LIPID MAPS

Gene/Proteome Database (LMPD)

LMPD ID

LMP010132

Gene ID

816624

Species

Arabidopsis thaliana (Arabidopsis)

Gene Name

diacylglycerol kinase 5

Gene Symbol

DGK5

Synonyms

ATDGK5; DGK5; diacylglycerol kinase 5; F5H14.13; F5H14_13

Alternate Names

diacylglycerol kinase 5

Chromosome

EC Number

2.7.1.107

Proteins

diacylglycerol kinase 5
Refseq ID	NP_001031381
Protein GI	79322579
UniProt ID	Q9C5E5
mRNA ID	NM_001036304
Length	509
RefSeq Status	REVIEWED
MEKYNSLSDFLKEFYIPTYVLSAETEEEEEEESRPTPASPVLVFINSKSGGQLGGELILTYRSLLNHNQVFDLDQETPDKVLRRIYLNLERLKDDDFARQIREKLKIIVAGGDGTAGWLLGVVCDLKLSHPPPIATVPLGTGNNLPFAFGWGKKNPGTDRTAVESFLEQVLKAKVMKIDNWHILMRMKTPKEGGSCDPVAPLELPHSLHAFHRVSPTDELNKEGCHTFRGGFWNYFSLGMDAQISYAFHSERKLHPEKFKNQLVNQSTYVKLGCTQGWFCASLFHPASRNIAQLAKVKIATRNGQWQDLHIPHSIRSIVCLNLPSFSGGLNPWGTPNPRKQRDRGLTPPFVDDGLIEVVGFRNAWHGLVLLAPNGHGTRLAQANRIRFEFHKGATDHTFMRMDGEPWKQPLPLDDETVMVEISHLGQVNMLATHDCRSRSVFDPSTPRHQDGAEDYDDNEDDSVAEGEEFRKFGAADTFKIPDEGEHSNKKGRASRRRNSNVHGWSHVL

diacylglycerol kinase 5
Refseq ID	NP_850007
Protein GI	30681194
UniProt ID	Q9C5E5
mRNA ID	NM_179676
Length	509
RefSeq Status	REVIEWED
MEKYNSLSDFLKEFYIPTYVLSAETEEEEEEESRPTPASPVLVFINSKSGGQLGGELILTYRSLLNHNQVFDLDQETPDKVLRRIYLNLERLKDDDFARQIREKLKIIVAGGDGTAGWLLGVVCDLKLSHPPPIATVPLGTGNNLPFAFGWGKKNPGTDRTAVESFLEQVLKAKVMKIDNWHILMRMKTPKEGGSCDPVAPLELPHSLHAFHRVSPTDELNKEGCHTFRGGFWNYFSLGMDAQISYAFHSERKLHPEKFKNQLVNQSTYVKLGCTQGWFCASLFHPASRNIAQLAKVKIATRNGQWQDLHIPHSIRSIVCLNLPSFSGGLNPWGTPNPRKQRDRGLTPPFVDDGLIEVVGFRNAWHGLVLLAPNGHGTRLAQANRIRFEFHKGATDHTFMRMDGEPWKQPLPLDDETVMVEISHLGQVNMLATHDCRSRSVFDPSTPRHQDGAEDYDDNEDDSVAEGEEFRKFGAADTFKIPDEGEHSNKKGRASRRRNSNVHGWSHVL

diacylglycerol kinase 5
Refseq ID	NP_565492
Protein GI	18399515
UniProt ID	Q9C5E5
mRNA ID	NM_127660
Length	491
RefSeq Status	REVIEWED
MEKYNSLSDFLKEFYIPTYVLSAETEEEEEEESRPTPASPVLVFINSKSGGQLGGELILTYRSLLNHNQVFDLDQETPDKVLRRIYLNLERLKDDDFARQIREKLKIIVAGGDGTAGWLLGVVCDLKLSHPPPIATVPLGTGNNLPFAFGWGKKNPGTDRTAVESFLEQVLKAKVMKIDNWHILMRMKTPKEGGSCDPVAPLELPHSLHAFHRVSPTDELNKEGCHTFRGGFWNYFSLGMDAQISYAFHSERKLHPEKFKNQLVNQSTYVKLGCTQGWFCASLFHPASRNIAQLAKVKIATRNGQWQDLHIPHSIRSIVCLNLPSFSGGLNPWGTPNPRKQRDRGLTPPFVDDGLIEVVGFRNAWHGLVLLAPNGHGTRLAQANRIRFEFHKGATDHTFMRMDGEPWKQPLPLDDETVMVEISHLGQVNMLATHDCRSRSVFDPSTPRHQDGAEDYDDNEDDSVAEGEEFRKFGAADTFKIPDEVDISQLS

diacylglycerol kinase 5
Refseq ID	NP_973498
Protein GI	42570849
UniProt ID	Q9C5E5
mRNA ID	NM_201769
Length	491
RefSeq Status	REVIEWED
MEKYNSLSDFLKEFYIPTYVLSAETEEEEEEESRPTPASPVLVFINSKSGGQLGGELILTYRSLLNHNQVFDLDQETPDKVLRRIYLNLERLKDDDFARQIREKLKIIVAGGDGTAGWLLGVVCDLKLSHPPPIATVPLGTGNNLPFAFGWGKKNPGTDRTAVESFLEQVLKAKVMKIDNWHILMRMKTPKEGGSCDPVAPLELPHSLHAFHRVSPTDELNKEGCHTFRGGFWNYFSLGMDAQISYAFHSERKLHPEKFKNQLVNQSTYVKLGCTQGWFCASLFHPASRNIAQLAKVKIATRNGQWQDLHIPHSIRSIVCLNLPSFSGGLNPWGTPNPRKQRDRGLTPPFVDDGLIEVVGFRNAWHGLVLLAPNGHGTRLAQANRIRFEFHKGATDHTFMRMDGEPWKQPLPLDDETVMVEISHLGQVNMLATHDCRSRSVFDPSTPRHQDGAEDYDDNEDDSVAEGEEFRKFGAADTFKIPDEVDISQLS

Gene Information

Entrez Gene ID

816624

Gene Name

diacylglycerol kinase 5

Gene Symbol

DGK5

Species

Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0003951	IEA:InterPro	F	NAD+ kinase activity
GO:0004143	IEA:UniProtKB-EC	F	diacylglycerol kinase activity
GO:0006952	IEA:UniProtKB-KW	P	defense response
GO:0007205	IEA:InterPro	P	protein kinase C-activating G-protein coupled receptor signaling pathway

KEGG Pathway Links

KEGG Pathway ID	Description
ath00561	Glycerolipid metabolism
ath00564	Glycerophospholipid metabolism
ath01100	Metabolic pathways
ath04070	Phosphatidylinositol signaling system

Domain Information

InterPro Annotations

Accession	Description
IPR016064	ATP-NAD kinase-like domain
IPR000756	Diacylglycerol kinase, accessory domain
IPR001206	Diacylglycerol kinase, catalytic domain
IPR016961	Diacylglycerol kinase, plant

UniProt Annotations

Entry Information

Gene Name

diacylglycerol kinase 5

Protein Entry

DGK5_ARATH

UniProt ID

Q9C5E5

Species

Arabidopsis

Comments

Comment Type	Description
Alternative Products	Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9C5E5-1; Sequence=Displayed; Name=2; IsoId=Q9C5E5-2; Sequence=VSP_046410, VSP_046411; Note=No experimental confirmation available.;
Catalytic Activity	ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate.
Function	Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity). {ECO:0000250}.
Similarity	Belongs to the eukaryotic diacylglycerol kinase family. {ECO:0000305}.
Similarity	Contains 1 DAGKc domain. {ECO:0000255\|PROSITE- ProRule:PRU00783}.
Subunit	Monomer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010132 (as displayed in Record Overview)

Protein GI	Database	Accession	Length	Protein Name
79322579	RefSeq	NP_001031381	509	diacylglycerol kinase 5
30681194	RefSeq	NP_850007	509	diacylglycerol kinase 5
18399515	RefSeq	NP_565492	491	diacylglycerol kinase 5
42570849	RefSeq	NP_973498	491	diacylglycerol kinase 5

Identical Sequences to LMP010132 proteins

Reference	Database	Accession	Length	Protein Name
GI:42570849	DBBJ	BAH19585.1	491	AT2G20900 [Arabidopsis thaliana]
GI:18399515	DBBJ	BAH19585.1	491	AT2G20900 [Arabidopsis thaliana]
GI:42570849	DBBJ	BAH20135.1	491	AT2G20900 [Arabidopsis thaliana]
GI:18399515	DBBJ	BAH20135.1	491	AT2G20900 [Arabidopsis thaliana]
GI:30681194	GenBank	AAK26010.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:79322579	GenBank	AAK26010.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:30681194	GenBank	AAN41383.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:79322579	GenBank	AAN41383.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:30681194	GenBank	AEC07093.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	GenBank	AEC07093.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:42570849	GenBank	AEC07094.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	GenBank	AEC07094.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:42570849	GenBank	AEC07095.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	GenBank	AEC07095.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	GenBank	AEC07096.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	GenBank	AEC07096.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	gnl	TIGR	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:42570849	gnl	TIGR	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:42570849	RefSeq	NP_565492.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	RefSeq	NP_850007.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	RefSeq	NP_973498.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	RefSeq	NP_001031381.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	SwissProt	Q9C5E5.1	509	RecName: Full=Diacylglycerol kinase 5; Short=AtDGK5; Short=DAG kinase 5; AltName: Full=Diglyceride kinase 5; Short=DGK 5 [Arabidopsis thaliana]
GI:30681194	SwissProt	Q9C5E5.1	509	RecName: Full=Diacylglycerol kinase 5; Short=AtDGK5; Short=DAG kinase 5; AltName: Full=Diglyceride kinase 5; Short=DGK 5 [Arabidopsis thaliana]

Related Sequences to LMP010132 proteins

Reference	Database	Accession	Length	Protein Name
GI:79322579	DBBJ	BAH20135.1	491	AT2G20900 [Arabidopsis thaliana]
GI:30681194	DBBJ	BAH20135.1	491	AT2G20900 [Arabidopsis thaliana]
GI:42570849	GenBank	AAK26010.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:18399515	GenBank	AAK26010.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:18399515	GenBank	AAM62810.1	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:42570849	GenBank	AAM62810.1	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:18399515	GenBank	AAN41383.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:42570849	GenBank	AAN41383.1	509	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:18399515	GenBank	AEC07093.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:42570849	GenBank	AEC07093.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	GenBank	AEC07094.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	GenBank	AEC07094.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	GenBank	AEC07095.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	GenBank	AEC07095.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	GenBank	AEC07096.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:42570849	GenBank	AEC07096.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	gnl	TIGR	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:79322579	gnl	TIGR	491	putative diacylglycerol kinase [Arabidopsis thaliana]
GI:30681194	RefSeq	NP_565492.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	RefSeq	NP_565492.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:42570849	RefSeq	NP_850007.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:18399515	RefSeq	NP_850007.1	509	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:79322579	RefSeq	NP_973498.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]
GI:30681194	RefSeq	NP_973498.1	491	diacylglycerol kinase 5 [Arabidopsis thaliana]