Gene/Proteome Database (LMPD)

LMPD ID
LMP009123
Gene ID
30995
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG17896 gene product from transcript CG17896-RB
Gene Symbol
CG17896
Synonyms
153323_at; Dmel\CG17896; EG:171D11.1
Chromosome
X
Map Location
1B5-1B5

Proteins

CG17896, isoform A
Refseq ID NP_726672
Protein GI 24638878
UniProt ID Q7KW39
mRNA ID NM_166844
Length 511
RefSeq Status REVIEWED
MARHLAKRSYSSAAPTTKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVTQLWRKTDVTHTQAAVAMPTMK
CG17896, isoform B
Refseq ID NP_569845
Protein GI 24638876
UniProt ID Q7KW39
mRNA ID NM_130489
Length 520
RefSeq Status REVIEWED
MSLVRLIGAEARHLAKRSYSSAAPTTKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTVTQLWRKTDVTHTQAAVAMPTMK

Gene Information

Entrez Gene ID
30995
Gene Name
CG17896 gene product from transcript CG17896-RB
Gene Symbol
CG17896
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0000062 ISS:UniProtKB F fatty-acyl-CoA binding
GO:0018478 ISS:UniProtKB F malonate-semialdehyde dehydrogenase (acetylating) activity
GO:0004491 ISS:UniProtKB F methylmalonate-semialdehyde dehydrogenase (acylating) activity
GO:0019859 ISS:UniProtKB P thymine metabolic process
GO:0006573 ISS:UniProtKB P valine metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR016162 Aldehyde dehydrogenase N-terminal domain
IPR015590 Aldehyde dehydrogenase domain
IPR016163 Aldehyde dehydrogenase, C-terminal
IPR016160 Aldehyde dehydrogenase, cysteine active site
IPR016161 Aldehyde/histidinol dehydrogenase
IPR010061 MeMal-semiAld_DH

UniProt Annotations

Entry Information

Gene Name
CG17896 gene product from transcript CG17896-RB
Protein Entry
Q7KW39_DROME
UniProt ID
Q7KW39
Species
Drosophila

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=B ; IsoId=Q7KW39-1; Sequence=Displayed; Note=No experimental confirmation available. ; Name=A ; IsoId=Q7KW39-2; Sequence=VSP_051919; Note=No experimental confirmation available. ;
Catalytic Activity 2-methyl-3-oxopropanoate + CoA + H(2)O + NAD(+) = propanoyl-CoA + HCO(3)(-) + NADH.
Catalytic Activity 3-oxopropanoate + CoA + NAD(P)(+) = acetyl-CoA + CO(2) + NAD(P)H.
Function Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity).
Sequence Caution Sequence=CAA15632.1; Type=Erroneous gene model prediction; Evidence= ;
Similarity Belongs to the aldehyde dehydrogenase family.
Subcellular Location Mitochondrion .
Subunit Homotetramer.

Identical and Related Proteins

Unique RefSeq proteins for LMP009123 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24638878 RefSeq NP_726672 511 CG17896, isoform A
24638876 RefSeq NP_569845 520 CG17896, isoform B

Identical Sequences to LMP009123 proteins

Reference Database Accession Length Protein Name
GI:24638878 EMBL CAB41309.1 511 EG:171D11.1 [Drosophila melanogaster]
GI:24638878 gnl FlyBase 511 CG17896, isoform A [Drosophila melanogaster]
GI:24638876 gnl FlyBase 520 CG17896, isoform B [Drosophila melanogaster]
GI:24638876 SwissProt Q7KW39.1 520 RecName: Full=Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Short=MMSDH; Short=Malonate-semialdehyde dehydrogenase [acylating]; Flags: Precursor [Drosophila melanogaster]

Related Sequences to LMP009123 proteins

Reference Database Accession Length Protein Name
GI:24638876 EMBL CAA15632.1 552 EG:171D11.1 [Drosophila melanogaster]
GI:24638878 EMBL CAA15632.1 552 EG:171D11.1 [Drosophila melanogaster]
GI:24638876 GenBank EDW43707.1 520 GM19037 [Drosophila sechellia]
GI:24638876 GenBank EDX00788.1 520 GE16583 [Drosophila yakuba]
GI:24638878 GenBank EDX16758.1 517 GD16476 [Drosophila simulans]
GI:24638878 GenBank AFH55498.1 535 FI19805p1, partial [Drosophila melanogaster]
GI:24638876 GenBank AFH55498.1 535 FI19805p1, partial [Drosophila melanogaster]
GI:24638878 gnl FlyBase 520 CG17896, isoform B [Drosophila melanogaster]
GI:24638878 RefSeq NP_569845.2 520 CG17896, isoform B [Drosophila melanogaster]
GI:24638876 RefSeq XP_002040236.1 520 GM19037 [Drosophila sechellia]
GI:24638876 RefSeq XP_002099680.1 520 GE16583 [Drosophila yakuba]
GI:24638878 SwissProt Q7KW39.1 520 RecName: Full=Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Short=MMSDH; Short=Malonate-semialdehyde dehydrogenase [acylating]; Flags: Precursor [Drosophila melanogaster]