Gene/Proteome Database (LMPD)

LMPD ID
LMP010414
Gene ID
820316
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
glycerol-3-phosphate acyltransferase 5
Gene Symbol
GPAT5
Synonyms
ATGPAT5; glycerol-3-phosphate acyltransferase 5; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 5; GPAT5
Alternate Names
glycerol-3-phosphate acyltransferase 5
Chromosome
3
EC Number
2.3.1.15
Summary
Encodes a protein with glycerol-3-phosphate acyltransferase activity, involved in the biosynthesis of suberin polyester.
Orthologs
View orthologs and multiple alignments for GPAT5

Proteins

glycerol-3-phosphate acyltransferase 5
Refseq ID NP_187750
Protein GI 15229747
UniProt ID Q9CAY3
mRNA ID NM_111976
Length 502
RefSeq Status REVIEWED
MVMEQAGTTSYSVVSEFEGTILKNADSFSYFMLVAFEAAGLIRFAILLFLWPVITLLDVFSYKNAALKLKIFVATVGLREPEIESVARAVLPKFYMDDVSMDTWRVFSSCKKRVVVTRMPRVMVERFAKEHLRADEVIGTELIVNRFGFVTGLIRETDVDQSALNRVANLFVGRRPQLGLGKPALTASTNFLSLCEEHIHAPIPENYNHGDQQLQLRPLPVIFHDGRLVKRPTPATALIILLWIPFGIILAVIRIFLGAVLPLWATPYVSQIFGGHIIVKGKPPQPPAAGKSGVLFVCTHRTLMDPVVLSYVLGRSIPAVTYSISRLSEILSPIPTVRLTRIRDVDAAKIKQQLSKGDLVVCPEGTTCREPFLLRFSALFAELTDRIVPVAMNYRVGFFHATTARGWKGLDPIFFFMNPRPVYEITFLNQLPMEATCSSGKSPHDVANYVQRILAATLGFECTNFTRKDKYRVLAGNDGTVSYLSLLDQLKKVVSTFEPCLH

Gene Information

Entrez Gene ID
820316
Gene Name
glycerol-3-phosphate acyltransferase 5
Gene Symbol
GPAT5
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0090447 IDA:TAIR F glycerol-3-phosphate 2-O-acyltransferase activity
GO:0004366 IEA:UniProtKB-EC F glycerol-3-phosphate O-acyltransferase activity
GO:0016024 IEA:UniProtKB-UniPathway P CDP-diacylglycerol biosynthetic process
GO:0010345 IMP:TAIR P suberin biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath00564 Glycerophospholipid metabolism
ath01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
glycerol-3-phosphate acyltransferase 5
Protein Entry
GPAT5_ARATH
UniProt ID
Q9CAY3
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: Vmax=86.85 pmol/min/mg enzyme {ECO:0000269|PubMed:12897259};
Catalytic Activity Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1- acyl-sn-glycerol 3-phosphate. {ECO:0000269|PubMed:12897259}.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
Function Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
Similarity Belongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Weakly or not expressed in roots, leaves, seedlings, developing siliques and flower buds. {ECO:0000269|PubMed:12897259}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010414 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15229747 RefSeq NP_187750 502 glycerol-3-phosphate acyltransferase 5

Identical Sequences to LMP010414 proteins

Reference Database Accession Length Protein Name
GI:15229747 DBBJ BAC42290.1 502 unknown protein [Arabidopsis thaliana]
GI:15229747 GenBank AAG51432.1 502 unknown protein; 38446-40213 [Arabidopsis thaliana]
GI:15229747 GenBank AAO50667.1 502 unknown protein [Arabidopsis thaliana]
GI:15229747 GenBank ACX15538.1 502 Sequence 42342 from patent US 7569389
GI:15229747 GenBank AEE75046.1 502 glycerol-3-phosphate acyltransferase 5 [Arabidopsis thaliana]
GI:15229747 SwissProt Q9CAY3.1 502 RecName: Full=Glycerol-3-phosphate acyltransferase 5; Short=AtGPAT5 [Arabidopsis thaliana]

Related Sequences to LMP010414 proteins

Reference Database Accession Length Protein Name
GI:15229747 GenBank ACX15537.1 515 Sequence 42341 from patent US 7569389
GI:15229747 GenBank ACX15539.1 500 Sequence 42343 from patent US 7569389
GI:15229747 GenBank EFH58990.1 502 glycerol-3-phosphate acyltransferase 5 [Arabidopsis lyrata subsp. lyrata]
GI:15229747 RefSeq XP_002882731.1 502 glycerol-3-phosphate acyltransferase 5 [Arabidopsis lyrata subsp. lyrata]
GI:15229747 RefSeq XP_010464845.1 502 PREDICTED: glycerol-3-phosphate acyltransferase 5-like [Camelina sativa]
GI:15229747 RefSeq XP_010486795.1 502 PREDICTED: glycerol-3-phosphate acyltransferase 5 [Camelina sativa]