Gene/Proteome Database (LMPD)

LMPD ID
LMP007986
Gene ID
177525
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein PLC-4
Gene Symbol
plc-4
Synonyms
CELE_R05G6.8
Chromosome
IV

Proteins

Protein PLC-4
Refseq ID NP_501213
Protein GI 17541792
UniProt ID Q21754
mRNA ID NM_068812
Length 751
RefSeq Status REVIEWED
MAKSVSPEEQAAAQAADEEKTKEELEWAEKGSLLCRIKNQKVKEMALVTIKSKQFLNYYSSYWFNFVPNALKSVALSELLEVRSGYQTDNLQRASKKYEFQELAPESRCFSVIFSHAKFLHKSVDFSADSKETRDKWVSVLTHLISVAKHQRVVFNETAWLIDKFQQADTNKNGLLSFDEVWNLLKRMNLQISERYAKAIFRESEFENSRDNKLNEKEFLNFFERLTDRPDLRFVMTQASSDNVETLTVADLQRFLTEEQGFENVDLKKAEQILTTFEQTVQDKQKEKLMGLMGMRRLMQSRWGNVFKPGHESIFQDMDQPLTHYFVNSSHNTYLTGLQVKGEATVEGYISALRKGARLLELDLFDGEHGEPVITHKRTFIESITLRNSLEAIKRTAFETSPYPVILTLENHVGFVQQAVMADLFKEILGDSLYIPPKDSHRHPLSSPNKLKRKFLLRGKKIILEEDIEEPDEDDSPTDKDKHHVHPHPVAPELSALIGLPSVKLSHNIYQDVNKHPFDGSPSLSENKVYTMFEAAVPIFTYTAERLVKSYPKGLRQDSSNMHPMVSWLCGIQSVAMNFQTAGEELDLNAGLFRINGNCGYVLKPSCLLDGVDPRSMAKPKLKLGIGLFSAQYLPKSEPGKEIIDPYVSVQIFGIPRDETKAKTRIIKDNGFNPEWRDNFYFTLSCPELAIIRFCVKDFDSTSSNDFVGEFSIPVMSLRTGFSQIQLNTGYQHTLDPSASLFVRIAMEEEY

Gene Information

Entrez Gene ID
177525
Gene Name
Protein PLC-4
Gene Symbol
plc-4
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
Protein PLC-4
Protein Entry
Q21754_CAEEL
UniProt ID
Q21754
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 2 EF-hand domains.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP007986 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17541792 RefSeq NP_501213 751 Protein PLC-4

Identical Sequences to LMP007986 proteins

Reference Database Accession Length Protein Name
GI:17541792 EMBL CBF62904.1 751 unnamed protein product [Caenorhabditis elegans]
GI:17541792 EMBL CBU87780.1 751 unnamed protein product [Caenorhabditis elegans]
GI:17541792 EMBL CBU96727.1 751 unnamed protein product [Caenorhabditis elegans]
GI:17541792 EMBL CCD71557.1 751 Protein PLC-4 [Caenorhabditis elegans]
GI:17541792 GenBank AGX54715.1 751 Sequence 9786 from patent US 8541208
GI:17541792 GenBank AGX64155.1 751 Sequence 28420 from patent US 8541208

Related Sequences to LMP007986 proteins

Reference Database Accession Length Protein Name
GI:17541792 EMBL CAP26450.1 752 Protein CBR-PLC-4 [Caenorhabditis briggsae]
GI:17541792 EMBL CDJ87672.1 751 Phospholipase C and C2 calcium-dependent membrane targeting domain containing protein [Haemonchus contortus]
GI:17541792 GenBank EFO93863.1 751 CRE-PLC-4 protein [Caenorhabditis remanei]
GI:17541792 GenBank EGT44001.1 786 hypothetical protein CAEBREN_30590, partial [Caenorhabditis brenneri]
GI:17541792 RefSeq XP_002633183.1 752 C. briggsae CBR-PLC-4 protein [Caenorhabditis briggsae]
GI:17541792 RefSeq XP_003107964.1 751 CRE-PLC-4 protein [Caenorhabditis remanei]