LIPID MAPS

LMPD ID

LMP007427

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

phosphatidylinositol-3-phosphatase YMR1

Gene Symbol

YMR1

Synonyms

-

Chromosome

X

EC Number

3.1.3.64

phosphatidylinositol-3-phosphatase YMR1
Refseq ID	NP_012644
Protein GI	6322570
UniProt ID	P47147
mRNA ID	NM_001181768
Length	688
MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK

Entrez Gene ID

Gene Name

phosphatidylinositol-3-phosphatase YMR1

Gene Symbol

YMR1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005737	IEA:UniProtKB-KW	C	cytoplasm
GO:0003729	IDA:SGD	F	mRNA binding
GO:0004438	IMP:UniProtKB	F	phosphatidylinositol-3-phosphatase activity
GO:0004725	IEA:InterPro	F	protein tyrosine phosphatase activity
GO:0046856	IMP:UniProtKB	P	phosphatidylinositol dephosphorylation

REACTOME Pathway ID	Description
5618023	Metabolism
5618091	Metabolism of lipids and lipoproteins
5618611	PI Metabolism
5618126	Phospholipid metabolism
5618612	Synthesis of PIPs at the late endosome membrane
5618610	Synthesis of PIPs at the plasma membrane

Accession	Description
IPR010569	Myotubularin-like phosphatase domain
IPR016130	Protein-tyrosine phosphatase, active site
IPR029021	Protein-tyrosine phosphatase-like

Gene Name

phosphatidylinositol-3-phosphatase YMR1

Protein Entry

YMR1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	1-phosphatidyl-1D-myo-inositol 3-phosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol + phosphate.
Function	Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity. {ECO:0000269\|PubMed:10900271, ECO:0000269\|PubMed:15169871}.
Miscellaneous	Present with 1080 molecules/cell in log phase SD medium
Miscellaneous	Present with 1080 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Similarity	Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily
Similarity	Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. {ECO:0000305}.
Similarity	Contains 1 myotubularin phosphatase domain
Similarity	Contains 1 myotubularin phosphatase domain. {ECO:0000255\|PROSITE-ProRule:PRU00669}.
Subcellular Location	Cytoplasm .
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:14562095}.