Gene/Proteome Database (LMPD)

LMPD ID
LMP008944
Gene ID
37517
Species
Drosophila melanogaster (Drosophila)
Gene Name
Synaptojanin
Gene Symbol
Synj
Synonyms
CG6562; Dmel\CG6562; IPP; synj
Chromosome
2R
Map Location
58B4-58B4

Proteins

synaptojanin, isoform A
Refseq ID NP_726155
Protein GI 24657576
UniProt ID Q5U0V7
mRNA ID NM_166505
Length 1218
RefSeq Status REVIEWED
Protein sequence is identical to GI:386768412 (mRNA isoform)
synaptojanin, isoform B
Refseq ID NP_569729
Protein GI 18497296
UniProt ID Q5U0V7
mRNA ID NM_130462
Length 1218
RefSeq Status REVIEWED
Protein sequence is identical to GI:386768412 (mRNA isoform)
synaptojanin, isoform C
Refseq ID NP_001246454
Protein GI 386768412
UniProt ID Q5U0V7
mRNA ID NM_001259525
Length 1218
RefSeq Status REVIEWED
MAMSKVIRVLEKSIAPSPHSVLLEHRNKSDSILFESHAVALLTQQETDVIRKQYTKVCDAYGCLGALQLNAGESTVLFLVLVTGCVSMGKIGDIEIFRITQTTFVSLQNAAPNEDKISEVRKLLNSGTFYFAHTNASASASGASSYRFDITLCAQRRQQTQETDNRFFWNRMMHIHLMRFGIDCQSWLLQAMCGSVEVRTVYIGAKQARAAIISRLSCERAGTRFNVRGTNDEGYVANFVETEQVIYVDGDVTSYVQTRGSVPLFWEQPGVQVGSHKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKEGEAMLSNEFQRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFHASNGQVLREQFGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNISRFEEIFRQMWINNGNEVSKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAFPMGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLESSATGDEDGPTIYDENVMSALITELSKMGEVTLVRYVEDTMWVTFRDGESALNASSKKSIQVCGLDLILELKSKDWQHLVDSEIELCTTNTIPLCANPVEHAQLLQAITPELPQRPKQPPTRPPARPPMPMSPKNSPRHLPHVGVISIVPKPAKPPMPPQPQSQPLIPSPLQPQVAPPRPPAMDTTPSSKSQSPTELVSASSSTSSSGKTSPTAPAVLSGPPTPPRQMQSKQATPVSTPTRQVGSPKDPIPSDTAYETASNIYEEIQEDVPAPRHPPPAGPPPVIGAPMGPPPPLPNRRGPPPIPNRSGNAPPLPTRPANN

Gene Information

Entrez Gene ID
37517
Gene Name
Synaptojanin
Gene Symbol
Synj
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0043195 IDA:FlyBase C terminal bouton
GO:0012506 IDA:FlyBase C vesicle membrane
GO:0046030 NAS:FlyBase F inositol trisphosphate phosphatase activity
GO:0052659 IEA:UniProtKB-EC F inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:0052658 IEA:UniProtKB-EC F inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0004445 IDA:FlyBase F inositol-polyphosphate 5-phosphatase activity
GO:0000166 IEA:InterPro F nucleotide binding
GO:0004439 IEA:UniProtKB-EC F phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0016311 NAS:FlyBase P dephosphorylation
GO:0048790 IMP:FlyBase P maintenance of presynaptic active zone structure
GO:0007269 NAS:FlyBase P neurotransmitter secretion
GO:0046856 IEA:InterPro P phosphatidylinositol dephosphorylation
GO:0050803 IMP:FlyBase P regulation of synapse structure and activity
GO:0048488 IMP:FlyBase P synaptic vesicle endocytosis

KEGG Pathway Links

KEGG Pathway ID Description
dme00562 Inositol phosphate metabolism
ko00562 Inositol phosphate metabolism
dme01100 Metabolic pathways
dme04070 Phosphatidylinositol signaling system
ko04070 Phosphatidylinositol signaling system

REACTOME Pathway Links

REACTOME Pathway ID Description
6226923 Inositol phosphate metabolism
6225882 Metabolism
6225965 Metabolism of lipids and lipoproteins
6226887 PI Metabolism
6226059 Phospholipid metabolism
6226924 Synthesis of IP2, IP, and Ins in the cytosol
6226922 Synthesis of IP3 and IP4 in the cytosol
6226907 Synthesis of PIPs at the plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR015047 Domain of unknown function DUF1866
IPR005135 Endonuclease/exonuclease/phosphatase
IPR000300 Inositol polyphosphate-related phosphatase
IPR012677 Nucleotide-binding alpha-beta plait domain
IPR002013 SAC domain

UniProt Annotations

Entry Information

Gene Name
Synaptojanin
Protein Entry
Q5U0V7_DROME
UniProt ID
Q5U0V7
Species
Drosophila

Identical and Related Proteins

Unique RefSeq proteins for LMP008944 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
386768412 RefSeq NP_001246454 1218 synaptojanin, isoform C

Identical Sequences to LMP008944 proteins

Reference Database Accession Length Protein Name
GI:386768412 EMBL CAR81402.1 1218 unnamed protein product [Drosophila melanogaster]
GI:386768412 EMBL CBX84864.1 1218 unnamed protein product [Drosophila melanogaster]
GI:386768412 GenBank AAV37020.1 1218 GH06496p [Drosophila melanogaster]
GI:386768412 gnl FlyBase 1218 synaptojanin, isoform C [Drosophila melanogaster]
GI:386768412 RefSeq NP_569729.1 1218 synaptojanin, isoform B [Drosophila melanogaster]
GI:386768412 RefSeq NP_726155.1 1218 synaptojanin, isoform A [Drosophila melanogaster]

Related Sequences to LMP008944 proteins

Reference Database Accession Length Protein Name
GI:386768412 GenBank JAB93287.1 1240 Synaptojanin-1 [Ceratitis capitata]
GI:386768412 GenBank JAB93288.1 1240 Synaptojanin-1 [Ceratitis capitata]
GI:386768412 gnl WGS:AADE 1239 GA19686 [Drosophila pseudoobscura pseudoobscura]
GI:386768412 RefSeq XP_001361702.1 1239 GA19686 [Drosophila pseudoobscura pseudoobscura]
GI:386768412 RefSeq XP_004534809.1 1240 PREDICTED: synaptojanin-1-like isoform X2 [Ceratitis capitata]
GI:386768412 RefSeq XP_005187417.1 1231 PREDICTED: synaptojanin-1-like [Musca domestica]