Gene/Proteome Database (LMPD)

LMPD ID
LMP009162
Gene ID
37246
Species
Drosophila melanogaster (Drosophila)
Gene Name
Rab escort protein
Gene Symbol
Rep
Synonyms
CG8432; Dmel\CG8432; REP
Chromosome
2R
Map Location
56D13-56D13

Proteins

Rab escort protein
Refseq ID NP_477420
Protein GI 17137652
UniProt ID Q9V8W3
mRNA ID NM_058072
Length 511
RefSeq Status REVIEWED
MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDALCARLDQEVEPHSALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEFRAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFLTACNDYGEDKCNEDSLEFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFEEGMQRTQRFLGSLGRYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFLLSSAGKTLRAKNVVSAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLLDNEGGREAFLIQLSHYTGACPEGLYIFHLTTPALSEDPASDLAIFTSQLFDQSDAQIIFSSYFTIAAQSSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRAPDPEEIVVDGEDPSALNEHTLPEDLRAQLHDMQQATQEMDIQE

Gene Information

Entrez Gene ID
37246
Gene Name
Rab escort protein
Gene Symbol
Rep
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005818 IDA:UniProtKB C aster
GO:0005737 ISS:UniProtKB C cytoplasm
GO:0016020 ISS:UniProtKB C membrane
GO:0048471 IDA:UniProtKB C perinuclear region of cytoplasm
GO:0000922 IDA:UniProtKB C spindle pole
GO:0008021 NAS:FlyBase C synaptic vesicle
GO:0005096 IEA:UniProtKB-KW F GTPase activator activity
GO:0007049 IEA:UniProtKB-KW P cell cycle
GO:0007269 NAS:FlyBase P neurotransmitter secretion
GO:0018344 IDA:FlyBase P protein geranylgeranylation
GO:0016192 NAS:FlyBase P vesicle-mediated transport

Domain Information

InterPro Annotations

Accession Description
IPR018203 GDP_dissociation_inhibitor
IPR016664 Rab protein geranylgeranyltransferase component A, eukaryota

UniProt Annotations

Entry Information

Gene Name
Rab escort protein
Protein Entry
Q9V8W3_DROME
UniProt ID
Q9V8W3
Species
Drosophila

Comments

Comment Type Description
Developmental Stage Expressed in the syncytial embryo.
Function Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity).
Similarity Belongs to the Rab GDI family.
Subcellular Location Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, spindle pole . Note=Coordinated with the cell cycle, located around nuclei during prophase and telophase. Located to spindle poles during metaphase.

Identical and Related Proteins

Unique RefSeq proteins for LMP009162 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17137652 RefSeq NP_477420 511 Rab escort protein

Identical Sequences to LMP009162 proteins

Reference Database Accession Length Protein Name
GI:17137652 GenBank AAL28600.1 511 LD02194p [Drosophila melanogaster]
GI:17137652 GenBank ACL83974.1 511 Rep-PA, partial [synthetic construct]
GI:17137652 GenBank ACL89067.1 511 Rep-PA [synthetic construct]
GI:17137652 gnl FlyBase 511 Rab escort protein [Drosophila melanogaster]
GI:17137652 SwissProt Q9V8W3.1 511 RecName: Full=Rab proteins geranylgeranyltransferase component A; AltName: Full=Rab escort protein homolog; Short=REP [Drosophila melanogaster]

Related Sequences to LMP009162 proteins

Reference Database Accession Length Protein Name
GI:17137652 GenBank AAD16891.1 511 Rab escort protein homolog [Drosophila melanogaster]
GI:17137652 GenBank EDW48614.1 513 GM21968 [Drosophila sechellia]
GI:17137652 GenBank EDW91484.1 511 GE12059 [Drosophila yakuba]
GI:17137652 GenBank EDX07824.1 511 GD11461 [Drosophila simulans]
GI:17137652 RefSeq XP_002034601.1 513 GM21968 [Drosophila sechellia]
GI:17137652 RefSeq XP_002082239.1 511 GD11461 [Drosophila simulans]