Gene/Proteome Database (LMPD)

LMPD ID
LMP008965
Gene ID
40148
Species
Drosophila melanogaster (Drosophila)
Gene Name
G protein beta-subunit 76C
Gene Symbol
Gbeta76C
Synonyms
CG8770; DGqbeta; Dmel\CG8770; eGbeta; eye Gbeta; Galpha76C; gbe; Gbe; Gbeta; Gbetae; Gbeta[[e]]; Gbeta{e}; Gqbeta; G[q]; G[[beta76C]]; G[[beta]]; G[[beta]]e
Alternate Names
CG8770-PA; G protein beta-subunit 76C; G[[beta]] eye; Gbeta76C-PA; guanine nucleotide regulatory protein beta subunit
Chromosome
3L
Map Location
76C1-76C1

Proteins

G protein beta-subunit 76C
Refseq ID NP_523720
Protein GI 24666913
UniProt ID P29829
mRNA ID NM_078996
Length 346
RefSeq Status REVIEWED
MPKIDPETQKLYDEINGMIQKFKDDQKSKADCTLADKCGDMGDVPKIRFSSKKILKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGNFVACGGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLDDGHLITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQKNTGFTSCALSTSGRYLMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCLASTSWDQQVRLWL

Gene Information

Entrez Gene ID
40148
Gene Name
G protein beta-subunit 76C
Gene Symbol
Gbeta76C
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:FlyBase C cytoplasm
GO:0005834 IDA:FlyBase C heterotrimeric G-protein complex
GO:0005886 IDA:FlyBase C plasma membrane
GO:0016028 IDA:FlyBase C rhabdomere
GO:0003924 IMP:FlyBase F GTPase activity
GO:0046982 IPI:FlyBase F protein heterodimerization activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0007186 NAS:FlyBase P G-protein coupled receptor signaling pathway
GO:0006184 IMP:GOC P GTP catabolic process
GO:0007202 IMP:FlyBase P activation of phospholipase C activity
GO:0016059 IMP:FlyBase P deactivation of rhodopsin mediated signaling
GO:0007602 IDA:FlyBase P phototransduction
GO:0016056 IMP:FlyBase P rhodopsin mediated signaling pathway
GO:0007601 IEA:UniProtKB-KW P visual perception

KEGG Pathway Links

KEGG Pathway ID Description
dme04745 Phototransduction - fly
ko04745 Phototransduction - fly

REACTOME Pathway Links

REACTOME Pathway ID Description
6226825 Activation of G protein gated Potassium channels
6226824 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Domain Information

InterPro Annotations

Accession Description
IPR020472 G-protein beta WD-40 repeat
IPR001632 G-protein, beta subunit
IPR016346 Guanine nucleotide-binding protein, beta subunit
IPR019775 WD40 repeat, conserved site
IPR017986 WD40-repeat-containing domain
IPR015943 WD40/YVTN repeat-like-containing domain
IPR001680 WD40_repeat

UniProt Annotations

Entry Information

Gene Name
G protein beta-subunit 76C
Protein Entry
GBB2_DROME
UniProt ID
P29829
Species
Drosophila

Comments

Comment Type Description
Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Interaction Q9NFZ3:Ggamma30A; NbExp=2; IntAct=EBI-128499, EBI-2695634;
Similarity Belongs to the WD repeat G protein beta family. {ECO:0000305}.
Similarity Contains 7 WD repeats. {ECO:0000255|PROSITE- ProRule:PRU00221}.
Subunit G proteins are composed of 3 units, alpha, beta and gamma.
Tissue Specificity In the Drosophila compound eye.

Identical and Related Proteins

Unique RefSeq proteins for LMP008965 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24666913 RefSeq NP_523720 346 G protein beta-subunit 76C

Identical Sequences to LMP008965 proteins

Reference Database Accession Length Protein Name
GI:24666913 GenBank EDX11112.1 346 GD14823 [Drosophila simulans]
GI:24666913 GenBank ACL84445.1 346 Gbeta76C-PA, partial [synthetic construct]
GI:24666913 GenBank ACL89397.1 346 Gbeta76C-PA [synthetic construct]
GI:24666913 RefSeq XP_002043605.1 346 GM19633 [Drosophila sechellia]
GI:24666913 RefSeq XP_002095577.1 346 GE19620 [Drosophila yakuba]
GI:24666913 RefSeq XP_002085527.1 346 GD14823 [Drosophila simulans]

Related Sequences to LMP008965 proteins

Reference Database Accession Length Protein Name
GI:24666913 GenBank AAA73103.1 346 unnamed protein product [Drosophila melanogaster]
GI:24666913 GenBank EDV40847.1 346 GF23715 [Drosophila ananassae]
GI:24666913 GenBank EDV52401.1 346 GG16054 [Drosophila erecta]
GI:24666913 RefSeq XP_001958041.1 346 GF23715 [Drosophila ananassae]
GI:24666913 RefSeq XP_001973375.1 346 GG16054 [Drosophila erecta]
GI:24666913 RefSeq XP_002008456.1 346 GI11805 [Drosophila mojavensis]