Gene/Proteome Database (LMPD)

LMPD ID
LMP008247
Gene ID
178122
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein FAT-6
Gene Symbol
fat-6
Synonyms
CELE_VZK822L.1
Alternate Names
Protein FAT-6
Chromosome
IV
EC Number
1.14.19.-

Proteins

Protein FAT-6, isoform a
Refseq ID NP_001255595
Protein GI 392900992
UniProt ID G5EGN2
mRNA ID NM_001268666
Length 339
RefSeq Status REVIEWED
MTVKTRSNIAKKIEKDGGPETQYLAVDPNEIIQLQEESKKIPYKMEIVWRNVALFAALHFAAAIGLYQLIFEAKWQTVIFTFLLYVFGGFGITAGAHRLWSHKSYKATTPMRIFLMILNNIALQNDVIEWARDHRCHHKWTDTDADPHNTTRGFFFAHMGWLLVRKHPQVKEQGAKLDMSDLLSDPVLVFQRKHYFPLVILCCFILPTIIPVYFWKETAFIAFYTAGTFRYCFTLHATWCINSAAHYFGWKPYDSSITPVENVFTTIAAVGEGGHNFHHTFPQDYRTSEYSLKYNWTRVLIDTAAALGLVYDRKTACDEIIGRQVSNHGCDIQRGKSIM
Protein FAT-6, isoform b
Refseq ID NP_001255596
Protein GI 392900994
UniProt ID G5EGN2
mRNA ID NM_001268667
Length 295
RefSeq Status REVIEWED
MEIVWRNVALFAALHFAAAIGLYQLIFEAKWQTVIFTFLLYVFGGFGITAGAHRLWSHKSYKATTPMRIFLMILNNIALQNDVIEWARDHRCHHKWTDTDADPHNTTRGFFFAHMGWLLVRKHPQVKEQGAKLDMSDLLSDPVLVFQRKHYFPLVILCCFILPTIIPVYFWKETAFIAFYTAGTFRYCFTLHATWCINSAAHYFGWKPYDSSITPVENVFTTIAAVGEGGHNFHHTFPQDYRTSEYSLKYNWTRVLIDTAAALGLVYDRKTACDEIIGRQVSNHGCDIQRGKSIM
Protein FAT-6, isoform c
Refseq ID NP_001255597
Protein GI 392900996
UniProt ID G5EGN2
mRNA ID NM_001268668
Length 229
RefSeq Status REVIEWED
MRIFLMILNNIALQNDVIEWARDHRCHHKWTDTDADPHNTTRGFFFAHMGWLLVRKHPQVKEQGAKLDMSDLLSDPVLVFQRKHYFPLVILCCFILPTIIPVYFWKETAFIAFYTAGTFRYCFTLHATWCINSAAHYFGWKPYDSSITPVENVFTTIAAVGEGGHNFHHTFPQDYRTSEYSLKYNWTRVLIDTAAALGLVYDRKTACDEIIGRQVSNHGCDIQRGKSIM

Gene Information

Entrez Gene ID
178122
Gene Name
Protein FAT-6
Gene Symbol
fat-6
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030176 ISS:WormBase C integral component of endoplasmic reticulum membrane
GO:0004768 IGI:WormBase F stearoyl-CoA 9-desaturase activity
GO:0045087 IEP:WormBase P innate immune response
GO:0042759 IGI:WormBase P long-chain fatty acid biosynthetic process
GO:0007275 IGI:WormBase P multicellular organismal development

KEGG Pathway Links

KEGG Pathway ID Description
cel01040 Biosynthesis of unsaturated fatty acids
ko01040 Biosynthesis of unsaturated fatty acids
cel01212 Fatty acid metabolism
ko01212 Fatty acid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR005804 Fatty acid desaturase, type 1
IPR015876 Fatty acid desaturase, type 1, core

UniProt Annotations

Entry Information

Gene Name
Protein FAT-6
Protein Entry
FAT6_CAEEL
UniProt ID
G5EGN2
Species
C. elegans

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=a; IsoId=G5EGN2-1; Sequence=Displayed; Name=b; IsoId=G5EGN2-2; Sequence=VSP_047791; Name=c; IsoId=G5EGN2-3; Sequence=VSP_047790;
Domain The histidine box domains may contain the active site and/or be involved in metal ion binding. {ECO:0000250}.
Function Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. {ECO:0000269|PubMed:10872837, ECO:0000269|PubMed:16839188}.
Similarity Belongs to the fatty acid desaturase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008247 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
392900992 RefSeq NP_001255595 339 Protein FAT-6, isoform a
392900994 RefSeq NP_001255596 295 Protein FAT-6, isoform b
392900996 RefSeq NP_001255597 229 Protein FAT-6, isoform c

Identical Sequences to LMP008247 proteins

Reference Database Accession Length Protein Name
GI:392900992 EMBL CAB08356.1 339 Protein FAT-6, isoform a [Caenorhabditis elegans]
GI:392900992 EMBL CAD20542.1 339 unnamed protein product [Caenorhabditis elegans]
GI:392900994 EMBL CBK19477.1 295 Protein FAT-6, isoform b [Caenorhabditis elegans]
GI:392900996 EMBL CBK19478.1 229 Protein FAT-6, isoform c [Caenorhabditis elegans]
GI:392900992 GenBank AAF97550.1 339 stearoyl-CoA desaturase FAT-6 [Caenorhabditis elegans]
GI:392900992 GenBank ABZ32252.1 339 Sequence 6190 from patent US 7314974
GI:392900992 SwissProt G5EGN2.1 339 RecName: Full=Delta(9)-fatty-acid desaturase fat-6; AltName: Full=Fatty-acid desaturase 6; AltName: Full=Stearoyl-CoA desaturase fat-6 [Caenorhabditis elegans]

Related Sequences to LMP008247 proteins

Reference Database Accession Length Protein Name
GI:392900996 EMBL CAB08356.1 339 Protein FAT-6, isoform a [Caenorhabditis elegans]
GI:392900994 EMBL CAB08356.1 339 Protein FAT-6, isoform a [Caenorhabditis elegans]
GI:392900994 EMBL CAD20542.1 339 unnamed protein product [Caenorhabditis elegans]
GI:392900996 EMBL CAD20542.1 339 unnamed protein product [Caenorhabditis elegans]
GI:392900992 EMBL CAP26210.1 338 Protein CBR-FAT-6 [Caenorhabditis briggsae]
GI:392900996 GenBank AAF97550.1 339 stearoyl-CoA desaturase FAT-6 [Caenorhabditis elegans]
GI:392900994 GenBank AAF97550.1 339 stearoyl-CoA desaturase FAT-6 [Caenorhabditis elegans]
GI:392900996 GenBank ABZ32252.1 339 Sequence 6190 from patent US 7314974
GI:392900994 GenBank ABZ32252.1 339 Sequence 6190 from patent US 7314974
GI:392900992 GenBank EFP08568.1 338 CRE-FAT-6 protein [Caenorhabditis remanei]
GI:392900992 GenBank EGT37687.1 340 hypothetical protein CAEBREN_28282 [Caenorhabditis brenneri]
GI:392900992 GenBank EGT49299.1 340 hypothetical protein CAEBREN_08726 [Caenorhabditis brenneri]
GI:392900992 RefSeq XP_002633423.1 338 C. briggsae CBR-FAT-6 protein [Caenorhabditis briggsae]
GI:392900992 RefSeq XP_003100803.1 338 CRE-FAT-6 protein [Caenorhabditis remanei]
GI:392900996 RefSeq NP_001255595.1 339 Protein FAT-6, isoform a [Caenorhabditis elegans]
GI:392900994 RefSeq NP_001255595.1 339 Protein FAT-6, isoform a [Caenorhabditis elegans]
GI:392900996 SwissProt G5EGN2.1 339 RecName: Full=Delta(9)-fatty-acid desaturase fat-6; AltName: Full=Fatty-acid desaturase 6; AltName: Full=Stearoyl-CoA desaturase fat-6 [Caenorhabditis elegans]
GI:392900994 SwissProt G5EGN2.1 339 RecName: Full=Delta(9)-fatty-acid desaturase fat-6; AltName: Full=Fatty-acid desaturase 6; AltName: Full=Stearoyl-CoA desaturase fat-6 [Caenorhabditis elegans]