Gene/Proteome Database (LMPD)

LMPD ID
LMP009159
Gene ID
31406
Species
Drosophila melanogaster (Drosophila)
Gene Name
lethal (1) G0334
Gene Symbol
l(1)G0334
Synonyms
CG 7010; CG7010; Dmel\CG7010; l (1) G0334; L(1)g0334
Chromosome
X
Map Location
4C14-4C14

Proteins

lethal (1) G0334, isoform A
Refseq ID NP_572181
Protein GI 28571106
UniProt ID Q9W4H6
mRNA ID NM_131953
Length 399
RefSeq Status REVIEWED
MLRTLSRVSELPIIVKQLQKNAAQAGVSKTNNYATEATVQVNRPFKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKLRGTIAYDIDHIQERKGVNH
lethal (1) G0334, isoform B
Refseq ID NP_726947
Protein GI 24639746
UniProt ID Q7YU05
mRNA ID NM_167019
Length 328
RefSeq Status REVIEWED
MQTIRRLETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKLRGTIAYDIDHIQERKGVNH
lethal (1) G0334, isoform C
Refseq ID NP_726945
Protein GI 24639740
UniProt ID Q7KVX1
mRNA ID NM_167017
Length 443
RefSeq Status REVIEWED
MLRTLSRVSELPIIVKQLQKRCHNNNNNNIIISGCRILSNNNNNSSIDIIRNGRYSSSFFGLFQNAAQAGVSKTNNYATEATVQVNRPFKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKLRGTIAYDIDHIQERKGVNH
lethal (1) G0334, isoform D
Refseq ID NP_726946
Protein GI 24639744
UniProt ID Q9W4H6
mRNA ID NM_167018
Length 399
RefSeq Status REVIEWED
Protein sequence is identical to GI:28571106 (mRNA isoform)

Gene Information

Entrez Gene ID
31406
Gene Name
lethal (1) G0334
Gene Symbol
l(1)G0334
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:FlyBase C mitochondrion
GO:0004739 IEA:UniProtKB-EC F pyruvate dehydrogenase (acetyl-transferring) activity
GO:0006096 IEA:InterPro P glycolytic process

Domain Information

InterPro Annotations

Accession Description
IPR001017 Dehydrogenase, E1 component
IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
IPR029061 Thiamin diphosphate-binding fold

UniProt Annotations

Entry Information

Gene Name
lethal (1) G0334
Protein Entry
Q9W4H6_DROME
UniProt ID
Q9W4H6
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2).
Cofactor Note=Thiamine pyrophosphate. ;
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

Identical and Related Proteins

Unique RefSeq proteins for LMP009159 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
28571106 RefSeq NP_572181 399 lethal (1) G0334, isoform A
24639746 RefSeq NP_726947 328 lethal (1) G0334, isoform B
24639740 RefSeq NP_726945 443 lethal (1) G0334, isoform C

Identical Sequences to LMP009159 proteins

Reference Database Accession Length Protein Name
GI:24639746 GenBank AAQ22537.1 328 LD13846p [Drosophila melanogaster]
GI:28571106 GenBank ADU79248.1 399 GM13002p [Drosophila melanogaster]
GI:24639740 GenBank ADX35969.1 443 RH59152p [Drosophila melanogaster]
GI:28571106 gnl FlyBase 399 lethal (1) G0334, isoform A [Drosophila melanogaster]
GI:24639740 gnl FlyBase 443 lethal (1) G0334, isoform C [Drosophila melanogaster]
GI:24639746 gnl FlyBase 328 lethal (1) G0334, isoform B [Drosophila melanogaster]
GI:28571106 gnl FlyBase 399 lethal (1) G0334, isoform D [Drosophila melanogaster]
GI:28571106 RefSeq NP_726946.1 399 lethal (1) G0334, isoform D [Drosophila melanogaster]

Related Sequences to LMP009159 proteins

Reference Database Accession Length Protein Name
GI:28571106 GenBank EDV45836.1 440 GG18722 [Drosophila erecta]
GI:24639740 GenBank EDV45836.1 440 GG18722 [Drosophila erecta]
GI:28571106 GenBank EDW53141.1 441 GM12361 [Drosophila sechellia]
GI:24639740 GenBank EDW53141.1 441 GM12361 [Drosophila sechellia]
GI:28571106 GenBank EDX01180.1 438 GE16361 [Drosophila yakuba]
GI:24639740 GenBank EDX01180.1 438 GE16361 [Drosophila yakuba]
GI:24639746 GenBank ADU79248.1 399 GM13002p [Drosophila melanogaster]
GI:24639746 gnl FlyBase 399 lethal (1) G0334, isoform A [Drosophila melanogaster]
GI:24639746 gnl FlyBase 443 lethal (1) G0334, isoform C [Drosophila melanogaster]
GI:24639746 gnl FlyBase 399 lethal (1) G0334, isoform D [Drosophila melanogaster]
GI:24639746 RefSeq NP_726946.1 399 lethal (1) G0334, isoform D [Drosophila melanogaster]
GI:24639746 RefSeq NP_572181.4 399 lethal (1) G0334, isoform A [Drosophila melanogaster]
GI:28571106 RefSeq XP_001976909.1 440 GG18722 [Drosophila erecta]
GI:24639740 RefSeq XP_001976909.1 440 GG18722 [Drosophila erecta]
GI:28571106 RefSeq XP_002036982.1 441 GM12361 [Drosophila sechellia]
GI:24639740 RefSeq XP_002036982.1 441 GM12361 [Drosophila sechellia]
GI:28571106 RefSeq XP_002100072.1 438 GE16361 [Drosophila yakuba]
GI:24639740 RefSeq XP_002100072.1 438 GE16361 [Drosophila yakuba]