LIPID MAPS

LMPD ID

LMP007456

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

lipid-binding protein HSP12

Gene Symbol

HSP12

Synonyms

GLP1; HOR5

Alternate Names

lipid-binding protein HSP12

Chromosome

VI

lipid-binding protein HSP12
Refseq ID	NP_116640
Protein GI	14318506
UniProt ID	P22943
mRNA ID	NM_001179952
Length	109
RefSeq Status	PROVISIONAL
MSDAGRKGFGEKASEALKPDSQKSYAEQGKEYITDKADKVAGKVQPEDNKGVFQGVHDSAEKGKDNAEGQGESLADQARDYMGAAKSKLNDAVEYVSGRVHGEEDPTKK

Entrez Gene ID

Gene Name

lipid-binding protein HSP12

Gene Symbol

HSP12

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005829	IDA:SGD	C	cytosol
GO:0005768	IDA:SGD	C	endosome
GO:0005886	IDA:SGD	C	plasma membrane
GO:0008289	IDA:SGD	F	lipid binding
GO:0007155	IDA:SGD	P	cell adhesion
GO:0034605	IMP:SGD	P	cellular response to heat
GO:0071470	IMP:SGD	P	cellular response to osmotic stress
GO:0034599	IMP:SGD	P	cellular response to oxidative stress
GO:0007009	IMP:SGD	P	plasma membrane organization

Accession	Description
IPR007250	Heat shock protein 9/12
IPR016360	Heat shock protein, 9/12, fungi

Gene Name

lipid-binding protein HSP12

Protein Entry

HSP12_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	May play a role in a switch from carbohydrate utilizing metabolism to fatty acid utilizing metabolism.
Induction	Strong, by heat shock, by entry in the stationary growth phase, and by cAMP, probably via the activity of a cAMP- dependent protein kinase. By glucose starvation and by fatty acids.
Miscellaneous	Present with 4490 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	To S.pombe hsp9 and C.albicans WH11. {ECO:0000305}.

Protein GI	Database	Accession	Length	Protein Name
14318506	RefSeq	NP_116640	109	lipid-binding protein HSP12

Reference	Database	Accession	Length	Protein Name
GI:14318506	DBBJ	GAA23069.1	109	K7_Hsp12p [Saccharomyces cerevisiae Kyokai no. 7]
GI:14318506	GenBank	ABZ47934.1	109	Sequence 21872 from patent US 7314974
GI:14318506	GenBank	EIW10750.1	109	Hsp12p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:14318506	PDB	2L9Q	109	Chain A, Structural Characterization Of Small Heat Shock Protein (Hsp12)
GI:14318506	PDB	2LJL	109	Chain A, Nmr Structure Of Hsp12 In The Presence Of Dpc
GI:14318506	Third Party Genbank	DAA12425.1	109	TPA: lipid-binding protein HSP12 [Saccharomyces cerevisiae S288c]

Reference	Database	Accession	Length	Protein Name
GI:14318506	GenBank	AAL06077.1	109	12 kDa heat shock protein [Saccharomyces cerevisiae]
GI:14318506	GenBank	EDN59135.1	109	heat shock protein 12 [Saccharomyces cerevisiae YJM789]
GI:14318506	GenBank	EEU04229.1	109	Hsp12p [Saccharomyces cerevisiae JAY291]
GI:14318506	GenBank	EHN07337.1	109	Hsp12p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:14318506	GenBank	EWG96252.1	109	Hsp12p [Saccharomyces cerevisiae R103]
GI:14318506	PDB	4AXP	109	Chain A, Nmr Structure Of Hsp12, A Protein Induced By And Required For Dietary Restriction-Induced Lifespan Extension In Yeast.