Gene/Proteome Database (LMPD)

LMPD ID
LMP010134
Gene ID
829157
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
diacylglycerol kinase 7
Gene Symbol
DGK7
Synonyms
ATDGK7; DGK7; diacylglycerol kinase 7; F17I23.320; F17I23_320
Alternate Names
diacylglycerol kinase 7
Chromosome
4
EC Number
2.7.1.107
Summary
encodes a diacylglycerol kinase. Applying a specific diacylglycerol kinase inhibitor to the growth media resulted in reduced root elongation and plant growth. Gene is expressed throughout the plant but is strongest in flowers and young seedlings.
Orthologs
View orthologs and multiple alignments for DGK7

Proteins

diacylglycerol kinase 7
Refseq ID NP_567845
Protein GI 240256105
UniProt ID F4JQ95
mRNA ID NM_119180
Length 492
RefSeq Status REVIEWED
MEETPRSVGEASTTNFVAARPSAKTDDAVTMRGCGFANLALVGIDKEELRGRLAMPEYLRIAMRDCIKRKDSTEISDHLLLPGGAAADMAPHAPMVVFINPKSGGRHGPVLKERLQQLMTEEQVFDLTEVKPHEFVRYGLGCLDTLAAKGDECARECREKIRIMVAGGDGTVGWVLGCLGELHKDGKSHIPPVGVIPLGTGNDLSRSFSWGGSFPFAWRSAMKRTLHRATLGSIARLDSWKIVVSMPSGEVVDPPYSLKPTIEETALDQALDADGDVPPKAKSYEGVFYNYFSIGMDAQVAYGFHHLRNEKPYLAQGPVTNKIIYSSYSCTQGWFCTPCVNNPALRGLRNIMKIHIKKANCSEWEEIHVPKSVRSIVVLNLYNYGSGRHPWGNLRPKYLEKRGFVEAHCDDGLIEIFGLKQGWHASFVMAEIISAKHIAQAAAIRFELRGGDWKNAFLQMDGEPWKQPMKSDYSTFVEIKKVPFQSLMINGE

Gene Information

Entrez Gene ID
829157
Gene Name
diacylglycerol kinase 7
Gene Symbol
DGK7
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005886 IDA:TAIR C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0003951 IEA:InterPro F NAD+ kinase activity
GO:0004143 IDA:TAIR F diacylglycerol kinase activity
GO:0006952 IEA:UniProtKB-KW P defense response
GO:0048366 IMP:TAIR P leaf development
GO:0007205 IEA:InterPro P protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0048364 IMP:TAIR P root development

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath00564 Glycerophospholipid metabolism
ath01100 Metabolic pathways
ath04070 Phosphatidylinositol signaling system

Domain Information

InterPro Annotations

Accession Description
IPR016064 ATP-NAD kinase-like domain
IPR000756 Diacylglycerol kinase, accessory domain
IPR001206 Diacylglycerol kinase, catalytic domain
IPR016961 Diacylglycerol kinase, plant

UniProt Annotations

Entry Information

Gene Name
diacylglycerol kinase 7
Protein Entry
DGK7_ARATH
UniProt ID
F4JQ95
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: KM=0.74 mM for ATP {ECO:0000269|PubMed:16081412}; Vmax=0.34 pmol/min/ug enzyme toward 1,2-dioleoyl-sn-glycerol {ECO:0000269|PubMed:16081412}; pH dependence: Optimum pH is 6.8. {ECO:0000269|PubMed:16081412};
Catalytic Activity ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate. {ECO:0000269|PubMed:16081412}.
Function Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress xhibits high specificity for 1,2-dioleoyl-sn-glycerol (1,2-DOG), 1-palmitoyl, 2-oleoyl-sn- glycerol (1,2 POG), 1-stearoyl, 2-linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG). {ECO:0000269|PubMed:16081412, ECO:0000269|PubMed:23346092}.
Sequence Caution Sequence=AAK25884.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=AAM44963.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=AAU04880.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=CAB81027.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the eukaryotic diacylglycerol kinase family. {ECO:0000305}.
Similarity Contains 1 DAGKc domain. {ECO:0000255|PROSITE- ProRule:PRU00783}.
Subunit Monomer. {ECO:0000250}.
Tissue Specificity Highly expressed in flowers, and at low levels in roots, stems and leaves. {ECO:0000269|PubMed:16081412}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010134 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
240256105 RefSeq NP_567845 492 diacylglycerol kinase 7

Identical Sequences to LMP010134 proteins

Reference Database Accession Length Protein Name
GI:240256105 GenBank AEE85754.1 492 diacylglycerol kinase 7 [Arabidopsis thaliana]
GI:240256105 SwissProt F4JQ95.1 492 RecName: Full=Diacylglycerol kinase 7; Short=AtDGK7; Short=DAG kinase 7; AltName: Full=Diglyceride kinase 7; Short=DGK 7 [Arabidopsis thaliana]

Related Sequences to LMP010134 proteins

Reference Database Accession Length Protein Name
GI:240256105 EMBL CAB81027.1 490 putative protein [Arabidopsis thaliana]
GI:240256105 GenBank ABC71078.1 492 diacylglycerol kinase 7 [Arabidopsis thaliana]
GI:240256105 GenBank EFH43613.1 494 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:240256105 RefSeq XP_002867354.1 494 predicted protein [Arabidopsis lyrata subsp. lyrata]
GI:240256105 RefSeq XP_010438190.1 494 PREDICTED: diacylglycerol kinase 7-like [Camelina sativa]
GI:240256105 RefSeq XP_010447733.1 494 PREDICTED: diacylglycerol kinase 7 [Camelina sativa]