Gene/Proteome Database (LMPD)

LMPD ID
LMP008988
Gene ID
37360
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG30295 gene product from transcript CG30295-RB
Gene Symbol
Ipk1
Synonyms
CG15228; CG15229; CG15230; CG30295; Dmel\CG30295; dmIpk1
Chromosome
2R
Map Location
57B3-57B4

Proteins

Ipk1, isoform A
Refseq ID NP_611522
Protein GI 20304107
UniProt ID Q9W2Q7
mRNA ID NM_137678
Length 621
RefSeq Status REVIEWED
MTAERGPRSPGTGQKLRLRATEPMPQWTAKNLHALLDLPAAMELRQIELIYRAEGNANLVLALPQFKKVLRLPKMISSRLRQAAHQRHELADEVARPEGQRVSSERAGTENAGDLTMPDFMAYIGIMRRLLGNEFVCGADIVAIPKEDDRFWINEHIRAQRPVSRLDKEFVGPFGLLLPDVTQLPATFDVLLANLQAKGTTGDESGAAAGVGDGGGVGRGAGTRTKNRSAVRRLGDTYAIEIKPKQGWLQLASDVNDLFDLMPSGAVTKPKETTCNQEENEPSARDKCWCRFCSMQLLKMHNGKIKRLGHYCPLDLFSGTPSRMLDALDALLACPQNNLRVFQNSNLIYGDHANSISFDELSSRVFPGEIMVLIKHLLVACLLREYEHPESKRAEGSNQSQKQQQEQPEPEQLNQSRVSIAATETKAGAAGIGAANVVLPLGGRAAAPVVTAGQSSTRTRAAAATATTQRYTKVARVETTITRQAATSMAAGPASSSQLSGNVLATATATATATAMATSGRTETKTEPETPAEAASTTSRNVNQNESQKLNRNEPANQTQAQNNKTEIFRLPKNCVLQKILNLQLLVKVSQPIKLLPKLLSLCPFGFVYSACPPENLGNCR
Ipk1, isoform B
Refseq ID NP_001097387
Protein GI 161077289
UniProt ID A8DYK1
mRNA ID NM_001103917
Length 716
RefSeq Status REVIEWED
MTAERGPRSPGTGQKLRLRATEPMPQWTAKNLHALLDLPAAMELRQIELIYRAEGNANLVLALPQFKKVLRLPKMISSRLRQAAHQRHELADEVARPEGQRVSSERAGTENAGDLTMPDFMAYIGIMRRLLGNEFVCGADIVAIPKEDDRFWINEHIRAQRPVSRLDKEFVGPFGLLLPDVTQLPATFDVLLANLQAKGTTGDESGAAAGVGDGGGVGRGAGTRTKNRSAVRRLGDTYAIEIKPKQGWLQLASDVNDLFDLMPSGAVTKPKETTCNQEENEPSARDKCWCRFCSMQLLKMHNGKIKRLGHYCPLDLFSGTPSRMLDALDALLACPQNNLRVFQNSNLIYGDHANSISFDELSSRVFPGEIMVLIKHLLVACLLREYEHPESKRAEGSNQSQKQQQEQPEPEQLNQSRVSIAATETKAGAAGIGAANVVLPLGGRAAAPVVTAGQSSTRTRAAAATATTQRYTKVARVETTITRQAATSMAAGPASSSQLSGNVLATATATATATAMATSGRTETKTEPETPAEAASTTSRNVNQNESQKLNRNEPANQTQAQNNKTEIFRLPKNCVLQKILNLQLLVKRHFDFMWQSGYSDHSRPTYNSLRGLLAAIEGAGDEEFEPDEDQAYMLGATALDCSIMLTFQEIEIECETDCPADQSSDAALQPWCVSLLGHHFLTKLCVLDLDPKPDSHFHKFIAQTREIEKCRRALN
Ipk1, isoform C
Refseq ID NP_001261111
Protein GI 442624341
UniProt ID A8DYK1
mRNA ID NM_001274182
Length 715
RefSeq Status REVIEWED
MTAERGPRSPGTGQKLRLRATEPMPQWTAKNLHALLDLPAAMELRQIELIYRAEGNANLVLALPQFKKVLRLPKMISSRLRQAAHQRHELADEVARPEGQRVSSERAGTENAGDLTMPDFMAYIGIMRRLLGNEFVCGADIVAIPKEDDRFWINEHIRAQRPVSRLDKEFVGPFGLLLPDVTQLPATFDVLLANLQAKGTTGDESGAAAGVGDGGGVGRGAGTRTKNRSAVRRLGDTYAIEIKPKQGWLQLASDVNDLFDLMPSGAVTKPKETTCNQEENEPSARDKCWCRFCSMQLLKMHNGKIKRLGHYCPLDLFSGTPSRMLDALDALLACPQNNLRVFQNSNLIYGDHANSISFDELSSRVFPGEIMVLIKHLLVACLLREYEHPESKRAEGSNQSQKQQQEQPEPEQLNQSRVSIAATETKAGAAGIGAANVVLPLGGRAAAPVVTAGQSSTRTRAAAATATTQRYTKVARVETTITRQAATSMAAGPASSSQLSGNVLATATATATATAMATSGRTETKTEPETPAEAASTTSRNVNQNESQKLNRNEPANQTQAQNNKTEIFRLPKNCVLQKILNLQLLVKRHFDFMWQSGYSDHSRPTYNSLRGLLAAIEGAGDEEFEPDEDQAYMLGATALDCSIMLTFQEIEIECETDCPADQSDAALQPWCVSLLGHHFLTKLCVLDLDPKPDSHFHKFIAQTREIEKCRRALN
Ipk1, isoform D
Refseq ID NP_001286649
Protein GI 665402366
UniProt ID Q9W2Q7
mRNA ID NM_001299720
Length 576
RefSeq Status REVIEWED
MENSVHAVPCRPVVGFITHHTISATTFVLCHNSNRSRSRSSDNLAKDLDPNPCETMAKGTTGDESGAAAGVGDGGGVGRGAGTRTKNRSAVRRLGDTYAIEIKPKQGWLQLASDVNDLFDLMPSGAVTKPKETTCNQEENEPSARDKCWCRFCSMQLLKMHNGKIKRLGHYCPLDLFSGTPSRMLDALDALLACPQNNLRVFQNSNLIYGDHANSISFDELSSRVFPGEIMVLIKHLLVACLLREYEHPESKRAEGSNQSQKQQQEQPEPEQLNQSRVSIAATETKAGAAGIGAANVVLPLGGRAAAPVVTAGQSSTRTRAAAATATTQRYTKVARVETTITRQAATSMAAGPASSSQLSGNVLATATATATATAMATSGRTETKTEPETPAEAASTTSRNVNQNESQKLNRNEPANQTQAQNNKTEIFRLPKNCVLQKILNLQLLVKRHFDFMWQSGYSDHSRPTYNSLRGLLAAIEGAGDEEFEPDEDQAYMLGATALDCSIMLTFQEIEIECETDCPADQSSDAALQPWCVSLLGHHFLTKLCVLDLDPKPDSHFHKFIAQTREIEKCRRALN

Gene Information

Entrez Gene ID
37360
Gene Name
CG30295 gene product from transcript CG30295-RB
Gene Symbol
Ipk1
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0035299 IMP:UniProtKB F inositol pentakisphosphate 2-kinase activity
GO:0032958 IDA:FlyBase P inositol phosphate biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
dme00562 Inositol phosphate metabolism
ko00562 Inositol phosphate metabolism
dme01100 Metabolic pathways
dme04070 Phosphatidylinositol signaling system
ko04070 Phosphatidylinositol signaling system

REACTOME Pathway Links

REACTOME Pathway ID Description
6226923 Inositol phosphate metabolism
6225882 Metabolism
6226925 Synthesis of IPs in the nucleus
6226926 Synthesis of pyrophosphates in the cytosol

Domain Information

InterPro Annotations

Accession Description
IPR009286 Inositol-pentakisphosphate 2-kinase

UniProt Annotations

Entry Information

Gene Name
CG30295 gene product from transcript CG30295-RB
Protein Entry
A8DYK1_DROME
UniProt ID
Q9W2Q7
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity ATP + 1D-myo-inositol 1,3,4,5,6- pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate.
Domain The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
Function Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). {ECO:0000269|PubMed:15322119}.
Similarity Belongs to the IPK1 type 2 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008988 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
20304107 RefSeq NP_611522 621 Ipk1, isoform A
161077289 RefSeq NP_001097387 716 Ipk1, isoform B
442624341 RefSeq NP_001261111 715 Ipk1, isoform C
665402366 RefSeq NP_001286649 576 Ipk1, isoform D

Identical Sequences to LMP008988 proteins

Reference Database Accession Length Protein Name
GI:20304107 GenBank AAL27632.1 621 GH07317p [Drosophila melanogaster]
GI:20304107 GenBank ACL85243.1 621 Ipk1-PA, partial [synthetic construct]
GI:20304107 GenBank ACL90110.1 621 Ipk1-PA [synthetic construct]
GI:20304107 gnl FlyBase 621 Ipk1, isoform A [Drosophila melanogaster]
GI:161077289 gnl FlyBase 716 Ipk1, isoform B [Drosophila melanogaster]
GI:442624341 gnl FlyBase 715 Ipk1, isoform C [Drosophila melanogaster]
GI:665402366 gnl FlyBase 576 Ipk1, isoform D [Drosophila melanogaster]
GI:20304107 SwissProt Q9W2Q7.2 621 RecName: Full=Inositol-pentakisphosphate 2-kinase; AltName: Full=Inositol-1,3,4,5,6-pentakisphosphate 2-kinase; AltName: Full=Ins(1,3,4,5,6)P5 2-kinase; Short=DmIpk1; Short=InsP5 2-kinase [Drosophila melanogaster]

Related Sequences to LMP008988 proteins

Reference Database Accession Length Protein Name
GI:442624341 GenBank EDW56533.1 714 GM15781 [Drosophila sechellia]
GI:20304107 GenBank EDW56533.1 714 GM15781 [Drosophila sechellia]
GI:665402366 GenBank EDW56533.1 714 GM15781 [Drosophila sechellia]
GI:161077289 GenBank EDW56533.1 714 GM15781 [Drosophila sechellia]
GI:442624341 GenBank EDX07975.1 667 GD11544 [Drosophila simulans]
GI:161077289 GenBank EDX07975.1 667 GD11544 [Drosophila simulans]
GI:665402366 gnl FlyBase 716 Ipk1, isoform B [Drosophila melanogaster]
GI:442624341 gnl FlyBase 716 Ipk1, isoform B [Drosophila melanogaster]
GI:20304107 gnl FlyBase 716 Ipk1, isoform B [Drosophila melanogaster]
GI:161077289 gnl FlyBase 715 Ipk1, isoform C [Drosophila melanogaster]
GI:665402366 gnl FlyBase 715 Ipk1, isoform C [Drosophila melanogaster]
GI:20304107 gnl FlyBase 715 Ipk1, isoform C [Drosophila melanogaster]
GI:20304107 RefSeq NP_001097387.1 716 Ipk1, isoform B [Drosophila melanogaster]
GI:442624341 RefSeq NP_001097387.1 716 Ipk1, isoform B [Drosophila melanogaster]
GI:665402366 RefSeq NP_001097387.1 716 Ipk1, isoform B [Drosophila melanogaster]
GI:161077289 RefSeq XP_002039668.1 714 GM15781 [Drosophila sechellia]
GI:665402366 RefSeq XP_002039668.1 714 GM15781 [Drosophila sechellia]
GI:20304107 RefSeq XP_002039668.1 714 GM15781 [Drosophila sechellia]
GI:442624341 RefSeq XP_002039668.1 714 GM15781 [Drosophila sechellia]
GI:442624341 RefSeq XP_002082390.1 667 GD11544 [Drosophila simulans]
GI:161077289 RefSeq XP_002082390.1 667 GD11544 [Drosophila simulans]
GI:161077289 RefSeq NP_001261111.1 715 Ipk1, isoform C [Drosophila melanogaster]
GI:20304107 RefSeq NP_001261111.1 715 Ipk1, isoform C [Drosophila melanogaster]
GI:665402366 RefSeq NP_001261111.1 715 Ipk1, isoform C [Drosophila melanogaster]