Gene/Proteome Database (LMPD)

LMPD ID
LMP007890
Gene ID
180904
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein MOM-1
Gene Symbol
mom-1
Synonyms
CELE_T07H6.2
Chromosome
X

Proteins

Protein MOM-1
Refseq ID NP_509054
Protein GI 17569079
UniProt ID Q22329
mRNA ID NM_076653
Length 442
RefSeq Status REVIEWED
MDNGHGYEEFELLEDGSLGECSTQVANATFLTISKLICLVVAFKFIKHIPISTTVRVYVHVFASTFTVMWFSRNHLQSAIIYNMFSLISLALAIKQFSGYIILAGNISLLIALQNFCRHYRSEDYFLSIRGILMIHIMRLTTVAFNLEKANSNKFRFVQFSSYVEYIYFPPFIIFGPYLSFEQFFKMRDKKWTGSENELGFIIQSLLAIFNAITLAIISSCHFEFFEPSSQFMEDALTAMSFRFSHYFVCLSTQAFVLMLGSDVVVANPLNIEFSRSTLQTVSEWNKPFHTFLHENIFKRRLFNSTACNVFFTFAVSSLLHGLDFQMTITLLALGFIAYSETVFRKRLSARYSMCVAAKACPVRSNSLSCKHRHSNKTGRALIINLFFLMLSMYHLVFTGMTFTDDYSAIGYPFDHAWKIWGSHYYSSFMISFLFLALSKII

Gene Information

Entrez Gene ID
180904
Gene Name
Protein MOM-1
Gene Symbol
mom-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030176 ISS:WormBase C integral component of endoplasmic reticulum membrane
GO:0008374 ISM:WormBase F O-acyltransferase activity
GO:0017147 ISS:WormBase F Wnt-protein binding
GO:0060069 IMP:WormBase P Wnt signaling pathway, regulating spindle positioning
GO:0045167 IMP:WormBase P asymmetric protein localization involved in cell fate determination
GO:0009792 IMP:WormBase P embryo development ending in birth or egg hatching
GO:0048598 IMP:WormBase P embryonic morphogenesis
GO:0001714 IMP:WormBase P endodermal cell fate specification
GO:0018345 ISS:WormBase P protein palmitoylation
GO:0061359 ISS:WormBase P regulation of Wnt signaling pathway by Wnt protein secretion
GO:0009786 IMP:WormBase P regulation of asymmetric cell division
GO:0007367 IEA:UniProtKB-KW P segment polarity determination

Domain Information

InterPro Annotations

Accession Description
IPR004299 Membrane bound O-acyl transferase, MBOAT

UniProt Annotations

Entry Information

Gene Name
Protein MOM-1
Protein Entry
Q22329_CAEEL
UniProt ID
Q22329
Species
C. elegans

Comments

Comment Type Description
Disruption Phenotype Defects in endoderm development, blastomere differentiation and mitotic spindle axis formation.
Function Implicated in the Wnt signaling pathway. Thought to be involved in lipid modification of Wnt proteins. Has a role in cell specification, specifically in blastomere signaling. Involved in cytosketetal polarity. Required for the orientation of mitotic spindle axis. {ECO:0000269|PubMed:10444600, ECO:0000269|PubMed:15020416, ECO:0000269|PubMed:9288750}.
Similarity Belongs to the membrane-bound acyltransferase family. Porcupine subfamily.
Subcellular Location Membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP007890 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17569079 RefSeq NP_509054 442 Protein MOM-1

Identical Sequences to LMP007890 proteins

Reference Database Accession Length Protein Name
GI:17569079 EMBL CCD74393.1 442 Protein MOM-1 [Caenorhabditis elegans]
GI:17569079 GenBank AAC47728.1 442 MOM-1 [Caenorhabditis elegans]
GI:17569079 SwissProt Q22329.2 442 RecName: Full=Probable protein-cysteine N-palmitoyltransferase porcupine; Short=Porc; AltName: Full=More of ms protein 1 [Caenorhabditis elegans]

Related Sequences to LMP007890 proteins

Reference Database Accession Length Protein Name
GI:17569079 EMBL CAP25618.1 444 Protein CBR-MOM-1 [Caenorhabditis briggsae]
GI:17569079 EMBL CDJ81291.1 1443 Membrane bound O-acyl transferase and Coiled-coil-containing protein 128 domain containing protein [Haemonchus contortus]
GI:17569079 GenBank EGT43151.1 444 CBN-MOM-1 protein [Caenorhabditis brenneri]
GI:17569079 GenBank EFO20748.2 454 MBOAT family protein [Loa loa]
GI:17569079 RefSeq XP_002644859.1 444 C. briggsae CBR-MOM-1 protein [Caenorhabditis briggsae]
GI:17569079 SwissProt A8WZ09.1 444 RecName: Full=Probable protein-cysteine N-palmitoyltransferase porcupine; AltName: Full=More of ms protein 1 [Caenorhabditis briggsae]