Gene/Proteome Database (LMPD)

LMPD ID
LMP010523
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
LAG1 longevity assurance-1
Gene Symbol
Synonyms
LAG1 HOMOLOG 1; LONGEVITY ASSURANCE GENE 1
Alternate Names
LAG1 longevity assurance-1
Chromosome
3
Summary
LAG1 homolog 1
Orthologs

Proteins

LAG1 longevity assurance-1
Refseq ID NP_566769
Protein GI 18404559
UniProt ID Q9LDF2
mRNA ID NM_113450
Length 310
RefSeq Status REVIEWED
MGLFESVKSIDWEQESFPTYQDLGFLPLFAVFFPTIRFLLDRFVFEKLASLVIYGRMSTNKSDNIKDRKKNSPKVRKFKESAWKCIYYLSAELLALSVTYNEPWFSNTLYFWIGPGDQIWPDQPMKMKLKFLYMFAAGFYTYSIFALVFWETRRSDFGVSMGHHITTLVLIVLSYICRLTRAGSVILALHDASDVFLEIGKMSKYCGAESLASISFVLFALSWVVLRLIYYPFWILWSTSYQIIMTVDKEKHPNGPILYYMFNTLLYFLLVLHIFWWVLIYRMLVKQVQDRGKLSEDVRSDSESDDEHED

Gene Information

Entrez Gene ID
Gene Name
LAG1 longevity assurance-1
Gene Symbol
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:TAIR C plasma membrane
GO:0050291 IGI:TAIR F sphingosine N-acyltransferase activity
GO:0042761 IGI:TAIR P very long-chain fatty acid biosynthetic process

REACTOME Pathway Links

REACTOME Pathway ID Description
6253653 Metabolism
6253725 Metabolism of lipids and lipoproteins
6254191 Sphingolipid de novo biosynthesis
6254192 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR016439 Longevity assurance, LAG1/LAC1
IPR006634 TRAM/LAG1/CLN8 homology domain

UniProt Annotations

Entry Information

Gene Name
LAG1 longevity assurance-1
Protein Entry
LAG11_ARATH
UniProt ID
Species
Arabidopsis

Comments

Comment Type Description
Function Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis. Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity). {ECO:0000250}.
Similarity Contains 1 TLC (TRAM/LAG1/CLN8) domain. {ECO:0000255|PROSITE-ProRule:PRU00205}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010523 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18404559 RefSeq NP_566769 310 LAG1 longevity assurance-1

Identical Sequences to LMP010523 proteins

Reference Database Accession Length Protein Name
GI:18404559 DBBJ BAB01323.1 310 unnamed protein product [Arabidopsis thaliana]
GI:18404559 GenBank AAF66102.1 310 LAG1 homolog 1 [Arabidopsis thaliana]
GI:18404559 GenBank AAK25862.1 310 unknown protein [Arabidopsis thaliana]
GI:18404559 GenBank AAN13166.1 310 unknown protein [Arabidopsis thaliana]
GI:18404559 GenBank AEE77023.1 310 LAG1 longevity assurance-1 [Arabidopsis thaliana]
GI:18404559 SwissProt Q9LDF2.1 310 RecName: Full=LAG1 longevity assurance homolog 1; Short=LAG1 homolog 1 [Arabidopsis thaliana]

Related Sequences to LMP010523 proteins

Reference Database Accession Length Protein Name
GI:18404559 GenBank EOA24427.1 311 hypothetical protein CARUB_v10017681mg [Capsella rubella]
GI:18404559 RefSeq XP_006291529.1 311 hypothetical protein CARUB_v10017681mg [Capsella rubella]
GI:18404559 RefSeq XP_006395650.1 311 hypothetical protein EUTSA_v10004641mg [Eutrema salsugineum]
GI:18404559 RefSeq XP_010502423.1 311 PREDICTED: LAG1 longevity assurance homolog 1-like [Camelina sativa]
GI:18404559 RefSeq XP_010514167.1 311 PREDICTED: LAG1 longevity assurance homolog 1 [Camelina sativa]
GI:18404559 RefSeq XP_010425194.1 311 PREDICTED: LAG1 longevity assurance homolog 1-like [Camelina sativa]