Gene/Proteome Database (LMPD)

LMPD ID
LMP008887
Gene ID
39988
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG7430 gene product from transcript CG7430-RA
Gene Symbol
CG7430
Synonyms
Dmel\CG7430; E3
Chromosome
3L
Map Location
75A4-75A4

Proteins

CG7430, isoform A
Refseq ID NP_649017
Protein GI 21358499
UniProt ID Q9VVL7
mRNA ID NM_140760
Length 504
RefSeq Status REVIEWED
Protein sequence is identical to GI:442633125 (mRNA isoform)
CG7430, isoform B
Refseq ID NP_001262000
Protein GI 442633125
UniProt ID Q9VVL7
mRNA ID NM_001275071
Length 504
RefSeq Status REVIEWED
MQFTLRHVVSAVAKTPLRTNAAILGALNARCYSSTHEADIVVIGSGPGGYVAAIKAAQMGMKTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLEKRGISCGSVSLDLEKLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKTKNILIATGSEVTPFPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSVENAKSGEKEEIQCDALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGDCIHGPMLAHKAEDEGLITIEGINGGHVHIDYNCVPSVVYTHPEVAWVGKSEEQLKQEGVAYKVGKFPFLANSRAKTNNDTDGFVKVLADQATDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSEALREANVAAAFGKPINF

Gene Information

Entrez Gene ID
39988
Gene Name
CG7430 gene product from transcript CG7430-RA
Gene Symbol
CG7430
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005811 IDA:FlyBase C lipid particle
GO:0004148 IEA:UniProtKB-EC F dihydrolipoyl dehydrogenase activity
GO:0050660 IEA:InterPro F flavin adenine dinucleotide binding
GO:0045454 IEA:InterPro P cell redox homeostasis

Domain Information

InterPro Annotations

Accession Description
IPR006258 Dihydrolipoamide dehydrogenase
IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase
IPR016156 FAD/NAD-linked reductase, dimerisation domain
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain
IPR001327 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain
IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site
IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

UniProt Annotations

Entry Information

Gene Name
CG7430 gene product from transcript CG7430-RA
Protein Entry
Q9VVL7_DROME
UniProt ID
Q9VVL7
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity Protein N(6)-(dihydrolipoyl)lysine + NAD(+) = protein N(6)-(lipoyl)lysine + NADH.
Cofactor Note=Binds 1 FAD per subunit. ;
Miscellaneous The active site is a redox-active disulfide bond.
Similarity Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Identical and Related Proteins

Unique RefSeq proteins for LMP008887 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
442633125 RefSeq NP_001262000 504 CG7430, isoform B

Identical Sequences to LMP008887 proteins

Reference Database Accession Length Protein Name
GI:442633125 GenBank AAL13969.1 504 LP04889p [Drosophila melanogaster]
GI:442633125 GenBank ABL48108.1 504 Sequence 843 from patent US 7135558
GI:442633125 GenBank ACL85798.1 504 CG7430-PA, partial [synthetic construct]
GI:442633125 gnl FlyBase 504 CG7430, isoform A [Drosophila melanogaster]
GI:442633125 gnl FlyBase 504 CG7430, isoform B [Drosophila melanogaster]
GI:442633125 RefSeq NP_649017.1 504 CG7430, isoform A [Drosophila melanogaster]

Related Sequences to LMP008887 proteins

Reference Database Accession Length Protein Name
GI:442633125 GenBank AAU61688.1 623 Sequence 42633 from patent US 6703491
GI:442633125 GenBank EDW41934.1 504 GM25722 [Drosophila sechellia]
GI:442633125 GenBank EDX10911.1 504 GD14729 [Drosophila simulans]
GI:442633125 RefSeq XP_002030948.1 504 GM25722 [Drosophila sechellia]
GI:442633125 RefSeq XP_002094955.1 504 GE19931 [Drosophila yakuba]
GI:442633125 RefSeq XP_002085326.1 504 GD14729 [Drosophila simulans]