Gene/Proteome Database (LMPD)

LMPD ID
LMP010584
Gene ID
835806
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
lycopene epsilon cyclase
Gene Symbol
LUT2
Synonyms
LUTEIN DEFICIENT 2; LYCOPENE EPSILON-CYCLASE
Alternate Names
lycopene epsilon cyclase
Chromosome
5
EC Number
5.5.1.18

Proteins

lycopene epsilon cyclase
Refseq ID NP_200513
Protein GI 15242019
UniProt ID Q38932
mRNA ID NM_125085
Length 524
RefSeq Status REVIEWED
MECVGARNFAAMAVSTFPSWSCRRKFPVVKRYSYRNIRFGLCSVRASGGGSSGSESCVAVREDFADEEDFVKAGGSEILFVQMQQNKDMDEQSKLVDKLPPISIGDGALDLVVIGCGPAGLALAAESAKLGLKVGLIGPDLPFTNNYGVWEDEFNDLGLQKCIEHVWRETIVYLDDDKPITIGRAYGRVSRRLLHEELLRRCVESGVSYLSSKVDSITEASDGLRLVACDDNNVIPCRLATVASGAASGKLLQYEVGGPRVCVQTAYGVEVEVENSPYDPDQMVFMDYRDYTNEKVRSLEAEYPTFLYAMPMTKSRLFFEETCLASKDVMPFDLLKTKLMLRLDTLGIRILKTYEEEWSYIPVGGSLPNTEQKNLAFGAAASMVHPATGYSVVRSLSEAPKYASVIAEILREETTKQINSNISRQAWDTLWPPERKRQRAFFLFGLALIVQFDTEGIRSFFRTFFRLPKWMWQGFLGSTLTSGDLVLFALYMFVISPNNLRKGLINHLISDPTGATMIKTYLKV

Gene Information

Entrez Gene ID
835806
Gene Name
lycopene epsilon cyclase
Gene Symbol
LUT2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IEA:UniProtKB-KW C chloroplast
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0045435 TAS:TAIR F lycopene epsilon cyclase activity
GO:0016705 IEA:InterPro F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016117 IMP:TAIR P carotenoid biosynthetic process
GO:0016123 IGI:TAIR P xanthophyll biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath00906 Carotenoid biosynthesis
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
CAROTENOID-PWY superpathway of carotenoid biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR010108 Lycopene cyclase, beta/epsilon
IPR008671 Lycopene cyclase-type, FAD-binding

UniProt Annotations

Entry Information

Gene Name
lycopene epsilon cyclase
Protein Entry
LCYE_ARATH
UniProt ID
Q38932
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Carotenoid psi-end group = carotenoid epsilon- end group. {ECO:0000269|PubMed:11226339}.
Function Catalyzes the single epsilon-cyclization reaction which converts lycopene to delta-carotene and neurosporene to alpha- zeacarotene. Required for lutein biosynthesis.
Pathway Carotenoid biosynthesis; alpha-zeacarotene biosynthesis.
Pathway Carotenoid biosynthesis; delta-carotene biosynthesis.
Similarity Belongs to the lycopene cyclase family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP010584 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15242019 RefSeq NP_200513 524 lycopene epsilon cyclase

Identical Sequences to LMP010584 proteins

Reference Database Accession Length Protein Name
GI:15242019 EMBL CAG26500.1 524 unnamed protein product [Arabidopsis thaliana]
GI:15242019 GenBank ADT60422.1 524 Sequence 1734 from patent US 7847156
GI:15242019 GenBank AFX01478.1 524 Sequence 19 from patent US 8277849
GI:15242019 GenBank AFX17199.1 524 Sequence 19 from patent US 8298548
GI:15242019 gnl TAIR 524 lycopene epsilon cyclase [Arabidopsis thaliana]
GI:15242019 SwissProt Q38932.2 524 RecName: Full=Lycopene epsilon cyclase, chloroplastic; AltName: Full=Protein LUTEIN DEFICIENT 2; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010584 proteins

Reference Database Accession Length Protein Name
GI:15242019 GenBank AAB53336.1 524 lycopene epsilon cyclase [Arabidopsis thaliana]
GI:15242019 GenBank AAR75800.1 524 Sequence 2 from patent US 6642021
GI:15242019 GenBank AAR75813.1 524 Sequence 21 from patent US 6642021
GI:15242019 GenBank AAR75830.1 524 Sequence 49 from patent US 6642021
GI:15242019 pat US 524 Sequence 2 from patent US 5744341
GI:15242019 pat US 524 Sequence 21 from patent US 5744341