Gene/Proteome Database (LMPD)

LMPD ID
LMP010352
Gene ID
822957
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
geranylgeranyl pyrophosphate synthase 12
Gene Symbol
AT3G32040
Alternate Names
geranylgeranyl pyrophosphate synthase 12
Chromosome
3
EC Number
2.5.1.-

Proteins

geranylgeranyl pyrophosphate synthase 12
Refseq ID NP_189747
Protein GI 15232010
UniProt ID Q9LHR4
mRNA ID NM_114027
Length 360
RefSeq Status REVIEWED
MANTVHLSSSSLFIQTRGRKYNSILSFNNLQKRTVLSLSCALTSQGGKDMIPPKGKSNDRNFAFDFKSYMIRKAESVSMALNVSVPPQDPLAIQEAVRYSLLAGGKRVRPLLCIAACELVGGDEATAMSAACAVEMIHTSSLIHDDLPCMDDADLRRGKPTNHKVFGEHMAVLAGDALLALAFEHMTVVSSGLVAPERMIRSVTELAKAIGTKGLVAGQVSDLCSQGLNPYDVGLERLEFIHLHKTAALLEAAAVLGAIIGGGTEEEIQKLRKYGRCIGLLFQVVDDIIDVTESTEELGKTAGKDVMARKLTYPRLIGLERSREVAEKLRREAAEQLLGFDSNKVAPLVALASYIACRHN

Gene Information

Entrez Gene ID
822957
Gene Name
geranylgeranyl pyrophosphate synthase 12
Gene Symbol
AT3G32040
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IEA:UniProtKB-KW C chloroplast
GO:0004161 IEA:UniProtKB-EC F dimethylallyltranstransferase activity
GO:0004311 IEA:UniProtKB-EC F farnesyltranstransferase activity
GO:0004337 IEA:UniProtKB-EC F geranyltranstransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0016117 IEA:UniProtKB-KW P carotenoid biosynthetic process
GO:0045337 IEA:UniProtKB-UniPathway P farnesyl diphosphate biosynthetic process
GO:0033384 IEA:UniProtKB-UniPathway P geranyl diphosphate biosynthetic process
GO:0033386 IEA:UniProtKB-UniPathway P geranylgeranyl diphosphate biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath01100 Metabolic pathways
ath00900 Terpenoid backbone biosynthesis
ko00900 Terpenoid backbone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR008949 Isoprenoid synthase domain
IPR000092 Polyprenyl synthetase
IPR017446 Polyprenyl synthetase-related

UniProt Annotations

Entry Information

Gene Name
geranylgeranyl pyrophosphate synthase 12
Protein Entry
GGPPC_ARATH
UniProt ID
Q9LHR4
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
Catalytic Activity Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
Catalytic Activity Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 3 Mg(2+) ions per subunit. {ECO:0000250};
Function Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate. {ECO:0000250}.
Pathway Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
Similarity Belongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast {ECO:0000305}.
Subunit Monomer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010352 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15232010 RefSeq NP_189747 360 geranylgeranyl pyrophosphate synthase 12

Identical Sequences to LMP010352 proteins

Reference Database Accession Length Protein Name
GI:15232010 EMBL CBF64795.1 360 unnamed protein product [Arabidopsis thaliana]
GI:15232010 EMBL CBU89666.1 360 unnamed protein product [Arabidopsis thaliana]
GI:15232010 GenBank AAT71982.1 360 At3g32040 [Arabidopsis thaliana]
GI:15232010 GenBank AEE77681.1 360 geranylgeranyl pyrophosphate synthase 12 [Arabidopsis thaliana]
GI:15232010 GenBank AGX56668.1 360 Sequence 13674 from patent US 8541208
GI:15232010 SwissProt Q9LHR4.1 360 RecName: Full=Geranylgeranyl pyrophosphate synthase 12, chloroplastic; Short=GGPP synthase 12; Short=GGPS12; AltName: Full=(2E,6E)-farnesyl diphosphate synthase 12; AltName: Full=Dimethylallyltranstransferase 12; AltName: Full=Farnesyl diphosphate synthase 12; AltName: Full=Farnesyltranstransferase 12; AltName: Full=Geranyltranstransferase 12; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010352 proteins

Reference Database Accession Length Protein Name
GI:15232010 DBBJ BAB02589.1 357 geranylgeranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15232010 DBBJ BAD94520.1 360 geranylgeranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15232010 GenBank AAY78760.1 357 putative geranylgeranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15232010 GenBank AEE77583.1 357 geranylgeranyl pyrophosphate synthase 11 [Arabidopsis thaliana]
GI:15232010 RefSeq NP_189589.1 357 geranylgeranyl pyrophosphate synthase 11 [Arabidopsis thaliana]
GI:15232010 SwissProt Q9LIA0.1 357 RecName: Full=Geranylgeranyl pyrophosphate synthase 11, chloroplastic; Short=GGPP synthase 11; Short=GGPS11; AltName: Full=(2E,6E)-farnesyl diphosphate synthase 11; AltName: Full=Dimethylallyltranstransferase 11; AltName: Full=Farnesyl diphosphate synthase 11; AltName: Full=Farnesyltranstransferase 11; AltName: Full=Geranyltranstransferase 11; Flags: Precursor [Arabidopsis thaliana]