Gene/Proteome Database (LMPD)

LMPD ID
LMP007514
Gene ID
851285
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
carnitine O-acetyltransferase YAT1
Gene Symbol
YAT1
Synonyms
-
Alternate Names
carnitine O-acetyltransferase YAT1
Chromosome
I
EC Number
2.3.1.7

Proteins

carnitine O-acetyltransferase YAT1
Refseq ID NP_009420
Protein GI 6319337
UniProt ID P80235
mRNA ID NM_001178226
Length 687
RefSeq Status PROVISIONAL
MPNLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAENLDALNTLHERLLEYDARLAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIPPGPGEPSCHLQTDATSHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWSNIRDYLFHADDCTNWRNLKLIDSALFVVCLDDVAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNVQTGTCLNRWYDKLQLIVTKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVTKNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVNLDFSNYGASHIKTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFVKSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELPPIFRDKSWTTMQNNVLSTSNCGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSRHRQTARFASLMEKSLLEIDRIFKRQQARAAKPAARTTASANTKSEDMKYLLSGYDYFDVSVSG

Gene Information

Entrez Gene ID
851285
Gene Name
carnitine O-acetyltransferase YAT1
Gene Symbol
YAT1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0005739 IDA:SGD C mitochondrion
GO:0004092 ISS:SGD F carnitine O-acetyltransferase activity
GO:0006066 IGI:SGD P alcohol metabolic process
GO:0009437 IMP:SGD P carnitine metabolic process
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process
GO:0006810 IEA:UniProtKB-KW P transport

KEGG Pathway Links

KEGG Pathway ID Description
sce04146 Peroxisome

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY3O-4 carnitine shuttle

REACTOME Pathway Links

REACTOME Pathway ID Description
5618120 Import of palmitoyl-CoA into the mitochondrial matrix
5618608 PPARA activates gene expression

Domain Information

InterPro Annotations

Accession Description
IPR000542 Acyltransferase ChoActase/COT/CPT

UniProt Annotations

Entry Information

Gene Name
carnitine O-acetyltransferase YAT1
Protein Entry
CACM_YEAST
UniProt ID
P80235
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Acetyl-CoA + carnitine = CoA + O- acetylcarnitine.
Function Involved in the transfer of acetyl-CoA into mitochondria. May also be involved in the metabolism of acetate and of ethanol.
Induction By ethanol and by acetate. Repressed by glucose, and to a lesser extent, by galactose. Derepressed by glycerol.
Interaction Q01574:ACS1; NbExp=1; IntAct=EBI-3928, EBI-2128;
Similarity Belongs to the carnitine/choline acetyltransferase family. {ECO:0000305}.
Subcellular Location Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.

Identical and Related Proteins

Unique RefSeq proteins for LMP007514 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6319337 RefSeq NP_009420 687 carnitine O-acetyltransferase YAT1

Identical Sequences to LMP007514 proteins

Reference Database Accession Length Protein Name
GI:6319337 EMBL CAY04419.1 687 unnamed protein product [Saccharomyces cerevisiae]
GI:6319337 EMBL CBN63529.1 687 unnamed protein product [Saccharomyces cerevisiae]
GI:6319337 EMBL CBN60637.1 687 unnamed protein product [Saccharomyces cerevisiae]
GI:6319337 EMBL CBN65246.1 687 unnamed protein product [Saccharomyces cerevisiae]
GI:6319337 GenBank ABZ27459.1 687 Sequence 1397 from patent US 7314974
GI:6319337 Third Party Genbank DAA07004.1 687 TPA: carnitine O-acetyltransferase YAT1 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007514 proteins

Reference Database Accession Length Protein Name
GI:6319337 EMBL CAY77668.1 687 Yat1p [Saccharomyces cerevisiae EC1118]
GI:6319337 GenBank EHN08666.1 687 Yat1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6319337 GenBank EWG87935.1 687 Yat1p [Saccharomyces cerevisiae R008]
GI:6319337 GenBank EWG92700.1 687 Yat1p [Saccharomyces cerevisiae P301]
GI:6319337 GenBank EWG97745.1 687 Yat1p [Saccharomyces cerevisiae R103]
GI:6319337 GenBank EWH19739.1 687 Yat1p [Saccharomyces cerevisiae P283]