LIPID MAPS

LMPD ID

LMP007469

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

calmodulin

Gene Symbol

CMD1

Synonyms

-

Alternate Names

calmodulin

Chromosome

II

calmodulin
Refseq ID	NP_009667
Protein GI	6319585
UniProt ID	P06787
mRNA ID	NM_001178457
Length	147
RefSeq Status	PROVISIONAL
MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALLSK

Entrez Gene ID

Gene Name

calmodulin

Gene Symbol

CMD1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005935	IDA:SGD	C	cellular bud neck
GO:0005934	IDA:SGD	C	cellular bud tip
GO:0005823	IDA:SGD	C	central plaque of spindle pole body
GO:0000131	IDA:SGD	C	incipient cellular bud site
GO:0043332	IDA:SGD	C	mating projection tip
GO:0005509	IDA:SGD	F	calcium ion binding
GO:0048306	IDA:SGD	F	calcium-dependent protein binding
GO:0006607	IMP:SGD	P	NLS-bearing protein import into nucleus
GO:0007114	IMP:SGD	P	cell budding
GO:0007010	IMP:SGD	P	cytoskeleton organization
GO:0000742	IMP:SGD	P	karyogamy involved in conjugation with cellular fusion
GO:0016237	IMP:SGD	P	microautophagy
GO:0006661	IMP:SGD	P	phosphatidylinositol biosynthetic process
GO:0006898	IMP:SGD	P	receptor-mediated endocytosis
GO:0051300	IMP:SGD	P	spindle pole body organization
GO:0042991	IMP:SGD	P	transcription factor import into nucleus
GO:0042144	IDA:SGD	P	vacuole fusion, non-autophagic

KEGG Pathway ID	Description
ko04070	Phosphatidylinositol signaling system
sce04070	Phosphatidylinositol signaling system

Gene Name

calmodulin

Protein Entry

CALM_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. {ECO:0000269\|PubMed:10339566}.
Interaction	P23287:CNA1; NbExp=3; IntAct=EBI-3976, EBI-12771; Q04439:MYO5; NbExp=7; IntAct=EBI-3976, EBI-11687; P32380:SPC110; NbExp=2; IntAct=EBI-3976, EBI-12369;
Miscellaneous	This protein has three functional calcium-binding sites.
Ptm	The N-terminus is blocked.
Similarity	Belongs to the calmodulin family. {ECO:0000305}.
Similarity	Contains 4 EF-hand domains. {ECO:0000255\|PROSITE- ProRule:PRU00448}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269\|PubMed:8247006}.
Subunit	Component of the SPC110 complex containing at least CMD1, SPC29, SPC42 and SCP110. Interacts with SPC110. {ECO:0000269\|PubMed:10339566, ECO:0000269\|PubMed:8247006}.

Protein GI	Database	Accession	Length	Protein Name
6319585	RefSeq	NP_009667	147	calmodulin

Reference	Database	Accession	Length	Protein Name
GI:6319585	GenBank	AGA48847.1	147	Sequence 42 from patent US 8324455
GI:6319585	GenBank	EWG87689.1	147	Cmd1p [Saccharomyces cerevisiae R008]
GI:6319585	GenBank	EWG92464.1	147	Cmd1p [Saccharomyces cerevisiae P301]
GI:6319585	GenBank	EWG97546.1	147	Cmd1p [Saccharomyces cerevisiae R103]
GI:6319585	GenBank	EWH19507.1	147	Cmd1p [Saccharomyces cerevisiae P283]
GI:6319585	gnl	McCuskerlabDuke	147	Cmd1p [Saccharomyces cerevisiae YJM993]

Reference	Database	Accession	Length	Protein Name
GI:6319585	DBBJ	GAA21657.1	147	K7_Cmd1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6319585	EMBL	CAG58389.1	147	unnamed protein product [Candida glabrata]
GI:6319585	GenBank	EJT41753.1	147	CMD1-like protein [Saccharomyces kudriavzevii IFO 1802]
GI:6319585	PDB	1LKJ	146	Chain A, Nmr Structure Of Apo Calmodulin From Yeast Saccharomyces Cerevisiae
GI:6319585	PDB	2LHI	176	Chain A, Solution Structure Of Ca2+CNA1 PEPTIDE-Bound Ycam
GI:6319585	RefSeq	XP_445478.1	147	hypothetical protein [Candida glabrata CBS 138]