Gene/Proteome Database (LMPD)

LMPD ID
LMP010721
Gene ID
831841
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
oxysterol-binding protein-related protein 3A
Gene Symbol
UNE18
Synonyms
ORP3A; OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3A; T7H20.150; T7H20_150; UNE18; UNFERTILIZED EMBRYO SAC 18
Alternate Names
oxysterol-binding protein-related protein 3A
Chromosome
5

Proteins

oxysterol-binding protein-related protein 3A
Refseq ID NP_195830
Protein GI 15241681
UniProt ID Q9LZM1
mRNA ID NM_120288
Length 453
RefSeq Status REVIEWED
MASNDPKNGGGFFASLASSITNFGSAMSKSVNGLMGYEGLEVINPEGSTDDAEEEAGRGRWKQEERDGYWKMMQKYIGSDVTSMVTLPVIIFEPMTMLQKMAELMEYSYLLDMADKTEDPYMRMVYASSWAISVYYAYQRTWKPFNPILGETYEMTNHNGINFIAEQVCHHPPMSAGHAENEHFAYDCTSKLKTKFLGNSIDVYPVGRTRVTLKRDGVVLDLVPPLTKVHNLIFGRTWVDSPGEMVMTNLTTGDKVVLYFQPCGWFGSGRYEVDGYVYNSAEEPKMLMTGKWNESLSYQPCDAEGEPLPGTELKEVWKVAEAPKNDKYQYTHFAHKINSFDTAPKKLLSSDSRLRPDRYALEMGDMSKSGFEKSSLEDRQRAEKKSREEKGQKFAPKWFDETEEVTPTPWGDLEVYQFNGKYSVHRATAENSEDTTDVKLTQFNPWQFQDLSA

Gene Information

Entrez Gene ID
831841
Gene Name
oxysterol-binding protein-related protein 3A
Gene Symbol
UNE18
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0032934 IDA:TAIR F sterol binding
GO:0009567 IMP:TAIR P double fertilization forming a zygote and endosperm
GO:0006869 IEA:UniProtKB-KW P lipid transport
GO:0007338 IEA:UniProtKB-KW P single fertilization

Domain Information

InterPro Annotations

Accession Description
IPR000648 Oxysterol-binding protein
IPR018494 Oxysterol-binding protein, conserved site

UniProt Annotations

Entry Information

Gene Name
oxysterol-binding protein-related protein 3A
Protein Entry
ORP3A_ARATH
UniProt ID
Q9LZM1
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype Unfertilized ovules, but normal pollen tube attraction. {ECO:0000269|PubMed:15634699}.
Function Oxysterol-binding protein that may be involved in the transport of sterols between the ER and the Golgi. Binds beta- sitosterol. Required for ovule fertilization. {ECO:0000269|PubMed:15634699, ECO:0000269|PubMed:19207211}.
Interaction Q9SHC8:PVA12; NbExp=3; IntAct=EBI-2292648, EBI-2292633;
Similarity Belongs to the OSBP family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:19207211}. Golgi apparatus {ECO:0000269|PubMed:19207211}. Note=Interaction with PVA12 is necessary for targeting to the ER. Located in the Golgi in the absence of interaction with PVA12.
Subunit Interacts with PVA12. {ECO:0000269|PubMed:19207211}.
Tissue Specificity Expressed in roots, leaves, stems, flowers and pollen. {ECO:0000269|PubMed:16897474}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010721 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15241681 RefSeq NP_195830 453 oxysterol-binding protein-related protein 3A

Identical Sequences to LMP010721 proteins

Reference Database Accession Length Protein Name
GI:15241681 EMBL CAB82983.1 453 putative protein [Arabidopsis thaliana]
GI:15241681 GenBank AAK92774.1 453 unknown protein [Arabidopsis thaliana]
GI:15241681 GenBank AAM14105.1 453 putative oxysterol-binding protein [Arabidopsis thaliana]
GI:15241681 gnl TAIR 453 oxysterol-binding protein-related protein 3A [Arabidopsis thaliana]
GI:15241681 SwissProt Q9LZM1.1 453 RecName: Full=Oxysterol-binding protein-related protein 3A; AltName: Full=OSBP-related protein 3A; AltName: Full=Protein UNFERTILIZED EMBRYO SAC 18 [Arabidopsis thaliana]

Related Sequences to LMP010721 proteins

Reference Database Accession Length Protein Name
GI:15241681 GenBank EFH47210.1 453 hypothetical protein ARALYDRAFT_324883 [Arabidopsis lyrata subsp. lyrata]
GI:15241681 GenBank EOA20623.1 453 hypothetical protein CARUB_v10000934mg [Capsella rubella]
GI:15241681 RefSeq XP_002870951.1 453 hypothetical protein ARALYDRAFT_324883 [Arabidopsis lyrata subsp. lyrata]
GI:15241681 RefSeq XP_006287725.1 453 hypothetical protein CARUB_v10000934mg [Capsella rubella]
GI:15241681 RefSeq XP_009146938.1 454 PREDICTED: oxysterol-binding protein-related protein 3B [Brassica rapa]
GI:15241681 RefSeq XP_010490625.1 453 PREDICTED: oxysterol-binding protein-related protein 3A [Camelina sativa]