Gene/Proteome Database (LMPD)

LMPD ID
LMP008328
Gene ID
181169
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein B0272.3
Gene Symbol
B0272.3
Synonyms
CELE_B0272.3
Alternate Names
Protein B0272.3
Chromosome
X
EC Number
1.1.1.35

Proteins

Protein B0272.3
Refseq ID NP_509584
Protein GI 17549919
UniProt ID P41938
mRNA ID NM_077183
Length 309
RefSeq Status REVIEWED
MLSSTCTAAVRGLSTTAQLSKINNVTIIGAGLMGSGIAQVSANAKLNVTVVDSNQSALEKAQQGIANSLKRVAKKKHADDAAAQTALVSSVLDRIKMSTNVSDSVKDADLVIEAIVENIDIKRKLFAEVEVAAKPTTLITTNTSSLRLADIGLNLKDKSRFGGLHFFNPVPMMKLLEVVRHTETSDATFNQLVDYGKTVGKTTVACKDTPGFIVNRLLVPYMFEALRLYERGDASMEDIDVAMKLGAGYPMGPFELSDYVGLDTCKFIMDGWHAQYPEEVAFTPSPLLNSLVDSGKNGRKSGEGFYKYK

Gene Information

Entrez Gene ID
181169
Gene Name
Protein B0272.3
Gene Symbol
B0272.3
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0003857 IEA:UniProtKB-EC F 3-hydroxyacyl-CoA dehydrogenase activity
GO:0070403 IEA:InterPro F NAD+ binding
GO:0006635 IEA:UniProtKB-UniPathway P fatty acid beta-oxidation

KEGG Pathway Links

KEGG Pathway ID Description
cel_M00085 Fatty acid biosynthesis, elongation, mitochondria
cel00310 Lysine degradation
cel00380 Tryptophan metabolism
cel_M00087 beta-Oxidation

Domain Information

InterPro Annotations

Accession Description
IPR022694 3-hydroxyacyl-CoA dehydrogenase
IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR013328 Dehydrogenase, multihelical
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
Protein B0272.3
Protein Entry
HCDH2_CAEEL
UniProt ID
P41938
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
Pathway Lipid metabolism; fatty acid beta-oxidation.
Similarity Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. {ECO:0000305}.
Subcellular Location Mitochondrion matrix {ECO:0000250}.
Subunit Homodimer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008328 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17549919 RefSeq NP_509584 309 Protein B0272.3

Identical Sequences to LMP008328 proteins

Reference Database Accession Length Protein Name
GI:17549919 GenBank ABZ32917.1 309 Sequence 6855 from patent US 7314974
GI:17549919 GenBank AEQ84585.1 309 Sequence 79 from patent US 8039587
GI:17549919 GenBank AEU53448.1 309 Sequence 79 from patent US 8062891
GI:17549919 GenBank AGO72401.1 309 Sequence 79 from patent US 8470972
GI:17549919 GenBank AGU32392.1 309 Sequence 79 from patent US 8507277
GI:17549919 GenBank AGX48296.1 309 Sequence 79 from patent US 8541550

Related Sequences to LMP008328 proteins

Reference Database Accession Length Protein Name
GI:17549919 EMBL CAP34252.1 309 Protein CBG16139 [Caenorhabditis briggsae]
GI:17549919 GenBank EFO97402.1 309 hypothetical protein CRE_16645 [Caenorhabditis remanei]
GI:17549919 GenBank ADY44579.1 315 3-hydroxyacyl-CoA dehydrogenase [Ascaris suum]
GI:17549919 GenBank EGT58024.1 309 hypothetical protein CAEBREN_09836 [Caenorhabditis brenneri]
GI:17549919 RefSeq XP_002643477.1 309 Hypothetical protein CBG16139 [Caenorhabditis briggsae]
GI:17549919 RefSeq XP_003106796.1 309 hypothetical protein CRE_16645 [Caenorhabditis remanei]