Gene/Proteome Database (LMPD)

LMPD ID
LMP010243
Gene ID
841833
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
GDSL-motif lipase 2
Gene Symbol
GLIP2
Synonyms
GDSL-motif lipase 2; GLIP2; T18A20.17
Alternate Names
GDSL-motif lipase 2
Chromosome
1
EC Number
3.1.1.-
Summary
Encodes a lipase, has in vitro lipase activity with p-nitrophenyl acetate and p-nitrophenyl butyrate, gene expression induced by hormones, negatively regulates auxin signaling, involved in disease resistance
Orthologs
View orthologs and multiple alignments for GLIP2

Proteins

GDSL-motif lipase 2
Refseq ID NP_175797
Protein GI 15220995
UniProt ID Q9SYF0
mRNA ID NM_104272
Length 436
RefSeq Status REVIEWED
MENSRSTLIIFFAYTTIILIGSINCRDNNNNNLVTNQSALFVFGDSVFDAGNNNYIDTLPSFRSNYWPYGQTTFKFPTGRVSDGRTIPDFIAEYAWLPLIPAYLQPSNGKNQFPYGVSFASAGAGALVGTFPGMVINLKSQLNNFKKVEKLLRSTLGEAQGKMVISRAVYLFHIGVNDYQYPFSTNSSIFQSSPQEIYVDFVVGNTTAVIKEVYKIGGRKFGFLNMGAYDCAPASLIIDQTKIGTCFKPVTELINLHNEKLESGLRRLERELSGFKYALHDYHTSLSVRMNNPSKYGFKEGKMACCGTGPLRGINTCGGRMGVSQSYELCEKVTDYLFFDHFHLTEKAHQQIAELIWSGPTNGLRKGIRHVCGTGPLRGINTCGGRVSAQVQGYELCENVADYLFLNSFHLIEKAHRQTTDRRDYLERTGQCYRTL

Gene Information

Entrez Gene ID
841833
Gene Name
GDSL-motif lipase 2
Gene Symbol
GLIP2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0016298 IDA:UniProtKB F lipase activity
GO:0009734 IEA:UniProtKB-KW P auxin-activated signaling pathway
GO:0009814 IMP:UniProtKB P defense response, incompatible interaction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0006629 IDA:UniProtKB P lipid metabolic process
GO:0010930 IMP:UniProtKB P negative regulation of auxin mediated signaling pathway
GO:0009723 IEP:UniProtKB P response to ethylene
GO:0009753 IEP:UniProtKB P response to jasmonic acid
GO:0009751 IEP:UniProtKB P response to salicylic acid

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-3301 sinapate ester biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001087 Lipase, GDSL
IPR008265 Lipase, GDSL, active site

UniProt Annotations

Entry Information

Gene Name
GDSL-motif lipase 2
Protein Entry
GLIP2_ARATH
UniProt ID
Q9SYF0
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype In glip2, enhanced auxin responses, and higher susceptibility to E.carotovora. {ECO:0000269|PubMed:19146828}.
Function Involved in the resistance to the necrotropic bacteria Erwinia carotovora, probably via negative regulation of auxin signaling. Possesses lipase and antimicrobial activities, inhibiting germination of fungal spores (e.g. Alternaria brassicicola). {ECO:0000269|PubMed:19146828}.
Induction In roots, by salicylic acid (SA), jasmonic acid (JA), and ethylene (ET) treatments. {ECO:0000269|PubMed:19146828}.
Sequence Caution Sequence=AEE33028.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the 'GDSL' lipolytic enzyme family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Expressed seedlings, roots and stems. {ECO:0000269|PubMed:19146828}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010243 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15220995 RefSeq NP_175797 436 GDSL-motif lipase 2

Identical Sequences to LMP010243 proteins

Reference Database Accession Length Protein Name
GI:15220995 EMBL CBC09178.1 436 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC10245.1 436 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC89555.1 436 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC58424.1 436 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC57280.1 436 unnamed protein product [Arabidopsis thaliana]
GI:15220995 GenBank AEE33028.1 436 GDSL-motif lipase 2 [Arabidopsis thaliana]

Related Sequences to LMP010243 proteins

Reference Database Accession Length Protein Name
GI:15220995 EMBL CBC26274.1 376 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC39801.1 376 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC09190.1 376 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC10523.1 376 unnamed protein product [Arabidopsis thaliana]
GI:15220995 EMBL CBC57306.1 376 unnamed protein product [Arabidopsis thaliana]
GI:15220995 SwissProt Q9SYF0.1 376 RecName: Full=GDSL esterase/lipase 2; AltName: Full=Extracellular lipase 2; Flags: Precursor [Arabidopsis thaliana]