LIPID MAPS

LMPD ID

LMP007527

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Spo1p

Gene Symbol

SPO1

Synonyms

-

Chromosome

XIV

EC Number

3.1.1.-

Spo1p
Refseq ID	NP_014386
Protein GI	9755342
UniProt ID	P53541
mRNA ID	NM_001182851
Length	631
MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDNDLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNGLLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDNYPNGSKLKRIFEKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFKITYNQSEVSSMLPTGRGVFSNDYDLYYKNCLGCILTKRTMDRLPRKKKFSPFCLQCFKDYCYS

Entrez Gene ID

Gene Name

Spo1p

Gene Symbol

SPO1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005783	IDA:SGD	C	endoplasmic reticulum
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005634	IDA:SGD	C	nucleus
GO:0005628	IDA:SGD	C	prospore membrane
GO:0004620	ISS:SGD	F	phospholipase activity
GO:0007126	IEA:UniProtKB-KW	P	meiotic nuclear division
GO:0009395	IEA:InterPro	P	phospholipid catabolic process
GO:0030474	IMP:SGD	P	spindle pole body duplication
GO:0070583	IMP:SGD	P	spore membrane bending pathway

Accession	Description
IPR016035	Acyl transferase/acyl hydrolase/lysophospholipase
IPR002642	Lysophospholipase, catalytic domain

Gene Name

Spo1p

Protein Entry

SPO1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Regulates spindle pole duplication in meiosis I, but not in mitosis. Required for meiosis I, meiosis II chromosome segregation and spore formation. Binds phosphatidylinositol (4)P mono- and polyphosphates. {ECO:0000269\|PubMed:10855497, ECO:0000269\|PubMed:17179081}.
Induction	Induced early in sporulation. Not detected during vegetative growth
Induction	Induced early in sporulation. Not detected during vegetative growth. {ECO:0000269\|PubMed:10855497}.
Ptm	Glycosylated
Ptm	Glycosylated. {ECO:0000269\|PubMed:17179081}.
Sequence Caution	Sequence=AAB38425.1; Type=Erroneous gene model prediction; Evidence= ; Sequence=CAA95872.1; Type=Erroneous gene model prediction; Evidence= ;
Sequence Caution	Sequence=AAB38425.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAA95872.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity	Belongs to the lysophospholipase family
Similarity	Belongs to the lysophospholipase family. {ECO:0000305}.
Similarity	Contains 1 PLA2c domain. {ECO:0000255\|PROSITE- ProRule:PRU00555}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Subunit	Interacts with SPO23
Subunit	Interacts with SPO23. {ECO:0000269\|PubMed:17179081}.