Gene/Proteome Database (LMPD)

LMPD ID
LMP009707
Gene ID
843456
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
3-ketoacyl-CoA synthase 7
Gene Symbol
KCS7
Synonyms
3-ketoacyl-CoA synthase 7; F23N20.15; F23N20_15; KCS7
Alternate Names
3-ketoacyl-CoA synthase 7
Chromosome
1
EC Number
2.3.1.199
Summary
Encodes KCS7, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
Orthologs
View orthologs and multiple alignments for KCS7

Proteins

3-ketoacyl-CoA synthase 7
Refseq ID NP_177272
Protein GI 15223964
UniProt ID Q9C992
mRNA ID NM_105785
Length 460
RefSeq Status REVIEWED
MESSFHFINEALLITQTFITFHQFLVASACVLIAVFGYYFFKPRCIIYLIDFSCYQPPDFLRAPVSNFIEHLTISGVFDQESLDLQQKILERSGISDDASVPATVHEIPPNASISAAREETHEILFAIVQDLFSKHEIDPKSIDILVSNCSLFCPSPSITSMIINKFGMRSDIKSFSLSGMGCSAGILSVNLVKDLMKIHGDSLALVLSMEAVSPNGYRGKCKSMLIANTIFRMGGAAILLSNRKQDSHKAKYKLQHIIRTHVGSDTESYESVMQQVDEEGKVGVALSKQLVRVASKALKINVVQLGPRVLPYSEQLKYIISFIQRKWGMHKEIYTPNFKKAFEHFCIHAGGRAIIEGVEKHLKLDKEDVEASRSTLYRYGNTSSSSLWYELQYLEAKGRMKMGDKVWQIGFGSGFKANSAVWKCISEIDSRGRNAWSDRIHLYPVCGDTSSALKTELLS

Gene Information

Entrez Gene ID
843456
Gene Name
3-ketoacyl-CoA synthase 7
Gene Symbol
KCS7
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016747 IEA:InterPro F transferase activity, transferring acyl groups other than amino-acyl groups
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum
ath00062 Fatty acid elongation

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5080 very long chain fatty acid biosynthesis I

Domain Information

InterPro Annotations

Accession Description
IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal
IPR013601 FAE1/Type III polyketide synthase-like protein
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup
IPR012392 Very-long-chain 3-ketoacyl-CoA synthase

UniProt Annotations

Entry Information

Gene Name
3-ketoacyl-CoA synthase 7
Protein Entry
KCS7_ARATH
UniProt ID
Q9C992
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Induction Repressed by herbicides such as flufenacet and benfuresate. {ECO:0000269|PubMed:12916765}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Similarity Belongs to the chalcone/stilbene synthases family. {ECO:0000305}.
Similarity Contains 1 FAE (fatty acid elongase) domain. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009707 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15223964 RefSeq NP_177272 460 3-ketoacyl-CoA synthase 7

Identical Sequences to LMP009707 proteins

Reference Database Accession Length Protein Name
GI:15223964 EMBL CAW45918.1 460 unnamed protein product [Arabidopsis thaliana]
GI:15223964 EMBL CAW71178.1 460 unnamed protein product [Arabidopsis thaliana]
GI:15223964 EMBL CBC11420.1 460 unnamed protein product [Arabidopsis thaliana]
GI:15223964 EMBL CBC60862.1 460 unnamed protein product [Arabidopsis thaliana]
GI:15223964 GenBank AEE35167.1 460 3-ketoacyl-CoA synthase 7 [Arabidopsis thaliana]
GI:15223964 SwissProt Q9C992.1 460 RecName: Full=3-ketoacyl-CoA synthase 7; Short=KCS-7; AltName: Full=Very long-chain fatty acid condensing enzyme 7; Short=VLCFA condensing enzyme 7 [Arabidopsis thaliana]

Related Sequences to LMP009707 proteins

Reference Database Accession Length Protein Name
GI:15223964 GenBank EFH65082.1 460 beta-ketoacyl-CoA synthase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15223964 GenBank EOA33322.1 460 hypothetical protein CARUB_v10021968mg [Capsella rubella]
GI:15223964 RefSeq XP_002888823.1 460 beta-ketoacyl-CoA synthase family protein [Arabidopsis lyrata subsp. lyrata]
GI:15223964 RefSeq XP_006300424.1 460 hypothetical protein CARUB_v10021968mg [Capsella rubella]
GI:15223964 RefSeq XP_010427942.1 461 PREDICTED: 3-ketoacyl-CoA synthase 7 [Camelina sativa]
GI:15223964 RefSeq XP_010471128.1 508 PREDICTED: 3-ketoacyl-CoA synthase 7-like isoform X1 [Camelina sativa]