Gene/Proteome Database (LMPD)

LMPD ID
LMP010749
Gene ID
827142
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
pentatricopeptide repeat-containing protein LOI1
Gene Symbol
LOI1
Synonyms
DL3465W; FCAALL.335; LOI1; lovastatin insensitive 1; MEF11
Alternate Names
pentatricopeptide repeat-containing protein LOI1
Chromosome
4
Summary
Encodes a pentatricopeptide (PPR) protein that binds single-stranded RNA. The N-terminal portion of the protein can localize to the mitochondria. Mutations in this gene make plants less sensitive to inhibitors of the MEP and MVA pathways of isoprenoid biosynthesis and increase the activity of HMG CoA reductase.
Orthologs
View orthologs and multiple alignments for LOI1

Proteins

pentatricopeptide repeat-containing protein LOI1
Refseq ID NP_193221
Protein GI 79475105
UniProt ID Q0WSH6
mRNA ID NM_117571
Length 684
RefSeq Status REVIEWED
MSLLSADALGLLLKNAISASSMRLGRVVHARIVKTLDSPPPPFLANYLINMYSKLDHPESARLVLRLTPARNVVSWTSLISGLAQNGHFSTALVEFFEMRREGVVPNDFTFPCAFKAVASLRLPVTGKQIHALAVKCGRILDVFVGCSAFDMYCKTRLRDDARKLFDEIPERNLETWNAFISNSVTDGRPREAIEAFIEFRRIDGHPNSITFCAFLNACSDWLHLNLGMQLHGLVLRSGFDTDVSVCNGLIDFYGKCKQIRSSEIIFTEMGTKNAVSWCSLVAAYVQNHEDEKASVLYLRSRKDIVETSDFMISSVLSACAGMAGLELGRSIHAHAVKACVERTIFVGSALVDMYGKCGCIEDSEQAFDEMPEKNLVTRNSLIGGYAHQGQVDMALALFEEMAPRGCGPTPNYMTFVSLLSACSRAGAVENGMKIFDSMRSTYGIEPGAEHYSCIVDMLGRAGMVERAYEFIKKMPIQPTISVWGALQNACRMHGKPQLGLLAAENLFKLDPKDSGNHVLLSNTFAAAGRWAEANTVREELKGVGIKKGAGYSWITVKNQVHAFQAKDRSHILNKEIQTTLAKLRNEMEAAGYKPDLKLSLYDLEEEEKAAEVSHHSEKLALAFGLLSLPLSVPIRITKNLRICGDCHSFFKFVSGSVKREIIVRDNNRFHRFKDGICSCKDYW

Gene Information

Entrez Gene ID
827142
Gene Name
pentatricopeptide repeat-containing protein LOI1
Gene Symbol
LOI1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:TAIR C mitochondrion
GO:0000166 IEA:UniProtKB-KW F nucleotide binding
GO:0034046 IDA:TAIR F poly(G) binding
GO:0019288 IMP:TAIR P isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0019287 IMP:TAIR P isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0050790 IMP:TAIR P regulation of catalytic activity
GO:0048364 IMP:TAIR P root development
GO:0016125 IMP:TAIR P sterol metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR002885 Pentatricopeptide repeat
IPR011990 Tetratricopeptide-like helical domain

UniProt Annotations

Entry Information

Gene Name
pentatricopeptide repeat-containing protein LOI1
Protein Entry
PP312_ARATH
UniProt ID
Q0WSH6
Species
Arabidopsis

Comments

Comment Type Description
Function Acts as a regulatory factor of isoprenoid biosynthesis. Could bind RNA. {ECO:0000269|PubMed:17213228}.
Sequence Caution Sequence=CAB10264.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB78527.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
Similarity Contains 14 PPR (pentatricopeptide) repeats. {ECO:0000255|PROSITE-ProRule:PRU00708}.
Web Resource Name=Arabidopsis PPR Protein Database; URL="http://www.plantenergy.uwa.edu.au/applications/ppr/ppr.php";

Identical and Related Proteins

Unique RefSeq proteins for LMP010749 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
79475105 RefSeq NP_193221 684 pentatricopeptide repeat-containing protein LOI1

Identical Sequences to LMP010749 proteins

Reference Database Accession Length Protein Name
GI:79475105 DBBJ BAE99922.1 684 hypothetical protein [Arabidopsis thaliana]
GI:79475105 GenBank AEE83509.1 684 pentatricopeptide repeat-containing protein [Arabidopsis thaliana]
GI:79475105 SwissProt Q0WSH6.1 684 RecName: Full=Pentatricopeptide repeat-containing protein At4g14850; AltName: Full=Protein LOVASTATIN INSENSITIVE 1 [Arabidopsis thaliana]

Related Sequences to LMP010749 proteins

Reference Database Accession Length Protein Name
GI:79475105 GenBank AAQ65087.1 634 At4g14850 [Arabidopsis thaliana]
GI:79475105 GenBank EOA16145.1 684 hypothetical protein CARUB_v10004282mg [Capsella rubella]
GI:79475105 RefSeq XP_006283247.1 684 hypothetical protein CARUB_v10004282mg [Capsella rubella]
GI:79475105 RefSeq XP_010435060.1 684 PREDICTED: pentatricopeptide repeat-containing protein At4g14850-like [Camelina sativa]
GI:79475105 RefSeq XP_010440383.1 684 PREDICTED: pentatricopeptide repeat-containing protein At4g14850 [Camelina sativa]
GI:79475105 RefSeq XP_010449981.1 684 PREDICTED: pentatricopeptide repeat-containing protein At4g14850-like isoform X2 [Camelina sativa]