Gene/Proteome Database (LMPD)

LMPD ID
LMP009009
Gene ID
46068
Species
Drosophila melanogaster (Drosophila)
Gene Name
Acyl-CoA synthetase long-chain
Gene Symbol
Acsl
Synonyms
7447; anon-WO0172774.173; CG8732; dAcsl; dFAC; Dmel\CG8732; FACS; FCS; l(2)05847; l(2)44DEa; l(2)7447; l(2)k05304; l(2)SH0465; l(2)SH2 0465
Chromosome
2R
Map Location
44D3-44D6

Proteins

Acyl-CoA synthetase long-chain, isoform A
Refseq ID NP_724695
Protein GI 24586634
UniProt ID Q8T3L1
mRNA ID NM_170615
Length 715
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471681 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform B
Refseq ID NP_652034
Protein GI 22026970
UniProt ID Q8T3L1
mRNA ID NM_143777
Length 715
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471681 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform C
Refseq ID NP_724696
Protein GI 24586636
UniProt ID A1Z7H3
mRNA ID NM_170616
Length 707
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471679 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform D
Refseq ID NP_001014512
Protein GI 62471689
UniProt ID A1Z7H2
mRNA ID NM_001014512
Length 717
RefSeq Status REVIEWED
MKYNSLSYCVMDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS
Acyl-CoA synthetase long-chain, isoform E
Refseq ID NP_001014511
Protein GI 62471687
UniProt ID Q8T3L1
mRNA ID NM_001014511
Length 715
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471681 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform F
Refseq ID NP_001014510
Protein GI 62471685
UniProt ID A1Z7H3
mRNA ID NM_001014510
Length 707
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471679 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform G
Refseq ID NP_001014509
Protein GI 62471683
UniProt ID A1Z7H3
mRNA ID NM_001014509
Length 707
RefSeq Status REVIEWED
Protein sequence is identical to GI:62471679 (mRNA isoform)
Acyl-CoA synthetase long-chain, isoform H
Refseq ID NP_001014508
Protein GI 62471681
UniProt ID Q8T3L1
mRNA ID NM_001014508
Length 715
RefSeq Status REVIEWED
MFIEDDAQMDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS
Acyl-CoA synthetase long-chain, isoform I
Refseq ID NP_001014507
Protein GI 62471679
UniProt ID A1Z7H3
mRNA ID NM_001014507
Length 707
RefSeq Status REVIEWED
MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS
Acyl-CoA synthetase long-chain, isoform J
Refseq ID NP_001260810
Protein GI 442622933
UniProt ID A1Z7H3
mRNA ID NM_001273881
Length 728
RefSeq Status REVIEWED
MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKIVRNDDNELTYRTTDPPRDVHVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS

Gene Information

Entrez Gene ID
46068
Gene Name
Acyl-CoA synthetase long-chain
Gene Symbol
Acsl
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:FlyBase C cytoplasm
GO:0005783 IDA:FlyBase C endoplasmic reticulum
GO:0005811 IDA:FlyBase C lipid particle
GO:0004467 IEA:UniProtKB-EC F long-chain fatty acid-CoA ligase activity
GO:0007411 IMP:FlyBase P axon guidance
GO:0061502 IMP:FlyBase P early endosome to recycling endosome transport
GO:0030514 IMP:FlyBase P negative regulation of BMP signaling pathway
GO:0045886 IMP:FlyBase P negative regulation of synaptic growth at neuromuscular junction
GO:0007399 IMP:FlyBase P nervous system development
GO:0022008 IMP:FlyBase P neurogenesis
GO:0010890 IMP:FlyBase P positive regulation of sequestering of triglyceride
GO:0035282 IMP:FlyBase P segmentation
GO:0007268 IMP:FlyBase P synaptic transmission

KEGG Pathway Links

KEGG Pathway ID Description
dme00061 Fatty acid biosynthesis
ko00061 Fatty acid biosynthesis
dme00071 Fatty acid degradation
ko00071 Fatty acid degradation
dme01212 Fatty acid metabolism
ko01212 Fatty acid metabolism
dme01100 Metabolic pathways
dme04146 Peroxisome
ko04146 Peroxisome
M00086 beta-Oxidation, acyl-CoA synthesis
dme_M00086 beta-Oxidation, acyl-CoA synthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
6226048 Fatty Acyl-CoA Biosynthesis
6225964 Fatty acid, triacylglycerol, and ketone body metabolism
6225882 Metabolism
6225965 Metabolism of lipids and lipoproteins
6226056 Synthesis of very long-chain fatty acyl-CoAs
6226049 Triglyceride Biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR025110 AMP-binding enzyme C-terminal domain
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
Acyl-CoA synthetase long-chain
Protein Entry
A1Z7H3_DROME
UniProt ID
Q8T3L1
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP009009 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
62471689 RefSeq NP_001014512 717 Acyl-CoA synthetase long-chain, isoform D
62471681 RefSeq NP_001014508 715 Acyl-CoA synthetase long-chain, isoform H
62471679 RefSeq NP_001014507 707 Acyl-CoA synthetase long-chain, isoform I
442622933 RefSeq NP_001260810 728 Acyl-CoA synthetase long-chain, isoform J

Identical Sequences to LMP009009 proteins

Reference Database Accession Length Protein Name
GI:62471681 EMBL CBF65075.1 715 unnamed protein product [Drosophila melanogaster]
GI:62471681 EMBL CBU89946.1 715 unnamed protein product [Drosophila melanogaster]
GI:62471681 GenBank ACL86230.1 715 l(2)44DEa-PA, partial [synthetic construct]
GI:62471681 GenBank ACL90960.1 715 l(2)44DEa-PA [synthetic construct]
GI:62471681 GenBank AGX56975.1 715 Sequence 14269 from patent US 8541208
GI:62471689 gnl FlyBase 717 Acyl-CoA synthetase long-chain, isoform D [Drosophila melanogaster]
GI:62471679 gnl FlyBase 707 Acyl-CoA synthetase long-chain, isoform F [Drosophila melanogaster]
GI:62471679 gnl FlyBase 707 Acyl-CoA synthetase long-chain, isoform G [Drosophila melanogaster]
GI:62471679 gnl FlyBase 707 Acyl-CoA synthetase long-chain, isoform I [Drosophila melanogaster]
GI:442622933 gnl FlyBase 728 Acyl-CoA synthetase long-chain, isoform J [Drosophila melanogaster]
GI:62471679 RefSeq NP_724696.1 707 Acyl-CoA synthetase long-chain, isoform C [Drosophila melanogaster]
GI:62471679 RefSeq NP_001014509.1 707 Acyl-CoA synthetase long-chain, isoform G [Drosophila melanogaster]
GI:62471679 RefSeq NP_001014510.1 707 Acyl-CoA synthetase long-chain, isoform F [Drosophila melanogaster]
GI:62471681 RefSeq NP_001014511.1 715 Acyl-CoA synthetase long-chain, isoform E [Drosophila melanogaster]

Related Sequences to LMP009009 proteins

Reference Database Accession Length Protein Name
GI:442622933 EMBL CBF65075.1 715 unnamed protein product [Drosophila melanogaster]
GI:442622933 GenBank EDW89380.1 736 GE19217 [Drosophila yakuba]
GI:62471681 GenBank EDW89380.1 736 GE19217 [Drosophila yakuba]
GI:62471681 GenBank EDX06214.1 715 GD10588 [Drosophila simulans]
GI:442622933 GenBank ACL86230.1 715 l(2)44DEa-PA, partial [synthetic construct]
GI:62471689 GenBank ACL86230.1 715 l(2)44DEa-PA, partial [synthetic construct]
GI:62471679 GenBank ACL86230.1 715 l(2)44DEa-PA, partial [synthetic construct]
GI:442622933 GenBank ACL90960.1 715 l(2)44DEa-PA [synthetic construct]
GI:62471679 GenBank ACL90960.1 715 l(2)44DEa-PA [synthetic construct]
GI:62471689 GenBank ACL90960.1 715 l(2)44DEa-PA [synthetic construct]
GI:62471679 GenBank AGX56975.1 715 Sequence 14269 from patent US 8541208
GI:62471689 GenBank AGX56975.1 715 Sequence 14269 from patent US 8541208
GI:442622933 GenBank AGX56975.1 715 Sequence 14269 from patent US 8541208
GI:62471679 gnl FlyBase 715 Acyl-CoA synthetase long-chain, isoform H [Drosophila melanogaster]
GI:62471689 gnl FlyBase 715 Acyl-CoA synthetase long-chain, isoform H [Drosophila melanogaster]
GI:62471681 gnl FlyBase 707 Acyl-CoA synthetase long-chain, isoform F [Drosophila melanogaster]
GI:62471681 RefSeq NP_724696.1 707 Acyl-CoA synthetase long-chain, isoform C [Drosophila melanogaster]
GI:62471679 RefSeq NP_001014508.1 715 Acyl-CoA synthetase long-chain, isoform H [Drosophila melanogaster]
GI:62471689 RefSeq NP_001014508.1 715 Acyl-CoA synthetase long-chain, isoform H [Drosophila melanogaster]
GI:62471679 RefSeq NP_001014511.1 715 Acyl-CoA synthetase long-chain, isoform E [Drosophila melanogaster]
GI:62471689 RefSeq NP_001014511.1 715 Acyl-CoA synthetase long-chain, isoform E [Drosophila melanogaster]
GI:442622933 RefSeq XP_002089668.1 736 GE19217 [Drosophila yakuba]
GI:62471681 RefSeq XP_002089668.1 736 GE19217 [Drosophila yakuba]
GI:62471681 RefSeq XP_002080629.1 715 GD10588 [Drosophila simulans]