Gene/Proteome Database (LMPD)

LMPD ID
LMP009153
Gene ID
31163
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG4406 gene product from transcript CG4406-RA
Gene Symbol
CG4406
Synonyms
cg4406; Dmel\CG4406; EG:133E12.3
Chromosome
X
Map Location
2C1-2C1

Proteins

CG4406
Refseq ID NP_569968
Protein GI 24639234
UniProt ID Q8T4E1
mRNA ID NM_130612
Length 355
RefSeq Status REVIEWED
MFNIMLVKFVVIFALILASCRVEADNTSVLPEGFVDAAQRSTHTNNWAVLVDASRFWFNYRHVANVLSIYRSVKRLGIPDSQIILMIADDMACNARNPRPGQVYNNANQHINVYGDDVEVDYRGYEVTVENFVRLLTGRTQNGTARSKKLLSDAGSNVLIYLTGHGGDGFLKFQDSEEITSQELADGIQQMWEKKRYNELFFMVDTCQAASLYEKFTSPNVLAVASSLVGEDSLSHHVDPSIGVYMIDRYTYYALEFLEKVQPFSKRTIGEFLQVCPKRVCISTVGVRKDLYPRDPHKVPITDFFGAIRPTRVSTDRINVTLANEDDFIFDKDKMVTKKPFKIVMESQFPSELFK

Gene Information

Entrez Gene ID
31163
Gene Name
CG4406 gene product from transcript CG4406-RA
Gene Symbol
CG4406
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042765 ISS:UniProtKB C GPI-anchor transamidase complex
GO:0003923 ISS:UniProtKB F GPI-anchor transamidase activity
GO:0004197 IEA:InterPro F cysteine-type endopeptidase activity
GO:0016255 IEA:InterPro P attachment of GPI anchor to protein

Domain Information

InterPro Annotations

Accession Description
IPR028361 GPI-anchor transamidase
IPR001096 Peptidase C13, legumain

UniProt Annotations

Entry Information

Gene Name
CG4406 gene product from transcript CG4406-RA
Protein Entry
Q8T4E1_DROME
UniProt ID
Q8T4E1
Species
Drosophila

Comments

Comment Type Description
Function Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity).
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Sequence Caution Sequence=CAA15687.1; Type=Erroneous gene model prediction; Evidence= ;
Similarity Belongs to the peptidase C13 family.

Identical and Related Proteins

Unique RefSeq proteins for LMP009153 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24639234 RefSeq NP_569968 355 CG4406

Identical Sequences to LMP009153 proteins

Reference Database Accession Length Protein Name
GI:24639234 GenBank AAL89972.1 355 AT02512p [Drosophila melanogaster]
GI:24639234 GenBank ACL87299.1 355 CG4406-PA, partial [synthetic construct]
GI:24639234 gnl FlyBase 355 CG4406 [Drosophila melanogaster]
GI:24639234 SwissProt Q8T4E1.1 355 RecName: Full=Putative GPI-anchor transamidase; Short=GPI transamidase; Flags: Precursor [Drosophila melanogaster]

Related Sequences to LMP009153 proteins

Reference Database Accession Length Protein Name
GI:24639234 GenBank EDV45549.1 351 GG12662 [Drosophila erecta]
GI:24639234 GenBank EDW43906.1 355 GM18930 [Drosophila sechellia]
GI:24639234 GenBank EDX01437.1 351 GE16991 [Drosophila yakuba]
GI:24639234 RefSeq XP_001982580.1 351 GG12662 [Drosophila erecta]
GI:24639234 RefSeq XP_002040435.1 355 GM18930 [Drosophila sechellia]
GI:24639234 RefSeq XP_002100329.1 351 GE16991 [Drosophila yakuba]