LECITHIN:CHOLESTEROL ACYLTRANSFERASE 3; ATLCAT3; LCAT3; lecithin:cholesterol acyltransferase 3; T21P5.27; T21P5_27
Alternate Names
phospholipase A(1) LCAT3
Chromosome
3
EC Number
3.1.1.32

Proteins

phospholipase A(1) LCAT3
Refseq ID NP_566201
Protein GI 18396510
UniProt ID Q93V61
mRNA ID NM_111202
Length 447
RefSeq Status REVIEWED
MGWIPCPCWGTNDDENAGEVADRDPVLLVSGIGGSILHSKKKNSKSEIRVWVRIFLANLAFKQSLWSLYNPKTGYTEPLDDNIEVLVPDDDHGLYAIDILDPSWFVKLCHLTEVYHFHDMIEMLVGCGYKKGTTLFGYGYDFRQSNRIDLLILGLKKKLETAYKRSGGRKVTIISHSMGGLMVSCFMYLHPEAFSKYVNKWITIATPFQGAPGCINDSILTGVQFVEGLESFFFVSRWTMHQLLVECPSIYEMMANPDFKWKKQPEIRVWRKKSENDVDTSVELESFGLIESIDLFNDALKNNELSYGGNKIALPFNFAILDWAAKTREILNKAQLPDGVSFYNIYGVSLNTPFDVCYGTETSPIDDLSEICQTMPEYTYVDGDGTVPAESAAAAQFKAVASVGVSGSHRGLLRDERVFELIQQWLGVEPKKAKRKHLRTHKVVDSG

Gene Information

Entrez Gene ID
821286
Gene Name
phospholipase A(1) LCAT3
Gene Symbol
LCAT3
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0052740 IEA:UniProtKB-EC F 1-acyl-2-lysophosphatidylserine acylhydrolase activity
GO:0008374 IEA:InterPro F O-acyltransferase activity
GO:0008970 IEA:UniProtKB-EC F phosphatidylcholine 1-acylhydrolase activity
GO:0052739 IEA:UniProtKB-EC F phosphatidylserine 1-acylhydrolase activity
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6803 phosphatidylcholine acyl editing
LIPASYN-PWY phospholipases
LIPASYN-PWY phospholipases

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
phospholipase A(1) LCAT3
Protein Entry
LCAT3_ARATH
UniProt ID
Q93V61
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties pH dependence: Optimum pH is 6.0-6.5. {ECO:0000269|PubMed:15355352}; Temperature dependence: Optimum temperature is 60 to 65 degrees Celsius. {ECO:0000269|PubMed:15355352};
Catalytic Activity Phosphatidylcholine + H(2)O = 2- acylglycerophosphocholine + a carboxylate.
Function Hydrolyzes the sn-1 acylester bond of phospholipids. Phosphatidylcholine, phosphatidylethanolamine and phosphatidic acid can be used as substrates. Weak activity with lysophosphatidylcholine and no activity with tripalmitoylglycerol and cholesteryl oleate. Seems to have a preference for unsaturated fatty acids at the sn-1 position. {ECO:0000269|PubMed:15355352}.
Miscellaneous Unaffected by calcium.
Sequence Caution Sequence=AAF01599.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:15355352}; Peripheral membrane protein {ECO:0000269|PubMed:15355352}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010857 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18396510 RefSeq NP_566201 447 phospholipase A(1) LCAT3

Identical Sequences to LMP010857 proteins

Reference Database Accession Length Protein Name
GI:18396510 GenBank AAM47477.1 447 AT3g03310/T21P5_27 [Arabidopsis thaliana]
GI:18396510 GenBank AAQ04051.1 447 phospholipase A1 [Arabidopsis thaliana]
GI:18396510 GenBank ABN27778.1 447 Sequence 9 from patent US 7157619
GI:18396510 GenBank ADA08781.1 447 Sequence 9 from patent US 7601890
GI:18396510 GenBank AEE73928.1 447 phospholipase A(1) LCAT3 [Arabidopsis thaliana]
GI:18396510 SwissProt Q93V61.1 447 RecName: Full=Phospholipase A(1) LCAT3; AltName: Full=Lecithin-cholesterol acyltransferase-like 3 [Arabidopsis thaliana]

Related Sequences to LMP010857 proteins

Reference Database Accession Length Protein Name
GI:18396510 GenBank EFH60629.1 454 lecithin:cholesterol acyltransferase family protein [Arabidopsis lyrata subsp. lyrata]
GI:18396510 GenBank EOA30564.1 448 hypothetical protein CARUB_v10013690mg [Capsella rubella]
GI:18396510 GenBank ESQ49769.1 446 hypothetical protein EUTSA_v10020730mg [Eutrema salsugineum]
GI:18396510 RefSeq XP_002884370.1 454 lecithin:cholesterol acyltransferase family protein [Arabidopsis lyrata subsp. lyrata]
GI:18396510 RefSeq XP_006297666.1 448 hypothetical protein CARUB_v10013690mg [Capsella rubella]
GI:18396510 RefSeq XP_006408316.1 446 hypothetical protein EUTSA_v10020730mg [Eutrema salsugineum]