Gene/Proteome Database (LMPD)

LMPD ID
LMP009062
Gene ID
35398
Species
Drosophila melanogaster (Drosophila)
Gene Name
Hormone receptor-like in 39
Gene Symbol
Hr39
Synonyms
betaFTZ-E1; CG8676; dFTZ-F1beta; DHR30; DHR39; DHR39/Ftz-F1beta; Dmel\CG8676; EP(2)2490; fs(2)04443; fs(2)neo8; FTZ-F1B; ftz-f1beta; ftz-F1beta; FTZ-F1beta; HR39; i70; NR5B1
Alternate Names
CG8676-PA; CG8676-PB; CG8676-PC; CG8676-PD; Hr39-PA; Hr39-PB; Hr39-PC; Hr39-PD; NR5A-class nuclear hormone receptor; fs(2)04443; fs(2)neo8; hormone receptor-like in 39
Chromosome
2L
Map Location
39C-60

Proteins

hormone receptor-like in 39, isoform A
Refseq ID NP_476932
Protein GI 17136820
UniProt ID Q05192
mRNA ID NM_057584
Length 808
RefSeq Status REVIEWED
MPNMSSIKAEQQSGPLGGSSGYQVPVNMCTTTVANTTTTLGSSAGGATGSRHNVSVTNIKCELDELPSPNGNMVPVIANYVHGSLRIPLSGHSNHRESDSEEELASIENLKVRRRTAADKNGPRPMSWEGELSDTEVNGGEELMEMEPTIKSEVVPAVAPPQPVCALQPIKTELENIAGEMQIQEKCYPQSNTQHHAATKLKVAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPTNPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGTLYGNHHGIYRQMKVEASSTVPSSGQEAQNLSMDSASSNLDTVGLGSSHPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVASQQQPHQRLHQLNGFGGVPIPCSTSLPASPSLAGTSVKSEEMAETGKQSLRTGSVPPLLQEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSSSSGTSSGAHAQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
hormone receptor-like in 39, isoform B
Refseq ID NP_599123
Protein GI 19549535
UniProt ID Q05192
mRNA ID NM_134296
Length 808
RefSeq Status REVIEWED
MPNMSSIKAEQQSGPLGGSSGYQVPVNMCTTTVANTTTTLGSSAGGATGSRHNVSVTNIKCELDELPSPNGNMVPVIANYVHGSLRIPLSGHSNHRESDSEEELASIENLKVRRRTAADKNGPRPMSWEGELSDTEVNGGEELMEMEPTIKSEVVPAVAPPQPVCALQPIKTELENIAGEMQIQEKCYPQSNTQHHAATKLKVAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPTNPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGTLYGNHHGIYRQMKVEASSTVPSSGQEAQNLSMDSASSNLDTVGLGSSHPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVASQQQPHQRLHQLNGFGGVPIPCSTSLPASPSLAGTSVKSEEMAETGKQSLRTGSVPPLLQEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSSSSGTSSGAHAQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
hormone receptor-like in 39, isoform C
Refseq ID NP_476933
Protein GI 17136822
UniProt ID Q05192
mRNA ID NM_057585
Length 701
RefSeq Status REVIEWED
MPNMSSIKAEQQSGPLGGSSGYQVPVNMCTTTVANTTTTLGSSAGGATGSRHNVSVTNIKCELDELPSPNGNMVPVIANYVHGSLRIPLSGHSNHRESDSEEELASIENLKVRRRTAADKNGPRPMSWEGELSDTEVNGGEELMEMEPTIKSEVVPAVAPPQPVCALQPIKTELENIAGEMQIQEKCYPQSNTQHHAATKLKVAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPTNPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGTLYGNHHGIYRQMKVEASSTVPSSGQEAQNLSMDSASSNLDTVGLGSSHPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVASQQQPHQRLHQLNGFGGVPIPCSTSLPASPSLAGTSVKSEEMAETGKQSLRTGSVPPLLQEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSSSSGTSSGAHAQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQVSLCEL
hormone receptor-like in 39, isoform D
Refseq ID NP_724322
Protein GI 24585624
UniProt ID Q05192
mRNA ID NM_165364
Length 808
RefSeq Status REVIEWED
Protein sequence is identical to GI:19549535 (mRNA isoform)

Gene Information

Entrez Gene ID
35398
Gene Name
Hormone receptor-like in 39
Gene Symbol
Hr39
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:FlyBase C nucleus
GO:0000978 IDA:FlyBase F RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879 IDA:FlyBase F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0016321 IMP:FlyBase P female meiosis chromosome segregation
GO:0030522 IDA:GOC P intracellular receptor signaling pathway
GO:0045433 IMP:FlyBase P male courtship behavior, veined wing generated song production
GO:0060968 IMP:FlyBase P regulation of gene silencing
GO:0035211 IMP:FlyBase P spermathecum morphogenesis

REACTOME Pathway Links

REACTOME Pathway ID Description
6225926 Gene Expression
6226331 Generic Transcription Pathway
6226616 Nuclear Receptor transcription pathway

Domain Information

InterPro Annotations

Accession Description
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
Hormone receptor-like in 39
Protein Entry
FTF1B_DROME
UniProt ID
Q05192
Species
Drosophila

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=A; Synonyms=B; IsoId=Q05192-1; Sequence=Displayed; Name=C; Synonyms=DHR39-short; IsoId=Q05192-2; Sequence=VSP_003718, VSP_003719;
Developmental Stage Expressed at all stages. {ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.
Function Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand. {ECO:0000269|PubMed:8164672, ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.
Interaction Q86BY9:rig; NbExp=2; IntAct=EBI-75048, EBI-422757; O96757:stumps; NbExp=3; IntAct=EBI-75048, EBI-74922;
Similarity Belongs to the nuclear hormone receptor family. NR5 subfamily. {ECO:0000305}.
Similarity Contains 1 nuclear receptor DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00407}.
Subcellular Location Nucleus.
Subunit Monomer; forms a complex with ftz. {ECO:0000250}.
Tissue Specificity Expressed throughout the blastodermal layer in early embryos. At later stages, strong expression is observed in the brain, ventral cord and hindgut. {ECO:0000269|PubMed:8382937, ECO:0000269|PubMed:8479913}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009062 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17136820 RefSeq NP_476932 808 hormone receptor-like in 39, isoform A
19549535 RefSeq NP_599123 808 hormone receptor-like in 39, isoform B
17136822 RefSeq NP_476933 701 hormone receptor-like in 39, isoform C

Identical Sequences to LMP009062 proteins

Reference Database Accession Length Protein Name
GI:19549535 GenBank AAL39821.1 808 LD45021p [Drosophila melanogaster]
GI:19549535 GenBank ACL83731.1 808 Hr39-PA, partial [synthetic construct]
GI:17136820 GenBank ACL83731.1 808 Hr39-PA, partial [synthetic construct]
GI:19549535 gnl FlyBase 808 hormone receptor-like in 39, isoform A [Drosophila melanogaster]
GI:17136820 gnl FlyBase 808 hormone receptor-like in 39, isoform A [Drosophila melanogaster]
GI:19549535 gnl FlyBase 808 hormone receptor-like in 39, isoform D [Drosophila melanogaster]
GI:17136820 gnl FlyBase 808 hormone receptor-like in 39, isoform D [Drosophila melanogaster]
GI:17136822 gnl FlyBase 701 hormone receptor-like in 39, isoform C [Drosophila melanogaster]
GI:17136820 RefSeq NP_599123.1 808 hormone receptor-like in 39, isoform B [Drosophila melanogaster]
GI:17136820 RefSeq NP_724322.1 808 hormone receptor-like in 39, isoform D [Drosophila melanogaster]
GI:19549535 RefSeq NP_724322.1 808 hormone receptor-like in 39, isoform D [Drosophila melanogaster]
GI:17136820 SwissProt Q05192.3 808 RecName: Full=Nuclear hormone receptor FTZ-F1 beta; AltName: Full=Nuclear hormone receptor HR39; Short=dHR39; AltName: Full=Nuclear receptor subfamily 5 group B member 1 [Drosophila melanogaster]
GI:19549535 SwissProt Q05192.3 808 RecName: Full=Nuclear hormone receptor FTZ-F1 beta; AltName: Full=Nuclear hormone receptor HR39; Short=dHR39; AltName: Full=Nuclear receptor subfamily 5 group B member 1 [Drosophila melanogaster]

Related Sequences to LMP009062 proteins

Reference Database Accession Length Protein Name
GI:19549535 GenBank AAA28462.1 808 DHR39 [Drosophila melanogaster]
GI:17136820 GenBank AAA28462.1 808 DHR39 [Drosophila melanogaster]
GI:17136822 GenBank AAA28463.1 701 DHR39-short [Drosophila melanogaster]
GI:19549535 GenBank AAA28464.1 808 DHR39 [Drosophila melanogaster]
GI:17136820 GenBank AAA28464.1 808 DHR39 [Drosophila melanogaster]
GI:17136820 GenBank AAA28543.1 808 steroid receptor [Drosophila melanogaster]
GI:19549535 GenBank AAA28543.1 808 steroid receptor [Drosophila melanogaster]
GI:17136822 GenBank AAL39821.1 808 LD45021p [Drosophila melanogaster]
GI:19549535 GenBank EDV54447.1 808 GG21291 [Drosophila erecta]
GI:17136820 GenBank EDV54447.1 808 GG21291 [Drosophila erecta]
GI:19549535 GenBank EDX05725.1 808 GD24312 [Drosophila simulans]
GI:17136820 GenBank EDX05725.1 808 GD24312 [Drosophila simulans]
GI:17136822 GenBank ACL83731.1 808 Hr39-PA, partial [synthetic construct]
GI:17136822 gnl FlyBase 808 hormone receptor-like in 39, isoform A [Drosophila melanogaster]
GI:17136822 RefSeq NP_476932.1 808 hormone receptor-like in 39, isoform A [Drosophila melanogaster]
GI:17136822 RefSeq NP_599123.1 808 hormone receptor-like in 39, isoform B [Drosophila melanogaster]
GI:19549535 RefSeq XP_002080140.1 808 GD24312 [Drosophila simulans]
GI:17136820 RefSeq XP_002080140.1 808 GD24312 [Drosophila simulans]