Gene/Proteome Database (LMPD)

LMPD ID
LMP010459
Gene ID
830002
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
geranylgeranyl reductase
Gene Symbol
GGR
Synonyms
geranylgeranyl reductase; GGR
Alternate Names
geranylgeranyl reductase
Chromosome
4

Proteins

geranylgeranyl reductase
Refseq ID NP_195558
Protein GI 15233848
UniProt ID Q39108
mRNA ID NM_120007
Length 326
RefSeq Status REVIEWED
MLFSGSAIPLSSFCSLPEKPHTLPMKLSPAAIRSSSSSAPGSLNFDLRTYWTTLITEINQKLDEAIPVKHPAGIYEAMRYSVLAQGAKRAPPVMCVAACELFGGDRLAAFPTACALEMVHAASLIHDDLPCMDDDPVRRGKPSNHTVYGSGMAILAGDALFPLAFQHIVSHTPPDLVPRATILRLITEIARTVGSTGMAAGQYVDLEGGPFPLSFVQEKKFGAMGECSAVCGGLLGGATEDELQSLRRYGRAVGMLYQVVDDITEDKKKSYDGGAEKGMMEMAEELKEKAKKELQVFDNKYGGGDTLVPLYTFVDYAAHRHFLLPL

Gene Information

Entrez Gene ID
830002
Gene Name
geranylgeranyl reductase
Gene Symbol
GGR
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0008299 IEA:InterPro P isoprenoid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath01100 Metabolic pathways
ath00900 Terpenoid backbone biosynthesis
ko00900 Terpenoid backbone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR008949 Isoprenoid synthase domain
IPR000092 Polyprenyl synthetase
IPR017446 Polyprenyl synthetase-related

UniProt Annotations

Entry Information

Gene Name
geranylgeranyl reductase
Protein Entry
GGR_ARATH
UniProt ID
Q39108
Species
Arabidopsis

Comments

Comment Type Description
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 3 Mg(2+) ions per subunit. {ECO:0000250};
Function Heterodimeric geranyl(geranyl)-diphosphate (GPP) synthase small subunit. The small subunit alone is inactive in vitro while the large subunit GGPPS1 catalyzes mainly the production of geranygeranyl-diphosphate in vitro. Upon association of the two subunits, the product profile changes and the production of gerany-diphosphate is strongly increased. {ECO:0000269|PubMed:19482937}.
Similarity Belongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast {ECO:0000305}.
Subunit Part of a heterodimeric geranyl(geranyl)diphosphate synthase. Interacts with GGPPS1 or GGPPS2, but not with GGPPS9. {ECO:0000269|PubMed:19482937}.
Tissue Specificity Expressed ubiquitously. {ECO:0000269|PubMed:10759500}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010459 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15233848 RefSeq NP_195558 326 geranylgeranyl reductase

Identical Sequences to LMP010459 proteins

Reference Database Accession Length Protein Name
GI:15233848 GenBank AAM63877.1 326 geranylgeranyl pyrophosphate synthase-related protein [Arabidopsis thaliana]
GI:15233848 GenBank AAY01546.1 326 Sequence 46 from patent US 6855868
GI:15233848 GenBank ABS92546.1 326 Sequence 46 from patent US 7199283
GI:15233848 GenBank ABT05597.1 326 Sequence 46 from patent US 7217862
GI:15233848 GenBank AEE86930.1 326 geranylgeranyl reductase [Arabidopsis thaliana]
GI:15233848 SwissProt Q39108.2 326 RecName: Full=Heterodimeric geranylgeranyl pyrophosphate synthase small subunit, chloroplastic; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010459 proteins

Reference Database Accession Length Protein Name
GI:15233848 EMBL CBF64678.1 326 unnamed protein product [Arabidopsis thaliana]
GI:15233848 EMBL CBU89554.1 326 unnamed protein product [Arabidopsis thaliana]
GI:15233848 GenBank AAA81879.1 326 geranylgeranyl pyrophosphate synthase-related protein [Arabidopsis thaliana]
GI:15233848 GenBank AAG40013.1 326 AT4g38460 [Arabidopsis thaliana]
GI:15233848 GenBank AGX56556.1 326 Sequence 13450 from patent US 8541208
GI:15233848 RefSeq XP_002866799.1 310 hypothetical protein ARALYDRAFT_912293 [Arabidopsis lyrata subsp. lyrata]