Gene/Proteome Database (LMPD)

LMPD ID
LMP008137
Gene ID
174227
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein TPH-1
Gene Symbol
tph-1
Synonyms
CELE_ZK1290.2
Chromosome
II

Proteins

Protein TPH-1, isoform a
Refseq ID NP_495584
Protein GI 115533973
UniProt ID G5EED8
mRNA ID NM_063183
Length 532
RefSeq Status REVIEWED
MDSLFQMASAMKFQYYSKKAAGKTMSNSVSMSSDNRMEDFKRRFRRSGSLGIPFVPEEDVKQLFTPTRTVRREASIREGDEEEGVQILTIIVKSSRVSEDISKMIANLPDHTRIKHLETRDSQDGSSKTMDVLLEIELFHYGKQEAMDLMRLNGLDVHEVSSTIRPTAIKEQYTEPGSDDATTGSEWFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMFAELALNYKHGEPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSENNIPQLEDICKFLKAKTGFRVRPVAGYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEPDTVHELMGHMALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLSSDDAADSPVKENGSNHERFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITTFQSAYFYTRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGALHYIL
Protein TPH-1, isoform b
Refseq ID NP_001022504
Protein GI 115532103
UniProt ID Q2V4U7
mRNA ID NM_001027333
Length 429
RefSeq Status REVIEWED
MIANLPDHTRIKHLETRDSQDGSSKTMDVLLEIELFHYGKQEAMDLMRLNGLDVHEVSSTIRPTAIKEQYTEPGSDDATTGSEWFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMFAELALNYKHGEPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSENNIPQLEDICKFLKAKTGFRVRPVAGYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEPDTVHELMGHMALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLSSDDAADSPVKENGSNHERFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITTFQSAYFYTRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGALHYIL

Gene Information

Entrez Gene ID
174227
Gene Name
Protein TPH-1
Gene Symbol
tph-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005622 IDA:WormBase C intracellular
GO:0005506 IEA:InterPro F iron ion binding
GO:0004510 ISS:WormBase F tryptophan 5-monooxygenase activity
GO:0040024 IMP:WormBase P dauer larval development
GO:0008340 IMP:WormBase P determination of adult lifespan
GO:0019915 IMP:WormBase P lipid storage
GO:0030511 IMP:WormBase P positive regulation of transforming growth factor beta receptor signaling pathway
GO:0046662 IMP:WormBase P regulation of oviposition
GO:0043051 IMP:WormBase P regulation of pharyngeal pumping
GO:0006587 IMP:WormBase P serotonin biosynthetic process from tryptophan

Domain Information

InterPro Annotations

Accession Description
IPR001273 ArAA_hydroxylase
IPR018301 ArAA_hydroxylase_Fe/CU_BS
IPR019774 Aromatic-AA_hydroxylase_C
IPR005963 Trp_5_mOase
IPR019773 Tyrosine_3-monooxygenase-like

UniProt Annotations

Entry Information

Gene Name
Protein TPH-1
Protein Entry
Q2V4U7_CAEEL
UniProt ID
Q2V4U7
Species
C. elegans

Identical and Related Proteins

Unique RefSeq proteins for LMP008137 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
115533973 RefSeq NP_495584 532 Protein TPH-1, isoform a
115532103 RefSeq NP_001022504 429 Protein TPH-1, isoform b

Identical Sequences to LMP008137 proteins

Reference Database Accession Length Protein Name
GI:115533973 EMBL CCD65929.1 532 Protein TPH-1, isoform a [Caenorhabditis elegans]
GI:115532103 EMBL CCD65930.1 429 Protein TPH-1, isoform b [Caenorhabditis elegans]
GI:115533973 GenBank AAD30115.1 532 tryptophan hydroxylase [Caenorhabditis elegans]
GI:115533973 GenBank AAY03769.1 532 Sequence 313 from patent US 6861256
GI:115533973 GenBank ABH73364.1 532 Sequence 313 from patent US 7041437

Related Sequences to LMP008137 proteins

Reference Database Accession Length Protein Name
GI:115533973 EMBL CAP31870.2 546 Protein CBR-TPH-1 [Caenorhabditis briggsae]
GI:115532103 EMBL CCD65929.1 532 Protein TPH-1, isoform a [Caenorhabditis elegans]
GI:115532103 GenBank AAD30115.1 532 tryptophan hydroxylase [Caenorhabditis elegans]
GI:115532103 GenBank AAY03769.1 532 Sequence 313 from patent US 6861256
GI:115532103 GenBank ABH73364.1 532 Sequence 313 from patent US 7041437
GI:115533973 GenBank ABZ31516.1 575 Sequence 5454 from patent US 7314974
GI:115532103 GenBank ABZ31516.1 575 Sequence 5454 from patent US 7314974
GI:115533973 GenBank EFP07801.1 532 CRE-TPH-1 protein [Caenorhabditis remanei]
GI:115533973 GenBank EGT55645.1 532 CBN-TPH-1 protein [Caenorhabditis brenneri]
GI:115532103 RefSeq NP_495584.4 532 Protein TPH-1, isoform a [Caenorhabditis elegans]
GI:115533973 RefSeq XP_002630549.1 526 C. briggsae CBR-TPH-1 protein [Caenorhabditis briggsae]
GI:115533973 RefSeq XP_003113889.1 532 CRE-TPH-1 protein [Caenorhabditis remanei]