Gene/Proteome Database (LMPD)

LMPD ID
LMP010563
Gene ID
842748
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
long-chain acyl-CoA synthetase
Gene Symbol
LACS3
Synonyms
F15H21.7; F15H21_7; LACS3; long-chain acyl-CoA synthetase 3
Alternate Names
long-chain acyl-CoA synthetase
Chromosome
1
EC Number
6.2.1.3

Proteins

long-chain acyl-CoA synthetase
Refseq ID NP_176622
Protein GI 15217631
UniProt ID Q9C7W4
mRNA ID NM_105115
Length 665
RefSeq Status REVIEWED
MATGRYIVEVEKGKQGVDGGSPSVGPVYRSIYAKDGFPEPPDDLVSAWDIFRLSVEKSPNNPMLGRREIVDGKAGKYVWQTYKEVHNVVIKLGNSIRTIGVGKGDKCGIYGANSPEWIISMEACNAHGLYCVPLYDTLGAGAIEFIICHAEVSLAFAEENKISELLKTAPKSTKYLKYIVSFGEVTNNQRVEAERHRLTIYSWDQFLKLGEGKHYELPEKRRSDVCTIMYTSGTTGDPKGVLLTNESIIHLLEGVKKLLKTIDEELTSKDVYLSYLPLAHIFDRVIEELCIYEAASIGFWRGDVKILIEDIAALKPTVFCAVPRVLERIYTGLQQKLSDGGFVKKKLFNFAFKYKHKNMEKGQPHEQASPIADKIVFKKVKEGLGGNVRLILSGAAPLAAHIESFLRVVACAHVLQGYGLTESCGGTFVSIPNELSMLGTVGPPVPNVDIRLESVPEMGYDALASNPRGEICIRGKTLFSGYYKREDLTQEVFIDGWLHTGDVGEWQPDGAMKIIDRKKNIFKLSQGEYVAVENLENIYSHVAAIESIWVYGNSYESYLVAVVCPSKIQIEHWAKEHKVSGDFESICRNQKTKEFVLGEFNRVAKDKKLKGFELIKGVHLDTVPFDMERDLITPSYKMKRPQLLKYYQKEIDEMYKKNREVQLRV

Gene Information

Entrez Gene ID
842748
Gene Name
long-chain acyl-CoA synthetase
Gene Symbol
LACS3
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004467 IDA:UniProtKB F long-chain fatty acid-CoA ligase activity
GO:0006631 TAS:UniProtKB P fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00061 Fatty acid biosynthesis
ath00071 Fatty acid degradation
ath04146 Peroxisome
ath_M00086 beta-Oxidation, acyl-CoA synthesis

Domain Information

InterPro Annotations

Accession Description
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
long-chain acyl-CoA synthetase
Protein Entry
LACS3_ARATH
UniProt ID
Q9C7W4
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. {ECO:0000269|PubMed:12177484}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate.
Pathway Lipid metabolism; fatty acid metabolism.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010563 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15217631 RefSeq NP_176622 665 long-chain acyl-CoA synthetase

Identical Sequences to LMP010563 proteins

Reference Database Accession Length Protein Name
GI:15217631 EMBL CBF64930.1 665 unnamed protein product [Arabidopsis thaliana]
GI:15217631 EMBL CBU89801.1 665 unnamed protein product [Arabidopsis thaliana]
GI:15217631 GenBank ABJ40757.1 665 Sequence 14 from patent US 7105722
GI:15217631 GenBank ADT60391.1 665 Sequence 1672 from patent US 7847156
GI:15217631 GenBank AEE34237.1 665 long-chain acyl-CoA synthetase [Arabidopsis thaliana]
GI:15217631 GenBank AGX56830.1 665 Sequence 13979 from patent US 8541208

Related Sequences to LMP010563 proteins

Reference Database Accession Length Protein Name
GI:15217631 GenBank EFH62604.1 663 hypothetical protein ARALYDRAFT_474909 [Arabidopsis lyrata subsp. lyrata]
GI:15217631 GenBank EOA33728.1 660 hypothetical protein CARUB_v10019918mg [Capsella rubella]
GI:15217631 GenBank ESQ28906.1 660 hypothetical protein EUTSA_v10023330mg [Eutrema salsugineum]
GI:15217631 RefSeq XP_002886345.1 663 hypothetical protein ARALYDRAFT_474909 [Arabidopsis lyrata subsp. lyrata]
GI:15217631 RefSeq XP_006300830.1 660 hypothetical protein CARUB_v10019918mg [Capsella rubella]
GI:15217631 RefSeq XP_006391620.1 660 hypothetical protein EUTSA_v10023330mg [Eutrema salsugineum]