Gene/Proteome Database (LMPD)

LMPD ID
LMP007669
Gene ID
948068
Species
Escherichia coli K-12 (E. coli)
Gene Name
KDO phosphoethanolamine transferase, Ca(2+)-inducible
Gene Symbol
eptB
Synonyms
ECK3533; JW5660; pagC; yhjW
Summary
Localized to the inner membrane by subcellular fractionation (Reynolds, 2005). [More information is available at EcoGene: EG12267]. The eptB gene encodes the Ca2+-induced phosphoethanolamine transferase . [More information is available at EcoCyc: EG12267].
Orthologs
View orthologs and multiple alignments for eptB

Proteins

KDO phosphoethanolamine transferase, Ca(2+)-inducible [Escherichia coli str. K-12 substr. MG1655]
Refseq ID NP_418002
Protein GI 90111611
UniProt ID P37661
Length 563
RefSeq Status REVIEWED
MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWKGISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRSLAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAWARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDLYAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLIILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVIDQVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQAFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN

Gene Information

Entrez Gene ID
948068
Gene Name
KDO phosphoethanolamine transferase, Ca(2+)-inducible
Gene Symbol
eptB
Species
Escherichia coli K-12

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:EcoCyc C plasma membrane
GO:0043838 IDA:EcoCyc F phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity
GO:0008484 IEA:InterPro F sulfuric ester hydrolase activity
GO:0009245 IDA:EcoCyc P lipid A biosynthetic process
GO:0009103 IEA:UniProtKB-KW P lipopolysaccharide biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR017849 Alkaline phosphatase-like, alpha/beta/alpha
IPR017850 Alkaline-phosphatase-like, core domain
IPR012549 DUF1705
IPR000917 Sulfatase

UniProt Annotations

Entry Information

Gene Name
KDO phosphoethanolamine transferase, Ca(2+)-inducible
Protein Entry
EPTB_ECOLI
UniProt ID
P37661
Species
E. coli

Comments

Comment Type Description
Cofactor Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:15795227};
Enzyme Regulation Inhibited by calcium concentrations higher than 1 mM. {ECO:0000269|PubMed:15795227}.
Function Catalyzes the addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-D-manno-octulosonic acid (KDO) residue of a KDO(2)-lipid A. Phosphatidylethanolamines with one unsaturated acyl group functions as pEtN donors and the reaction releases diacylglycerol. {ECO:0000269|PubMed:15795227}.
Similarity Belongs to the phosphoethanolamine transferase family. EptB subfamily. {ECO:0000305}.
Subcellular Location Cell inner membrane {ECO:0000269|PubMed:15795227}; Multi-pass membrane protein {ECO:0000269|PubMed:15795227}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007669 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
90111611 RefSeq NP_418002 563 KDO phosphoethanolamine transferase, Ca(2+)-inducible [Escherichia coli str. K-12 substr. MG1655]

Identical Sequences to LMP007669 proteins

Reference Database Accession Length Protein Name
GI:90111611 GenBank KHI11280.1 563 phosphoethanolamine transferase [Escherichia coli]
GI:90111611 GenBank KHI15686.1 563 phosphoethanolamine transferase [Escherichia coli]
GI:90111611 GenBank KHI57899.1 563 phosphoethanolamine transferase [Escherichia coli]
GI:90111611 GenBank KHI78097.1 563 phosphoethanolamine transferase [Escherichia coli]
GI:90111611 GenBank KHI88526.1 563 phosphoethanolamine transferase [Escherichia coli]
GI:90111611 gnl IGS 563 KDO phosphoethanolamine transferase, Ca(2+)-inducible [Escherichia coli ER2796]

Related Sequences to LMP007669 proteins

Reference Database Accession Length Protein Name
GI:90111611 GenBank ABB02171.1 574 EptB [Escherichia coli str. K-12 substr. W3110]
GI:90111611 GenBank EFO57509.1 563 arylsulfatase [Escherichia coli MS 145-7]
GI:90111611 GenBank EGI08777.1 574 membrane-protein YhjW [Escherichia coli H736]
GI:90111611 GenBank EGJ07811.1 574 arylsulfatase [Escherichia coli D9]
GI:90111611 gnl mgcchina 574 conserved hypothetical protein [Shigella boydii Sb227]
GI:90111611 gnl PRJNA260958 563 phosphoethanolamine transferase [Escherichia coli FAP1]