Gene/Proteome Database (LMPD)

LMPD ID
LMP009778
Gene ID
819707
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
acyl-CoA binding protein 4
Gene Symbol
ACBP4
Synonyms
acyl-CoA binding protein 4; F22F7.13; F22F7_13
Alternate Names
acyl-CoA binding protein 4
Chromosome
3
Summary
Acyl-CoA binding protein with high affinity for oleoyl-CoA. Expressed in all plant organs. Involved in fatty acid transport.
Orthologs
View orthologs and multiple alignments for ACBP4

Proteins

acyl-CoA binding protein 4
Refseq ID NP_974227
Protein GI 42572263
UniProt ID Q9MA55
mRNA ID NM_202498
Length 669
RefSeq Status REVIEWED
MAMPRATSGPAYPERFYAAASYVGLDGSDSSAKNVISKFPDDTALLLYALYQQATVGPCNTPKPSAWRPVEQSKWKSWQGLGTMPSIEAMRLFVKILEEDDPGWYSRASNDIPDPVVDVQINQRAKDEPVVENGSTFSETKTISTENGRLAETQDKDVVSEDSNTVSVYNQWTAPQTSGQRPKARYEHGAAVIQDKMYIYGGNHNGRYLGDLHVLDLKSWTWSRVETKVATESQETSTPTLLAPCAGHSLIAWDNKLLSIGGHTKDPSESMQVKVFDPHTITWSMLKTYGKPPVSRGGQSVTMVGKTLVIFGGQDAKRSLLNDLHILDLDTMTWDEIDAVGVSPSPRSDHAAAVHAERFLLIFGGGSHATCFDDLHVLDLQTMEWSRPAQQGDAPTPRAGHAGVTIGENWFIVGGGDNKSGASESVVLNMSTLAWSVVASVQGRVPLASEGLSLVVSSYNGEDVLVAFGGYNGRYNNEINLLKPSHKSTLQTKTLEAPLPGSLSAVNNATTRDIESEVEVSQEGRVREIVMDNVNPGSKVEGNSERIIATIKSEKEELEASLNKERMQTLQLRQELGEAELRNTDLYKELQSVRGQLAAEQSRCFKLEVDVAELRQKLQTLETLQKELELLQRQKAASEQAAMNAKRQGSGGVWGWLAGSPQEKDDDSP
acyl-CoA binding protein 4
Refseq ID NP_187193
Protein GI 42563520
UniProt ID Q9MA55
mRNA ID NM_111415
Length 668
RefSeq Status REVIEWED
MAMPRATSGPAYPERFYAAASYVGLDGSDSSAKNVISKFPDDTALLLYALYQQATVGPCNTPKPSAWRPVEQSKWKSWQGLGTMPSIEAMRLFVKILEEDDPGWYSRASNDIPDPVVDVQINRAKDEPVVENGSTFSETKTISTENGRLAETQDKDVVSEDSNTVSVYNQWTAPQTSGQRPKARYEHGAAVIQDKMYIYGGNHNGRYLGDLHVLDLKSWTWSRVETKVATESQETSTPTLLAPCAGHSLIAWDNKLLSIGGHTKDPSESMQVKVFDPHTITWSMLKTYGKPPVSRGGQSVTMVGKTLVIFGGQDAKRSLLNDLHILDLDTMTWDEIDAVGVSPSPRSDHAAAVHAERFLLIFGGGSHATCFDDLHVLDLQTMEWSRPAQQGDAPTPRAGHAGVTIGENWFIVGGGDNKSGASESVVLNMSTLAWSVVASVQGRVPLASEGLSLVVSSYNGEDVLVAFGGYNGRYNNEINLLKPSHKSTLQTKTLEAPLPGSLSAVNNATTRDIESEVEVSQEGRVREIVMDNVNPGSKVEGNSERIIATIKSEKEELEASLNKERMQTLQLRQELGEAELRNTDLYKELQSVRGQLAAEQSRCFKLEVDVAELRQKLQTLETLQKELELLQRQKAASEQAAMNAKRQGSGGVWGWLAGSPQEKDDDSP

Gene Information

Entrez Gene ID
819707
Gene Name
acyl-CoA binding protein 4
Gene Symbol
ACBP4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:UniProtKB C cytoplasm
GO:0005829 IDA:TAIR C cytosol
GO:0005634 IDA:TAIR C nucleus
GO:0000062 IDA:TAIR F fatty-acyl-CoA binding
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0006869 IDA:TAIR P lipid transport
GO:0009723 IEP:UniProtKB P response to ethylene
GO:0009753 IEP:UniProtKB P response to jasmonic acid
GO:0009416 TAS:UniProtKB P response to light stimulus
GO:0006810 IEA:UniProtKB-KW P transport

Domain Information

InterPro Annotations

Accession Description
IPR000582 Acyl-CoA-binding protein, ACBP
IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle
IPR011498 Kelch repeat type 2
IPR015915 Kelch-type beta propeller

UniProt Annotations

Entry Information

Gene Name
acyl-CoA binding protein 4
Protein Entry
ACBP4_ARATH
UniProt ID
Q9MA55
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9MA55-1; Sequence=Displayed; Name=2; IsoId=Q9MA55-2; Sequence=VSP_037739; Note=Derived from EST data. No experimental confirmation available.;
Function Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with oleoyl-CoA, barely with palmitoyl-CoA, but not with arachidonyl-CoA. May function as an intracellular carrier of acyl-CoA esters. Plays a role in the biosynthesis of membrane lipids including galactolipids and phospholipids. {ECO:0000269|PubMed:15604682, ECO:0000269|PubMed:18773301}.
Induction By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Up- regulated in the light and down-regulated in constant darkness. {ECO:0000269|PubMed:18836139}.
Interaction P42736:RAP2-3; NbExp=4; IntAct=EBI-2009699, EBI-368243;
Similarity Belongs to the ACBP family. {ECO:0000305}.
Similarity Contains 1 ACB (acyl-CoA-binding) domain. {ECO:0000255|PROSITE-ProRule:PRU00573}.
Similarity Contains 6 Kelch repeats. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18773301, ECO:0000269|PubMed:18836139}. Note=Also to the periphery of the nucleus.
Subunit Interacts with RAP2-3/EBP, an ethylene-responsive element binding protein. {ECO:0000269|PubMed:18836139}.
Tissue Specificity Mostly expressed in roots, stems, and leaves, and, to a lower extent, in flowers and siliques. {ECO:0000269|PubMed:15604682, ECO:0000269|PubMed:18836139}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009778 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
42572263 RefSeq NP_974227 669 acyl-CoA binding protein 4
42563520 RefSeq NP_187193 668 acyl-CoA binding protein 4

Identical Sequences to LMP009778 proteins

Reference Database Accession Length Protein Name
GI:42563520 DBBJ BAF00008.1 668 hypothetical protein [Arabidopsis thaliana]
GI:42563520 GenBank AAF64540.1 668 unknown protein [Arabidopsis thaliana]
GI:42563520 GenBank AAP21266.1 668 At3g05420 [Arabidopsis thaliana]
GI:42563520 GenBank AED37547.1 668 Sequence 30 from patent US 7880053
GI:42563520 GenBank AEE74237.1 668 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42572263 GenBank AEE74238.1 669 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42563520 SwissProt Q9MA55.1 668 RecName: Full=Acyl-CoA-binding domain-containing protein 4; Short=Acyl-CoA binding protein 4 [Arabidopsis thaliana]

Related Sequences to LMP009778 proteins

Reference Database Accession Length Protein Name
GI:42572263 DBBJ BAF00008.1 668 hypothetical protein [Arabidopsis thaliana]
GI:42572263 GenBank AAF64540.1 668 unknown protein [Arabidopsis thaliana]
GI:42563520 GenBank EFH58671.1 669 acyl-CoA binding protein 4, acyl-CoA-binding domain 4 [Arabidopsis lyrata subsp. lyrata]
GI:42572263 GenBank AED37547.1 668 Sequence 30 from patent US 7880053
GI:42572263 GenBank AEE74237.1 668 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42563520 GenBank AEE74238.1 669 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42572263 RefSeq NP_187193.3 668 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42563520 RefSeq NP_974227.1 669 acyl-CoA binding protein 4 [Arabidopsis thaliana]
GI:42563520 RefSeq XP_002882412.1 669 acyl-CoA binding protein 4, acyl-CoA-binding domain 4 [Arabidopsis lyrata subsp. lyrata]
GI:42563520 RefSeq XP_010464068.1 668 PREDICTED: acyl-CoA-binding domain-containing protein 4-like isoform X2 [Camelina sativa]
GI:42563520 RefSeq XP_010485986.1 668 PREDICTED: acyl-CoA-binding domain-containing protein 4 isoform X2 [Camelina sativa]
GI:42572263 SwissProt Q9MA55.1 668 RecName: Full=Acyl-CoA-binding domain-containing protein 4; Short=Acyl-CoA binding protein 4 [Arabidopsis thaliana]