Gene/Proteome Database (LMPD)

LMPD ID
LMP007999
Gene ID
178535
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein GBA-3
Gene Symbol
gba-3
Synonyms
CELE_F11E6.1
Alternate Names
Protein GBA-3
Chromosome
IV
EC Number
3.2.1.45

Proteins

Protein GBA-3, isoform a
Refseq ID NP_503119
Protein GI 17539758
UniProt ID G5ECR8
mRNA ID NM_070718
Length 522
RefSeq Status REVIEWED
MSRWKVVILCLLSFMFEIGHASFQCNPKTYDGAFLNIVCVCNATFCDEIEPIGEIAEGKAIVYRSSLDGDRLKRMSMKMKEKLRKNESVNVTITIDASERFQNIFGFGGAFTDSAGDQFVSLSETLQNYIVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDDVHDDFELKHFALPDEDLKLKIPFIKKAIEKTEGNIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFWGLTIQNEPSTGADMAWRWQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVLDDGRGLLPGWADTIFNDPEATKYADGVAVHWYGNLYSPAVLLDITQRHHPTKFIFGTEACAGYFGHHGPIMGDWFRAESYADDIITDLNHHVTGWTDWNLCLDETGGPNWAYNVVDSPIIVNRTAQEFYKQPMFYALGHFSKFLPRGSTRVFTKIEGNLAVSATSVVIEGGRRATVILSKASNSLLTRIVDSSTGFSIVLNLPPRSIHTVIWKKRK
Protein GBA-3, isoform b
Refseq ID NP_503118
Protein GI 17539756
UniProt ID G5ECR8
mRNA ID NM_070717
Length 522
RefSeq Status REVIEWED
MSRWKVVILCLLSFMFEIGHASFQCNPKTYDGAFLNIVCVCNATFCDEIEPIGEIAEGKAIVYRSSLDGDRLKRMSMKMKEKLRKNESVNVTITIDASERFQNIFGFGGAFTDSAGDQFVSLSETLQNYIVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDDVHDDFELKHFALPDEDLKLKIPFIKKAIEKTEGNIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFWGLTIQNEPSTGADMAWRWQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVLDDGRGLLPGWADTIFNDPEATKYADGVAVHWYGNLYSPAVLLDITQRHHPTKFIFGTEACAGYAIHHGPLMGDWFTAENYASDIISDLNHHFTGWTDWNLCLDDMGGPTWVDNFVDSPIIVNRTGQEFYKQPMFYAMGHFSKFLPRGSTRVFTKIEGNLAVSATSVVIEGGRRATVILSKASNSLLTRIVDSSTGFSIVLNLPPRSIHTVIWKKRK
Protein GBA-3, isoform c
Refseq ID NP_741501
Protein GI 25151335
UniProt ID G5ECR8
mRNA ID NM_171429
Length 458
RefSeq Status REVIEWED
MSRWKVVILCLLSFMFEIGHASFQCNPKTYDGAFLNIVCVCNATFCDEIEPIGEIAEGKAIVYRSSLDGDRLKRMSMKMKEKLRKNESVNVTITIDASERFQNIFGFGGAFTDSAGDQFVSLSETLQNYIVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDDVHDDFELKHFALPDEDLKLKIPFIKKAIEKTEGNIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFWGLTIQNEPSTGADMAWRWQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVLDDGRGLLPGWADTIFNDPEATKYADGVAVHWYGNLYSPAVLLDITQRHHPTKFIFGTEACAGYAIHHGPLMGDWFTAENYASDIISDLNHHFTGWTDWNLCLDDMGGPTWVDNFVDSPIIVNRTGQEFYKQPMFYAMGHFRHVLATLDIMVQ
Protein GBA-3, isoform d
Refseq ID NP_001255965
Protein GI 392902346
UniProt ID G5ECR8
mRNA ID NM_001269036
Length 525
RefSeq Status REVIEWED
MAFFSVRSSKIVFGLERSEEKGHASFQCNPKTYDGAFLNIVCVCNATFCDEIEPIGEIAEGKAIVYRSSLDGDRLKRMSMKMKEKLRKNESVNVTITIDASERFQNIFGFGGAFTDSAGDQFVSLSETLQNYIVDSYFGKNGLEYNIGRVPIASCDFSTHEYSYDDVHDDFELKHFALPDEDLKLKIPFIKKAIEKTEGNIQLFASPWSAPGWMKVTGRMRGGGAMRNDKRVYQAYADYFFKFFEAYSSHAITFWGLTIQNEPSTGADMAWRWQTMNYTAETMRDFLKKYLGPKLKENKLTETLKVMVLDDGRGLLPGWADTIFNDPEATKYADGVAVHWYGNLYSPAVLLDITQRHHPTKFIFGTEACAGYFGHHGPIMGDWFRAESYADDIITDLNHHVTGWTDWNLCLDETGGPNWAYNVVDSPIIVNRTAQEFYKQPMFYALGHFSKFLPRGSTRVFTKIEGNLAVSATSVVIEGGRRATVILSKASNSLLTRIVDSSTGFSIVLNLPPRSIHTVIWKKRK

Gene Information

Entrez Gene ID
178535
Gene Name
Protein GBA-3
Gene Symbol
gba-3
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0004348 IEA:UniProtKB-EC F glucosylceramidase activity
GO:0005975 IEA:InterPro P carbohydrate metabolic process
GO:0006665 IEA:UniProtKB-UniPathway P sphingolipid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
cel04142 Lysosome
ko04142 Lysosome
cel01100 Metabolic pathways
cel00600 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR017853 Glycoside hydrolase superfamily
IPR013781 Glycoside hydrolase, catalytic domain
IPR001139 Glycoside hydrolase, family 30

UniProt Annotations

Entry Information

Gene Name
Protein GBA-3
Protein Entry
GLCM3_CAEEL
UniProt ID
G5ECR8
Species
C. elegans

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=4; Name=a; IsoId=G5ECR8-1; Sequence=Displayed; Name=b; IsoId=G5ECR8-2; Sequence=VSP_045726, VSP_045727, VSP_045728, VSP_045729, VSP_045730, VSP_045731, VSP_045732, VSP_045733, VSP_045734, VSP_045735, VSP_045736; Name=c; IsoId=G5ECR8-3; Sequence=VSP_045726, VSP_045727, VSP_045728, VSP_045729, VSP_045730, VSP_045731, VSP_045732, VSP_045733, VSP_045734, VSP_045735, VSP_045736, VSP_045737, VSP_045738; Name=d; IsoId=G5ECR8-4; Sequence=VSP_045725;
Catalytic Activity D-glucosyl-N-acylsphingosine + H(2)O = D- glucose + N-acylsphingosine.
Pathway Lipid metabolism; sphingolipid metabolism.
Similarity Belongs to the glycosyl hydrolase 30 family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007999 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17539758 RefSeq NP_503119 522 Protein GBA-3, isoform a
17539756 RefSeq NP_503118 522 Protein GBA-3, isoform b
25151335 RefSeq NP_741501 458 Protein GBA-3, isoform c
392902346 RefSeq NP_001255965 525 Protein GBA-3, isoform d

Identical Sequences to LMP007999 proteins

Reference Database Accession Length Protein Name
GI:17539758 EMBL CAB02924.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:17539756 EMBL CAC35813.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:25151335 EMBL CAD42642.1 458 Protein GBA-3, isoform c [Caenorhabditis elegans]
GI:392902346 EMBL CCD31056.1 525 Protein GBA-3, isoform d [Caenorhabditis elegans]
GI:17539758 GenBank ABZ32302.1 522 Sequence 6240 from patent US 7314974
GI:17539758 GenBank ABZ32303.1 522 Sequence 6241 from patent US 7314974
GI:17539758 SwissProt G5ECR8.1 522 RecName: Full=Putative glucosylceramidase 3; Flags: Precursor [Caenorhabditis elegans]

Related Sequences to LMP007999 proteins

Reference Database Accession Length Protein Name
GI:17539756 EMBL CAB02924.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:392902346 EMBL CAB02924.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:25151335 EMBL CAB02924.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:25151335 EMBL CAC35813.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:392902346 EMBL CAC35813.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:17539758 EMBL CAC35813.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:17539758 EMBL CAD42642.1 458 Protein GBA-3, isoform c [Caenorhabditis elegans]
GI:17539758 EMBL CCD31056.1 525 Protein GBA-3, isoform d [Caenorhabditis elegans]
GI:392902346 GenBank ABZ32302.1 522 Sequence 6240 from patent US 7314974
GI:25151335 GenBank ABZ32302.1 522 Sequence 6240 from patent US 7314974
GI:17539756 GenBank ABZ32302.1 522 Sequence 6240 from patent US 7314974
GI:25151335 GenBank ABZ32303.1 522 Sequence 6241 from patent US 7314974
GI:17539756 GenBank ABZ32303.1 522 Sequence 6241 from patent US 7314974
GI:392902346 GenBank ABZ32303.1 522 Sequence 6241 from patent US 7314974
GI:17539758 RefSeq NP_503118.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:25151335 RefSeq NP_503118.1 522 Protein GBA-3, isoform b [Caenorhabditis elegans]
GI:25151335 RefSeq NP_503119.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:17539756 RefSeq NP_503119.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:392902346 RefSeq NP_503119.1 522 Protein GBA-3, isoform a [Caenorhabditis elegans]
GI:17539758 RefSeq XP_002632409.1 520 Hypothetical protein CBG00434 [Caenorhabditis briggsae]
GI:17539758 RefSeq NP_001255965.1 525 Protein GBA-3, isoform d [Caenorhabditis elegans]
GI:17539756 RefSeq NP_001255965.1 525 Protein GBA-3, isoform d [Caenorhabditis elegans]
GI:17539756 SwissProt G5ECR8.1 522 RecName: Full=Putative glucosylceramidase 3; Flags: Precursor [Caenorhabditis elegans]
GI:392902346 SwissProt G5ECR8.1 522 RecName: Full=Putative glucosylceramidase 3; Flags: Precursor [Caenorhabditis elegans]