Gene/Proteome Database (LMPD)

LMPD ID
LMP008994
Gene ID
40285
Species
Drosophila melanogaster (Drosophila)
Gene Name
knirps-like
Gene Symbol
knrl
Synonyms
CG4761; Dmel\CG4761; Knrl; NR0A2
Alternate Names
CG4761-PA; Knirps-related; knirps related; knirps-like; knrl-PA
Chromosome
3L
Map Location
77D4-77E1

Proteins

knirps-like
Refseq ID NP_788552
Protein GI 28574803
UniProt ID P13054
mRNA ID NM_176374
Length 647
RefSeq Status REVIEWED
MMNQDNPYAMNQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGECIINKKNRTACKACRLKKCLMVGMSKSGSRYGRRSNWFKIHCLLQENAVAAMAAHHNSQQAGGGSSGGSGGGQGMPNGVKGMSGVPPPAAAAAALGMLGHPGGYPGLYAVANAGGSSRSKEELMMLGLDGSVEYGSHKHPVVASPSVSSPDSHNSDSSVEVSSVRGNPLLHLGGKSNSGGSSSGADGSHSGGGGGGGGGVTPGRPPQMRKDLSPFLPLPFPGLASMPVMPPPAFLPPSHLLFPGYHPALYSHHQGLLKPTPEQQQAAVAAAAVQHLFNSSGAGQRFAPGTSPFANHQQHHKEEDQPAPARSPSTHANNNHLLTNGGAADELTKRFYLDAVLKSQQQSPPPTTKLPPHSKQDYSISALVTPNSESGRERVKSRQNEEDDEARADGIIDGAEHDDEEEDLVVSMTPPHSPAQQEERTPAGEDPRPSPGQDNPIDLSMKTTGSSLSSKSSSPEIEPETEISSDVEKNDTDDDDEDLKVTPEEEISVRETADPEIEEDHSSTTETAKTSIENTHNNNNSISNNNNNNNNNNNSILSDSEASETIKRKLDELIEASSENGKRLRLEAPVKVATSNALDLTTKV

Gene Information

Entrez Gene ID
40285
Gene Name
knirps-like
Gene Symbol
knrl
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0004879 NAS:FlyBase F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0043565 IEA:InterPro F sequence-specific DNA binding
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0046845 TAS:FlyBase P branched duct epithelial cell fate determination, open tracheal system
GO:0007427 TAS:FlyBase P epithelial cell migration, open tracheal system
GO:0030522 NAS:GOC P intracellular receptor signaling pathway
GO:0007424 TAS:FlyBase P open tracheal system development
GO:0007088 IMP:FlyBase P regulation of mitosis
GO:0035151 TAS:FlyBase P regulation of tube size, open tracheal system

REACTOME Pathway Links

REACTOME Pathway ID Description
6226616 Nuclear Receptor transcription pathway
6226765 PPARA activates gene expression
6226669 REV-ERBA represses gene expression
6226670 RORA activates circadian gene expression

Domain Information

InterPro Annotations

Accession Description
IPR008946 Nuclear hormone receptor, ligand-binding
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
knirps-like
Protein Entry
KNRL_DROME
UniProt ID
P13054
Species
Drosophila

Comments

Comment Type Description
Similarity Belongs to the nuclear hormone receptor family. NR0 subfamily. {ECO:0000305}.
Similarity Contains 1 nuclear receptor DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00407}.
Subcellular Location Nucleus.

Identical and Related Proteins

Unique RefSeq proteins for LMP008994 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
28574803 RefSeq NP_788552 647 knirps-like

Identical Sequences to LMP008994 proteins

Reference Database Accession Length Protein Name
GI:28574803 GenBank AAL68221.1 647 LD23140p [Drosophila melanogaster]
GI:28574803 GenBank ACL83715.1 647 knrl-PA, partial [synthetic construct]
GI:28574803 GenBank ACL92679.1 647 knrl-PA [synthetic construct]
GI:28574803 gnl FlyBase 647 knirps-like [Drosophila melanogaster]
GI:28574803 PRF - 647 knirps related gene [Drosophila sp.]
GI:28574803 SwissProt P13054.1 647 RecName: Full=Knirps-related protein; AltName: Full=Nuclear receptor subfamily 0 group A member 2 [Drosophila melanogaster]

Related Sequences to LMP008994 proteins

Reference Database Accession Length Protein Name
GI:28574803 GenBank EDV52546.1 643 GG13294 [Drosophila erecta]
GI:28574803 GenBank EDW44250.1 643 GM22199 [Drosophila sechellia]
GI:28574803 GenBank EDX11270.1 599 GD12173 [Drosophila simulans]
GI:28574803 RefSeq XP_001973520.1 643 GG13294 [Drosophila erecta]
GI:28574803 RefSeq XP_002040697.1 643 GM22199 [Drosophila sechellia]
GI:28574803 RefSeq XP_002085685.1 599 GD12173 [Drosophila simulans]