Gene/Proteome Database (LMPD)

LMPD ID
LMP007756
Gene ID
946574
Species
Escherichia coli K-12 (E. coli)
Gene Name
phosphomannomutase
Gene Symbol
cpsG
Synonyms
ECK2042; JW2033; manB; rfbK
Summary
None
Orthologs
View orthologs and multiple alignments for cpsG

Proteins

phosphomannomutase [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_416552
Protein GI 16129988
UniProt ID P24175
Length 456
RefSeq Status REVIEWED
MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKDKTLGELVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRTSNTEPVVRLNVESRGDVPLMEARTRTLLTLLNE

Gene Information

Entrez Gene ID
946574
Gene Name
phosphomannomutase
Gene Symbol
cpsG
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IBA:RefGenome C cytosol
GO:0000287 IEA:InterPro F magnesium ion binding
GO:0004615 IEA:UniProtKB-EC F phosphomannomutase activity
GO:0009298 IGI:EcoCyc P GDP-mannose biosynthetic process
GO:0009103 IEA:UniProtKB-KW P lipopolysaccharide biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
eco00520 Amino sugar and nucleotide sugar metabolism
ko00520 Amino sugar and nucleotide sugar metabolism
eco01110 Biosynthesis of secondary metabolites
eco00051 Fructose and mannose metabolism
ko00051 Fructose and mannose metabolism
eco01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5659 GDP-mannose biosynthesis
PWY-5659 GDP-mannose biosynthesis
PWY-5659 GDP-mannose biosynthesis
COLANSYN-PWY colanic acid building blocks biosynthesis
COLANSYN-PWY colanic acid building blocks biosynthesis
COLANSYN-PWY colanic acid building blocks biosynthesis
PWY-7323 superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR005843 A-D-PHexomutase_C
IPR016066 A-D-PHexomutase_CS
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005841 Alpha-D-phosphohexomutase_SF

UniProt Annotations

Entry Information

Gene Name
phosphomannomutase
Protein Entry
MANB_ECOLI
UniProt ID
P24175
Species
E. coli

Comments

Comment Type Description
Catalytic Activity Alpha-D-mannose 1-phosphate = D-mannose 6- phosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000250};
Function Involved in the biosynthesis of the capsular polysaccharide colanic acid.
Pathway Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6- phosphate: step 2/2.
Similarity Belongs to the phosphohexose mutase family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007756 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16129988 RefSeq NP_416552 456 phosphomannomutase [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007756 proteins

Reference Database Accession Length Protein Name
GI:16129988 EMBL CDY59355.1 456 phosphomannomutase [Escherichia coli]
GI:16129988 EMBL CDZ20869.1 456 phosphomannomutase [Escherichia coli]
GI:16129988 GenBank KGA85592.1 456 phosphomannomutase [Escherichia coli]
GI:16129988 GenBank KGL68984.1 456 phosphomannomutase CpsG [Escherichia coli NCTC 50110]
GI:16129988 gnl PRJNA257976 456 phosphomannomutase [Escherichia coli BW25113]
GI:16129988 gnl IGS 456 phosphomannomutase [Escherichia coli ER2796]

Related Sequences to LMP007756 proteins

Reference Database Accession Length Protein Name
GI:16129988 GenBank EOV52038.1 456 phosphomannomutase [Escherichia coli KTE61]
GI:16129988 GenBank ESD00867.1 456 phosphomannomutase [Escherichia coli 113302]
GI:16129988 GenBank KDX98821.1 456 phosphoglucomutase/phosphomannomutase, C-terminal domain protein [Escherichia coli 2-316-03_S3_C1]
GI:16129988 gnl zhongguo 456 Phosphomannomutase [Escherichia coli P12b]
GI:16129988 RefSeq YP_006169169.1 456 phosphomannomutase [Escherichia coli P12b]
GI:16129988 RefSeq WP_014640987.1 456 phosphomannomutase [Escherichia coli]