Gene/Proteome Database (LMPD)

LMPD ID
LMP007410
Gene ID
856595
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gpi16p
Gene Symbol
GPI16
Synonyms
-
Alternate Names
Gpi16p
Chromosome
VIII

Proteins

Gpi16p
Refseq ID NP_012058
Protein GI 6321982
UniProt ID P38875
mRNA ID NM_001179319
Length 610
RefSeq Status PROVISIONAL
MILTLAYFMLGTLLLGVFAEDTVSQIGINDSLWYPYDEALVLKPLPNNDLLLSFAFQLQSEPFDPAVSSMSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKEAGASGVELWSQVQAMDQEQAFHNWKKLSNSLSGLFCSSLNFIDESRTTFPRRSYASDIGAPLFNSTEKLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISLDIATICSEDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLRCDTDKPFDSYQCFPLPEPSQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLSVDDTIFSTHDNCFDLSNDQNEGGSGYDFILESTDTTKVTPIVPVPIHVSRSLTGNGQDRGGMRIVFHNDNDTPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQENDIILDKYYLQAADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVITVLSLESSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFGMLYNLMVKRMVTVEEADKITLQSGLKYKLLKLKEKFLGKKKTKTD

Gene Information

Entrez Gene ID
856595
Gene Name
Gpi16p
Gene Symbol
GPI16
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042765 IDA:SGD C GPI-anchor transamidase complex
GO:0003923 IMP:SGD F GPI-anchor transamidase activity
GO:0016255 IMP:SGD P attachment of GPI anchor to protein

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR007245 GPI transamidase component PIG-T

UniProt Annotations

Entry Information

Gene Name
Gpi16p
Protein Entry
GPI16_YEAST
UniProt ID
P38875
Species
Yeast (S288c)

Comments

Comment Type Description
Caution It is uncertain whether Met-1 or Met-9 is the initiator. {ECO:0000305}.
Function Component of the GPI transamidase complex. Involved in transfer of GPI to proteins. {ECO:0000269|PubMed:11483512, ECO:0000269|PubMed:11598210}.
Interaction P39012:GAA1; NbExp=3; IntAct=EBI-24869, EBI-7252; P49018:GPI8; NbExp=3; IntAct=EBI-24869, EBI-7822;
Miscellaneous Present with 1680 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Ptm The disulfide bond between GPI8 and GPI16 is important for normal enzyme activity. {ECO:0000250}.
Sequence Caution Sequence=AAB68365.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the PIGT family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:11598210}; Single-pass type I membrane protein {ECO:0000269|PubMed:11598210}.
Subunit Forms a complex with CDC91, GPI17, GPI8 and GAA1. {ECO:0000269|PubMed:11598210}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007410 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321982 RefSeq NP_012058 610 Gpi16p

Identical Sequences to LMP007410 proteins

Reference Database Accession Length Protein Name
GI:6321982 GenBank AEH67656.1 610 Sequence 39 from patent US 7928215
GI:6321982 GenBank AFQ84265.1 610 Sequence 39 from patent US 8252294
GI:6321982 SwissProt P38875.2 610 RecName: Full=GPI transamidase component GPI16; Flags: Precursor [Saccharomyces cerevisiae S288c]
GI:6321982 Third Party Genbank DAA06880.1 610 TPA: Gpi16p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007410 proteins

Reference Database Accession Length Protein Name
GI:6321982 GenBank EDV09230.1 610 GPI transamidase component GPI16 precursor [Saccharomyces cerevisiae RM11-1a]
GI:6321982 GenBank EWG85833.1 610 Gpi16p [Saccharomyces cerevisiae R008]
GI:6321982 GenBank EWG90757.1 610 Gpi16p [Saccharomyces cerevisiae P301]
GI:6321982 GenBank EWG95533.1 610 Gpi16p [Saccharomyces cerevisiae R103]
GI:6321982 GenBank EWH18207.1 610 Gpi16p [Saccharomyces cerevisiae P283]
GI:6321982 gnl McCuskerlabDuke 610 Gpi16p [Saccharomyces cerevisiae YJM993]